The emergence of relationality in governance of climate change adaptation

This chapter presents the emergence of relationality as an individual and collective capacity that has the potential to enable transformative adaptation to meet future climate challenges. Given that people create the social systems that influence their lives, the capacity for adaptation to climate change may be viewed as both an individual attribute constructed through social learning and knowledge exchange and a fundamental component of an enabling environment of social institutions. Governance of climate adaptation, therefore, requires a deeper consideration of the moral and ethical motivation and behavior of participants. The concept of relationality may be operationalized in governance as capacity building through transformative dialogue processes within and among stakeholders designed to generate relational responsibility. Five governance approaches are briefly examined for their potential to facilitate the emergence of relationality including (i) polycentric (ii) middle-out, (iii) collaborative, (iv) transformational, and (v) experimental governance. Key attributes of these processes are synthesized into a relational governance model. Together, these concepts are used to examine two case studies from New South Wales (NSW) Australia that illustrate that relationality can be enabled and expressed in existing forms of governance. This is the case when government is prepared to experiment and improvise adaptation practices across scales and contexts and embrace the norms, values, relations, ways of thinking, paradigms, and mental models that a diversity of actors can collectively bring to bear on a complex problem. These kinds of approaches need to become normalized across formal and informal adaptation governance

Translational control of retroviruses.

All replication-competent retroviruses contain three main reading frames, gag, pol and env, which are used for the synthesis of structural proteins, enzymes and envelope proteins respectively. Complex retroviruses, such as lentiviruses, also code for regulatory and accessory proteins that have essential roles in viral replication. The concerted expression of these genes ensures the efficient polypeptide production required for the assembly and release of new infectious progeny virions. Retroviral protein synthesis takes place in the cytoplasm and depends exclusively on the translational machinery of the host infected cell. Therefore, not surprisingly, retroviruses have developed RNA structures and strategies to promote robust and efficient expression of viral proteins in a competitive cellular environment