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13 research outputs found
Deep Sequencing of Random Mutant Libraries Reveals the Active Site of the Narrow Specificity CphA Metallo-β-Lactamase is Fragile to Mutations
Author
A Felici
B Segatore
+34Â more
B Sullivan
BG Miller
BV Adkar
C Bebrone
C Bebrone
C Bebrone
C Bebrone
D Xu
DM Fowler
DM Fowler
F Simona
G Garau
IC Materon
J Petrosino
J Yuan
JF Fisher
L Jiang
L Zheng
LB Horton
M Hernandez Valladares
M Vanhove
MA Stiffler
NG Brown
O Massidda
S Haruta
S Wu
SC Mehta
T Hinkley
T Palzkill
TD Schneider
W Huang
Y Yang
Z Deng
Z Zhang
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
The spatial architecture of protein function and adaptation
Author
AI Shulman
Arjun Raman
+38Â more
B Kuhlman
BV Adkar
CA Voigt
CB Anfinsen
CN Chi
D Jain
DM Fowler
E Kussell
FC Peterson
FD Bushman
Frank J. Poelwijk
FW Studier
FW Whipple
G Tiana
GM Süel
JA Draghi
JB Kinney
JD Bloom
KA Reynolds
M Niethammer
M Socolich
MB Elowitz
ME Hatley
N Halabi
P Bradley
R Lutz
Rama Ranganathan
Richard N. McLaughlin Jr
RRO Smock
S Bershtein
SL Dove
SW Lockless
T Clackson
T van Opijnen
VJ Hilser
Walraj S. Gosal
WP Russ
Z Songyang
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
Measuring the activity of protein variants on a large scale using deep mutational scanning
Author
A Ernst
AM Levin
+39Â more
B Ge
BC Cunningham
BV Adkar
CE Tinberg
CL Araya
CL Araya
D Melamed
DG Gibson
DM Fowler
DM Fowler
DM Fowler
Douglas M Fowler
E Firnberg
E Procko
F Meacham
G Pál
I Kim
Jason J Stephany
JB Hiatt
KA Reynolds
L Brocchieri
LM Starita
M Dai
MG Gold
MP Cox
MW Traxlmayr
NC Wu
NJ Loman
PC Jain
R Knight
RD Gietz
RN McLaughlin
RT Hietpas
SA Gai
SS Sidhu
Stanley Fields
TA Whitehead
TR Wagenaar
Y Fujino
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
Learning Quantitative Sequence–Function Relationships from Massively Parallel Experiments
Author
A Jolma
A Jolma
+46Â more
A Melnikov
A Oliphant
A Zykovich
AD Ellington
BV Adkar
C Tuerk
D Wong
DM Fowler
DM Fowler
E Holmqvist
E Sharon
Gurinder S. Atwal
I Liachko
JB Kinney
JB Kinney
JB Kinney
JB Kinney
JB Kinney
JC Kwasnieski
Justin B. Kinney
K Rajan
KM Schlinkmann
L Herzenberg
L Paninski
M Berger
M Kouh
M Slattery
N Peterman
P Oikonomou
RP Patwardhan
RP Patwardhan
RT Hietpas
S Khan
S Maerkl
S Mukherjee
SB Thyme
T Cover
T Sharpee
T Sharpee
TA Whitehead
TK Blackwell
W Bialek
W Wright
WL Noderer
X Meng
Y Zhao
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
TRPV1 temperature activation is specifically sensitive to strong decreases in amino acid hydrophobicity
Author
A Dhaka
BV Adkar
+51Â more
CE Paulsen
CJ Bohlen
D McKemy
DA Doyle
DE Clapham
DM Fowler
E Cao
E Cao
E Holmqvist
EF Pettersen
EO Gracheva
F Sievers
F Yang
F Yang
H Hu
H Li
J Chen
J Grandl
J Grandl
J Kyte
J Siemens
J Yao
J Yao
JB Davis
JF Cordero-Morales
K Kang
KW Huynh
L Moparthi
L Zhong
L Zubcevic
M Bandell
M Goujon
M Liao
M Martin
MJ Caterina
MJ Caterina
R Latorre
S Chowdhury
S Jabba
S Jordt
S Ryu
S Seoh
S-E Jordt
SH White
SK Aggarwal
T Haltia
T Voets
T Voets
Y Gao
Z Wei
Z Winter
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
Growth tradeoffs produce complex microbial communities on a single limiting resource
Author
B Kerr
B Momeni
+48Â more
B Sinervo
BH Good
BR Levin
BV Adkar
C Reding-Roman
CK Fisher
E Bairey
F Vasi
FM Stewart
G Hardin
GI Lang
HA Verhoef
HL Smith
I Billick
I Levin-Reisman
J Baranyi
J Baranyi
J Friedman
J Grilli
J Warringer
JF Crow
JM Fitzsimmons
JN Jasmin
JT Wootten
K Faust
LM Chevin
M Manhart
M Novak
M Zackrisson
ME Power
MH Zwietering
MM Mayfield
N Ziv
N Ziv
P Chesson
PE Turner
RC MacLean
RL Buchanan
S Sunagawa
S Widder
SA Levin
SF Levy
SP Hubbell
T Pfeiffer
The Human Microbiome Project Consortium..
V Bucci
Y Himeoka
Z Frentz
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
Deep mutational scanning: a new style of protein science
Author
A Ernst
AM Dean
+51Â more
AM Freeman
ANH Creager
BC Dickinson
BP Roscoe
BV Adkar
C Natarajan
CE Tinberg
CL Araya
CL Araya
CM Forsyth
D Melamed
DE Kim
DM Fowler
DM Fowler
Douglas M Fowler
DS Marks
E Procko
F Gnad
GA Millot
GC Lander
GE Gilbert
I Kim
JA Tennessen
JD Bloom
K Chen
KM Schlinkmann
L Brocchieri
L Foit
L Jiang
LM Starita
M Morell
MG Gold
MW Traxlmayr
N Koga
NC Wu
PH Jonson
R Moretti
RN McLaughlin
RT Hietpas
S Bershtein
Stanley Fields
T Hinkley
TA Whitehead
TJ Magliery
TR Wagenaar
V Potapov
VE Gray
W Zhang
X Wang
Y Fujino
Z Aydin
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
The study of the bacteriophage T5 deoxynucleoside monophosphate kinase active site by site-directed mutagenesis
Author
A Lavie
A Ofiteru
+52Â more
A Teplyakov
AYu Skoblov
B Dhaliwal
BV Adkar
C Papworth
D Dreusicke
D Dreusicke
D Topalis
DH Duckworth
G Hible
G. V. Mikoulinskaia
GJ Schlauderer
GS Brush
GV Mikoulinskaia
H Krishnamurthy
H Yan
HJ Müller-Dieckmann
HJ Müller-Dieckmann
J Sambrook
JA Alexandre
K Fukami-Kobayashi
K Scheffzek
KV Antonov
L Kraft
L Zhou
LJ Bello
M Bellinzoni
M Kotaka
MD Daily
MJ Bessman
MM Bradford
N Bucurenci
N Bucurenci
N Guettari
N Ostermann
N Sekulic
P Briozzo
P Briozzo
PY Ke
Q Lu
R Brundiers
R Liu
S. A. Feofanov
S. A. Taran
SF Altschul
T Krell
T Okajima
TW Traut
U Abele
UK Laemmli
Y Li
Yu. S. Skoblov
Publication venue
'Pleiades Publishing Ltd'
Publication date
Field of study
No full text
Crossref
A statistical framework for analyzing deep mutational scanning data
Author
A Melnikov
A Sahoo
+56Â more
AI Podgornaia
Alan F. Rubin
AM Levin
Anthony T. Papenfuss
AR Majithia
B Levitan
BP Roscoe
BV Adkar
C Bank
C Bank
CA Kowalsky
CE Tinberg
CL Araya
CM Forsyth
D Mavor
D Melamed
DM Fowler
DM Fowler
DM Fowler
DM Fowler
Douglas M. Fowler
E Demidenko
E-C Brockmann
EE Wrenbeck
F Spill
GAF Seber
HA Levine
Hannah Gelman
I Kim
IG Denisov
JB Hiatt
JD Bloom
JD Storey
K Dalal
L Jiang
L Jiang
L Rockah-Shmuel
LL Reich
LM Starita
LM Starita
LM Starita
M Borenstein
MA Stiffler
MP Guy
MS Rich
Nathan Lucas
NC Wu
NF Lamour
RL Plackett
RP Patwardhan
RT Hietpas
S Kosuri
S Matuszewski
Sandra M. Bajjalieh
SB Needleman
Terence P. Speed
Publication venue
'Springer Science and Business Media LLC'
Publication date
Field of study
No full text
Crossref
Latent Effects of Hsp90 Mutants Revealed at Reduced Expression Levels
Author
A Toth-Petroczy
AL Hughes
+65Â more
B Futcher
BP Roscoe
BV Adkar
CL Araya
CS Wylie
D Mumberg
D Mumberg
D Picard
D Rennell
DA Drummond
Daniel N. A. Bolon
DE Dykhuizen
DE Dykhuizen
DF Nathan
DM Fowler
E Dekel
EH Kellogg
G Tschumper
G Tschumper
H Kacser
H Kacser
H Kacser
IJ Tsai
J Debartolo
JB Peris
JF Gout
JL King
JN Pitt
KA Borkovich
KA Dill
KA Geiler-Samerotte
KB Zeldovich
Konstantin B. Zeldovich
KS Zaret
L Whitesell
Li Jiang
M Hegreness
M Lunzer
M Lunzer
M Lynch
M Manceau
MC King
MM Ali
MZ Li
N Tokuriki
N Wayne
N Wayne
NW Pursell
P Carrasco
P Domingo-Calap
Parul Mishra
R Heinrich
R Hietpas
R Sanjuan
RN McLaughlin Jr
RT Hietpas
RT Sauer
Ryan T. Hietpas
S Bershtein
S Henikoff
SF Harris
TA Whitehead
Tricia R. Serio
WP Stemmer
Z Yang
Publication venue
'Public Library of Science (PLoS)'
Publication date
Field of study
No full text
Crossref
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