The diagnostic and prognostic value of red cell distribution width in cardiovascular disease, current status and prospective

The red blood cell distribution width (RDW) is an index of the heterogeneity of circulating red blood cell size, which along with other standard complete blood count (CBC) parameters are used to identify hematological system diseases. Besides hematological disorders, several clinical studies have shown that an increased in the RDW may be associated with other diseases including acute pancreatitis, chronic kidney disease, gastrointestinal disorders, cancer, and of special interest in this review, cardiovascular disease (CVD). The diagnostic and prognostic value of RDW in different CVD (acute coronary syndrome, ischemic cerebrovascular disease, peripheral artery disease, atrial fibrillation, heart failure, and acute ischemic stroke) has been reviewed in this article, to provide an understanding how its measurement may be applied to improve the management of these conditions.Keywords: RDW, Biomarker, Cardiovascular disease

Seismogenic zones in eastern Turkey

An edited version of this paper was published by the American Geophysical Union (AGU). Copyright 2003, AGU. See also: http://www.agu.org/pubs/crossref/2003.../2003GL018023.shtml; http://atlas.geo.cornell.edu/turkey/publications/Turkelli-et-al_2003.htmA 29-station temporary broadband PASSCAL network was operated from late October 1999 to August 2001 in eastern Turkey in order to decipher the geodynamics of one of the youngest continent-continent collision zones in the world. This paper focuses on the hypocentral distribution of local earthquakes located during the operation of the network and provides new insights into the active faulting in the Anatolian plateau. A total of 1165 earthquakes were located and classified into four different categories based on the reliability of the locations as established by the data coverage. The accuracy of the locations ranked in the best two categories is estimated to be less than approximately 5 km. The results show that seismic activity in Eastern Turkey is higher than previously documented and there were no subcrustal earthquakes beneath the Arabian- Eurasian collision zone or beneath the Anatolian plateau during our deployment. This result suggests no or very little underthrusting of the Arabian plate beneath Eurasia. Our results also suggest that the North Anatolian Fault zone extends farther toward the southeast, well beyond the Karliova triple junction, and that a number of unmapped active, seismogenic faults exist in the region. We also observed a possible difference in the seismogenic thickness of the East Anatolian fault zone (EAFZ) and the North Anatolian fault zone (NAFZ)

Chlamydial infections in term and preterm neonates

PubMed ID: 22274150The aim of this study was to evaluate the incidence and morbidities of Chlamydia trachomatis infections in newborn infants. Tissue culture and direct immunofluorescence (DIF) tests were used to detect the presence of nasopharyngeal C. trachomatis infection in 35 pretermand 21 healthy termneonates. All infants were followed up clinically for 3 months, and enzyme-linked immunosorbent assay analysis for serum antichlamydial IgG and IgM was performed on day 15 and week 6. Tissue culture and/or DIF studies showed that 10 of the preterm infants (28.57z), but none of the term infants, were C. trachomatis-positive. The sensitivities of DIF and tissue culture were 40z and 70z, respectively, demonstrating the diagnostic superiority of tissue culture tests for detecting C. trachomatis. Only one asymptomatic preterm infant was found to be positive for antichlamydial antibodies at the 6th week. All C. trachomatis-positive infants were given macrolide antibiotics for 14 days. The study showed that male infants were more frequently infected, but types of delivery, mean gestational ages, mean birth weights, and the need for mechanical ventilation were similar in C. trachomatis-infected and uninfected preterm infants. However, the duration of oxygen treatment was longer in infected preterm infants. Clinical conjunctivitis was more frequent in C. trachomatis-infected infants (60z) than in uninfected infants (24z). C. trachomatis-positive infants had pneumonia more frequently; however, all patients with pneumonia were negative for antichlamydial IgM and IgG antibodies. Macrolide treatment for 2 weeks for nasopharyngeal C. trachomatis positivity may have prevented C. trachomatis related pneumonia, but it may not have significantly influenced the risk of pneumonia caused by other agents. Chlamydial infections may lead to early and late respiratory problems in preterm infants. Nasopharyngeal screening may help physicians detect C. trachomatis infections and provide a means of early diagnosis in this vulnerable patient group

Seismic event location using the Eastern Turkey Seismic Network: Analysis of the Agri Dam explosion

Copyright 2004, Seismological Society of America. See also: http://www.seismosoc.org/publications/bssa-toc.html; http://atlas.geo.cornell.edu/turkey/publications/Gurbuz-et-al_2004.htmA 12 ton controlled source explosion took place in eastern Turkey on June 5, 2001 and was recorded by 18 stations of the Eastern Turkey Seismic Experiment (ETSE) PASSCAL broadband network. This is a unique recording obtained for the first time in this region. Due to the blasting type and extremely high Lg and Sn attenuation in eastern Turkey, the blast is only observed out to a distance of about 300 km. We have used travel time data from this explosion to obtain average crustal structure and site correction terms for the stations. The explosion was located using two new regional velocity models and the IASP91 velocity model to test the location capabilities of the ETSE network. We found that for surface focus events, the ETSE network is able to locate events to within 1 - 2 km of the true epicenter

Does bone impaction technique reduce tunnel enlargement in ACL reconstruction?

The aim of this study was to investigate effects of bone impaction technique on tunnel enlargement after ACL reconstruction at a minimum 2 years follow-up. Two groups of patients who had been operated upon with the same arthroscopic technique with the exception of tibial tunnel constitution were compared. Twenty-one patients of group A (drilling to 6 mm followed enlargement to 8–9 mm by using dilators) and 23 patients of group B (directly drilling to the size of the graft) were evaluated clinically and radiographically based on multislice computerised tomography (MSCT) retrospectively. At follow-up, there was no statistical difference between tunnel diameters between two groups at the femoral site, but significant difference at the tibial site (p = 0.00192 for coronal; p = 0.0171 for sagittal diameter). Both groups were comparable according pre- and postoperative Lysholm and IKDC scores (p < 0.5 Mann-Whitney U test). Compacted tunnel walls may resist enlargement, suggesting this technique resulted in better tunnel diameter values especially with intratunnel fixation