Minimally displacive impression technique: A clinical report

Management of edentulous ridges with localized hyperplastic tissue is challenging. This clinical report describes the treatment of a completely edentulous patient with localized hyperplastic alveolar ridges. A modified impression technique was used to optimize the treatment of edentulous patient with ‘flabby’ alveolar ridges in which surgical preparation of the mouth was contraindicated to meet the functional and psychological needs of the patient. Thereby the treatment described has simplified the management of a historically complex problem

Analysis of the properties of commercially available silicone elastomers for maxillofacial prostheses

 Aim - Maxillofacial prosthetic materials are used to replace facial parts lost through disease or trauma. Silicone rubbers are the materials of choice. The aim of this study was to assess the properties of three new silicone rubber maxillofacial materials. Methods- Specimens of three commercially available maxillofacial materials were prepared in dental flasks according to manufacturers’ instructions. Tear strength, tensile strength, percentage elongation, hardness and water absorption were determined for each material. Result- Cosmesil high compliance had significantly higher tear strength than other materials and tensile strength was also higher than the other materials but not statistically significant. Hardness and percentage elongation were almost same for all the materials. Prestige elastomer had higher water absorption than the other two materials, but it was not statistically significant. Conclusion- None of the commercially available silicone rubber materials possessed ideal properties for use as a maxillofacial prosthetic material but within the limitations of present study, Cosmesil high compliance shows more favourable properties among the three materials. Key words- silicone rubber, maxillofacial prosthesis, mechanical properties,tear strength, hardness, water absorption

Three-component reaction of a δ-hydroxy-α,β-unsaturated aldehyde with arylamines and 1,3-diketones: a novel synthesis of oxa-aza bicycles

δ-Hydroxy-α,β-unsaturated sugar aldehydes (Perlin aldehydes) undergo smooth coupling with β-enamino ketones and β-enamino esters generated in situ from arylamines and 1,3-dicarbonyl compounds in the presence of 10 mol% InCl<SUB>3</SUB> in acetonitrile at 80°C, to produce oxa-aza-bicycles in good yields with high selectivity

Pd(OAc)<SUB>2</SUB>-catalyzed C-H activation of indoles: a facile synthesis of 3-cyanoindoles

Indoles undergo smooth cyanation with CuCN in the presence of 20 mol % Pd(OAc)2 and 40 mol % CuBr2 in DMF to produce a wide range of the corresponding 3-cyanoindoles in good yields with high regioselectivity

Indium(III) chloride catalyzed, novel and efficient synthesis of sugar-annulated N-aryltetrahydropyridines

δ-Hydroxy-α,β-unsaturated aldehydes undergo smooth coupling with enamines derived from arylamines and 1,3-diketones in the presence of 10% InCl<SUB>3</SUB> in CH<SUB>2</SUB>Cl<SUB>2</SUB> under mild reaction conditions to afford sugar fused N-aryltetrahydropyridine derivatives in good yields with high selectivity. The salient features of this method are high conversions, mild reaction conditions, short reaction times, high selectivity and operational simplicity

Catalytic Efficiency of Primary &alpha;-Amino Amides as Multifunctional Organocatalysts in Recent Asymmetric Organic Transformations

Chiral primary &alpha;-amino amides, consisting of an adjacent enamine bonding site (Bronsted base site), a hydrogen bonding site (Bronsted acid site), and flexible bulky substituent groups to modify the steric factor, are proving to be extremely valuable bifunctional organocatalysts for a wide range of asymmetric organic transformations. Primary &alpha;-amino amides are less expensive alternatives to other primary amino organocatalysts, such as chiral diamines and cinchona-alkaloid-derived primary amines, as they are easy to synthesize, air-stable, and allow for the incorporation of a variety of functional groups. In recent years, we have demonstrated the catalytic use of simple primary &alpha;-amino amides and their derivatives as organocatalysts for the aldol reaction, Strecker reaction, Michael tandem reaction, allylation of aldehydes, reduction of N-Aryl mines, opening of epoxides, hydrosilylation, asymmetric hydrogen transfer, and N-specific nitrosobenzene reaction with aldehydes