45 research outputs found

    5-Lipoxygenase Metabolic Contributions to NSAID-Induced Organ Toxicity

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    Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo

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    Despite the growing number of binary black hole coalescences confidently observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include the effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that have already been identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total source-frame mass M > 70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz emitted gravitational-wave frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place a conservative upper limit for the merger rate density of high-mass binaries with eccentricities 0 < e ≤ 0.3 at 16.9 Gpc−3 yr−1 at the 90% confidence level

    Open data from the third observing run of LIGO, Virgo, KAGRA, and GEO

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    The global network of gravitational-wave observatories now includes five detectors, namely LIGO Hanford, LIGO Livingston, Virgo, KAGRA, and GEO 600. These detectors collected data during their third observing run, O3, composed of three phases: O3a starting in 2019 April and lasting six months, O3b starting in 2019 November and lasting five months, and O3GK starting in 2020 April and lasting two weeks. In this paper we describe these data and various other science products that can be freely accessed through the Gravitational Wave Open Science Center at https://gwosc.org. The main data set, consisting of the gravitational-wave strain time series that contains the astrophysical signals, is released together with supporting data useful for their analysis and documentation, tutorials, as well as analysis software packages

    Análise de equações preditivas da gordura corporal em jovens atletas de "taekwondo"

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    Devido à falta de métodos acessíveis válidos para mensurar o percentual de gordura corporal (%G) de taekwondistas adolescentes (TKDA), objetivou-se analisar seis equações antropométricas de predição do %G, em cinco TKDA (12,23 anos ± 1,60), utilizando como método de referência a Densitometria Radiológica de Dupla Energia (DEXA). Os %G estimados pelas equações foram comparados pelo teste t-student, regressão linear e Bland e Altman (B&A) com os obtidos por DEXA. Apenas a equação de Slaughter et al. (1988) foi adequada pelo cálculo amostral, e embora tenha subestimado o %G (em 4,85% ± 0,98), esta apresentou alta correlação (R = 0,935; R² = 0,874 EPE = 1,01) e baixa amplitude nos limites de concordância a 95% (3,84%) pelo B&A em comparação com a DEXA. Portanto, esta equação mostrou-se adequada para a predição do %G em TKDA, desde que seja corrigida pela equação de ajuste [%G (DEXA) = 1,64 + 1,24 &#8226; %G (Eq 4)] gerada pela regressão linear.Debido a la falta de métodos accesibles válidos para medir el porcentaje de grasa del cuerpo (%G) de atletas de taekwondo adolescentes (TKDA), destinada a analizar seis ecuaciones antropométricas de predicción de %G, en cinco TKDA (12,23 años ± 1,60 ), utilizando como método de referencia la Densitometría Radiológica de Energía Dual (DEXA). El %G estimado por las ecuaciones fue comparado mediante la prueba t-student, regresión lineal y Bland & Altman (B&A) con los que se obtienen mediante DEXA. Sólo la ecuación del SLAUGHTER et al. (1988) fue adecuada para el cálculo del tamaño de la muestra y, a pesar de que había subestimado la %G (4,85 % ± 0,98 ), este mostró una alta correlación (R = 0,935 ; R2 = 0,874 EPE = 1,01 ) y baja amplitud dentro de los límites de concordancia con el 95% (3,84 %) por B&A en comparación con la DEXA. Por lo tanto, esta ecuación demostró ser adecuada para la predicción de %G en TKDA, desde que corrigida mediante la siguiente ecuación de ajuste [ %G (DEXA) = 1,64 + 1,24 &#8226; %G (eq 4)] generada mediante regresión lineal.Due to the lack of valid and accessible tests to measure the body fat percentage (BF%) of adolescent taekwondo athletes (TKDA), this study aimed to analyze six anthropometric equations in the prediction of BF% with the Dual-Energy-x-Ray (DEXA) as referential method for five TKDA (12.23 years ± 1.60). The BF% estimated by the equations were compared with DEXA values using the t-student , linear regression and Bland & Altman (B&A) tests. Only the equation of Slaughter et al. (1988) was adequated by the sample size calculation, and although it subestimated the BF% (in 4.85% ± 0.98), it showed a high correlation (R = 0.935; R² = 0.874 EPE = 1.01) and low amplitude in the limits of agreement at 95% (3.84%) by B&A in comparison to DEXA. However, this equation is adequated to predict the BF% in TKDA, if it's corrected by the adjustement equation [%G (DEXA) = 1,64 + 1,24&#8226;%G (Eq 4)] generated by linear regression

    Efficacy of anatomical prostheses in primary glenohumeral osteoarthritis

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    More than 32.8% of the over-60s suffer from shoulder osteoarthritis. For advanced osteoarthritis, arthroplasty is the treatment of choice. Current systems have moved on from the first shoulder prosthesis implanted by Neer in 1974, thanks to the use of adaptable modular systems. The aim of this study was to investigate the effectiveness of anatomical shoulder replacements in 30 cases of primary glenohumeral osteoarthritis through clinical and radiographic follow-up for a mean of 5 years. All implants were total cemented prostheses. Preoperative investigations included a clinical examination, conventional X-rays and CT. The Constant-Murley scale was used to evaluate the results; the mean score increased from 21.4 preoperative to 69.8 postoperative (p<0.05). In patients aged under 50, the increase in the mean postoperative Constant Score and ROM was greater than for the sample as a whole. The following complications were encountered: 2 postoperative radial nerve paralyses, resolving in 3 months, 2 cases of glenoid loosening, 1 periprosthetic fracture and 3 cases of pain and stiffness. The results led us to conclude that anatomical prostheses are effective in the treatment of severe primary glenohumeral arthropathy
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