38 research outputs found
Avaliação do desenvolvimento larval de Anopheles darlingi criado em laboratório sob diferentes dietas Evaluation of the larval development of Anopheles darlingi (Diptera - Culicidae) raised in the laboratory on different diets
São testadas três dietas para larvas de A. darlingi, buscando-se os seguintes parâmetros indicativos de desenvolvimento nesta fase: tempo de evolução total e de cada estádio, sobrevivência ao estádio, diária e total. A metodologia utilizada na determinação desses parâmetros constitui-se da combinação de dois métodos de análise da estatística vital, adaptados ao estudo de populações mantidas em laboratório. Os tempos de evolução total e de cada estádio foram determinados gráficamente a partir das curvas de tendência dos estádios medianos da colônia, em inspeções sucessivas. Os valores de sobrevivência diária, ao estádio e total foram calculados a partir de tábuas de sobrevivência. Os resultados permitiram eleger a dieta composta de uma parte de farinha de peixe para duas partes de farinha de pão e duas partes de germe de trigo como a mais adequada ao desenvolvimento larval, com duração de 12,9 dias entre o primerio estádio e a emersão do adulto e sobrevivência total de 95%.<br>Three diets for A. darlingi larvae were tested in order to arrive at the following parameters indicative of development in this phase: length of time, both for overall as for each stage of evolution and daily and total stage-survival. A methodology which combined two vital statistical methods of analysis, adjusted to the study of populations under laboratory conditions, was used for determining these parameters. The length of time for overall and for each stage of, evolution were graphically assessed on the basis of trend curves of colony median stages, in sequential surveys. Values for the total and the daily stage-survival were stimated from survival tables. Results permitted the selection of the most adequate diet for the larval development as that composed of one part of fish flour to two parts of bread flour and two parts of a heat germ, giving an average length of 12.9 days between the first larval stage and the emergent adult. Total survival rate was of 95%
Relative tachycardia compensating for a small stroke volume contributes to the coronary reserve reduction in hypertensive patients with left ventricular concentric remodeling
Exercise tolerance is depending directly on coronary reserve and inversely on rate-pressure product response to exercise in hypertensive patients without myocardial ischemia.
Relazione fra riserva coronarica e geometria ventricolare sinistra nell’ipertensione arteriosa
Relation of myocardial fibrosis to left ventricular mass and circulating aldosterone and endothelin in human hypertension
Abnormal coronary microcirculatory resistance is already present in borderline high blood pressure
.: Relation of myocardial fibrosis to circulating aldosterone and endothelin in primary and secondary human hypertension: an ultrasonic study by acoustic densitometr
Myocardial ultrasonic backscatter in hypertension. Relation to aldosterone and endothelin
A disproportionate accumulation of fibrillar collagen is a characteristic feature of hypertensive heart disease, but
the extent of myocardial fibrosis may differ in different models of hypertension. In experimental studies, aldosterone and
endothelins emerge as important determinants of myocardial fibrosis. Changes in myocardial extracellular matrix and
collagen deposition can be estimated noninvasively by analysis of the ultrasonic backscatter signal, which arises from
tissue heterogeneity within the myocardium and describes myocardial texture. This study was designed to investigate
the relations between myocardial integrated backscatter and circulating aldosterone and immunoreactive endothelin in
human hypertension. The study population consisted of 56 subjects: 14 healthy normotensive volunteers and 42
hypertensive patients (14 with primary aldosteronism, 7 with renovascular hypertension, and 21 with essential
hypertension). The patients with essential and secondary hypertension were matched for age, gender, body mass index,
and blood pressure. Myocardial integrated backscatter at diastole was 19.82.0 and 20.82.9 decibels in normotensive
control subjects and patients with essential hypertension and significantly higher in patients with primary aldosteronism
(27.43.8 decibels, P0.01) and renovascular hypertension (26.84.8 decibels, P0.01). In the population as a whole,
as well as in the hypertensive subpopulation, myocardial integrated backscatter was directly related to plasma
aldosterone (r0.73 and 0.71, P0.01 for both) and immunoreactive endothelin (r0.60 and 0.56, P0.01 for both).
The data of this study suggest that in human hypertension, circulating aldosterone and immunoreactive endothelin may
induce alterations in left ventricular myocardial texture, possibly related to increased myocardial collagen content