Potential causes of mortality for horseshoe crabs (Limulus polyphemus) during the biomedical bleeding process

Biomedical companies catch and bleed horseshoe crabs for the production of Limulus amebocyte lysate (LAL), a product used for protecting public health (Berkson and Shuster, 1999). LAL is a clotting agent, derived solely from horseshoe crab blood cells, which is used to detect the presence of pathogenic gramnegative bacteria in injectable drugs and implantable medical and dental devices (Mikkelsen, 1988; Novitsky, 1991). In addition, LAL is used in many diagnostic tests for such illnesses as gram-negative bacterial meningitis and typhoid fever (Ding and Ho, 2001). Because the LAL test allows one to detect femtogram levels of endotoxin (Ding and Ho, 2001), it is the most effective test for detecting endotoxin contamination, and its increasing use in medical and pharmaceutical laboratories makes it a highly valued product

A production modeling approach to the assessment of the horseshoe crab (Limulus polyphemus) population in Delaware Bay

Horseshoe crab (Limulus polyphemus) is harvested commercially, used by the biomedical industry, and provides food for migrating shorebirds, particularly in Delaware Bay. Recently, decreasing crab population trends in this region have raised concerns that the stock may be insufficient to fulfill the needs of these diverse user groups. To assess the Delaware Bay horseshoe crab population, we used surplus production models (programmed in ASPIC), which incorporated data from fishery-independent surveys, fishery-dependent catch-per-unit-of-effort data, and regional harvest. Results showed a depleted population (B2003/=0.03−0.71) BMSY and high relative fishing mortality /FMSY=0.9−9.5). Future harvest (F2002strategies for a 15-year period were evaluated by using population projections with ASPICP software. Under 2003 harvest levels (1356 t), population recovery to BMSY would take at least four years, and four of the seven models predicted that the population would not reach BMSY within the 15year period. Production models for horseshoe crab assessment provided management benchmarks for a species with limited data and no prior stock assessmen

Truth as an evaluative, semantic property: a defence of the linguistic priority thesis

Thinking and using a language are two different but similar activities. Thinking about thinking and thinking about language use have been two major strands in the history of philosophy. One of the principal similarities is that they are both rational activities. As a result, the ability to think and the ability to use a language require being able to recognise and respond to reasons. However, there is a further feature of these activities: we humans are able to have explicit knowledge of how those activities work and what is done by performances in those activities. Thus, theorists face at least two constraints: 1. An account of a rational activity must be compatible with the possibility of agents engaging in that activity. 2. Having described an activity, it must be possible to have knowledge of an activity which is correctly described like that. There are a variety of accounts of how thinking works and how using a language works, and further variation in accounts of what is involved in explicit understanding of particular performances. These accounts can be distinguished by their views of the nature of the reasons that govern performances in that activity and by their views of the way a description of the activity relates to the way the activity proceeds. I argue that any description of thinking or language use requires showing how the truth conditions of thoughts/sentences are determined, and how the truth values of thoughts/sentences affects the way the activity proceeds. I then argue that in order to have explicit knowledge of what we do, truth has to be a substantial evaluative property of uses of language, and furthermore a truth conditional theory of meaning has to be taken as the description of the rationality of using a language. The big result is that, because in understanding language we understand truth, the philosophy of language is first philosophy

Production, Perception, and Distribution of Breathy Sonorants in Marathi

Breathy sonorants are crosslinguistically rare, and while a small amount of existing work has focused on their acoustic properties much remains to be learned about their perception and their language-internal distribution. Herein, breathy sonorants in Marathi are investigated via instrumental acoustic analysis, a perception experiment, and corpus analysis. Results reveal that breathy sonorants are under-represented language-internally in addition to being typologically rare. The acoustic differences associated with sonorant phonation contrasts are less robust than those in obstruents. They are also prone to more perception errors than obstruents, and breathy sonorants are more heavily restricted phonotactically than breathy obstruents. These data contribute to a more nuanced understanding of breathy sonorants, and lend potential insight into their typology.

c-Myc induced changes in higher order rDNA structure accompany growth factor stimulation of quiescent cells

Human c-Myc is believed to be a high level coordinator of protein synthesis capacity and cell growth rate, capable of activating transcription by all three nuclear RNA Polymerases. Direct activation of rDNA transcription by c-Myc is functionally conserved in rat cells, despite high divergence in non-coding rDNA sequences, suggesting that this coordinating role is likely to be a general within mammals. Upon re-feeding of starved cells, c-Myc activity enhances the efficiency of RNA Polymerase I and SL1/TIF-1B recruitment to the rDNA and rapidly induces higher order gene loop structures in rDNA chromatin that juxtapose upstream and downstream rDNA sequences. Furthermore c-Myc induced gene-loop formation in rDNA genes occurs independently of rDNA transcription, implying that it may be an early step in the re-programming of quiescent cells as they enter the growth cycle

The Language of Democracy, Xenophobia, and the Rise of the Far Right in France and Spain After the 2015 Migration Crisis

This thesis examines the relationship between immigration and far right-wing popularity in Europe, specifically France and Spain after the 2015 migration crisis. Comparing data from several European Union countries after 2015, a pattern is identified that when immigration increased, so did the representation of far right-wing parties. This thesis then details a nuanced analysis of two case studies, and the underlying reasons why far right-wing parties gained popularity in France and Spain. This thesis also examines the roots of present-day democracy in France and Spain, and how they contribute to current social understandings of national identity, which have led to increases in xenophobia in France and Spain which far right-wing parties have benefitted from. To conclude, this thesis also offers insight into why this trend might be a warning of a larger European issue of a backlash against an increasingly multicultural Europe

Vitis vulpina L.

https://thekeep.eiu.edu/herbarium_specimens_byname/19465/thumbnail.jp

Morus rubra L.

https://thekeep.eiu.edu/herbarium_specimens_byname/20053/thumbnail.jp

Morus rubra L.

https://thekeep.eiu.edu/herbarium_specimens_byname/20053/thumbnail.jp