5 research outputs found
The transition from intra to extra-uterine life in late preterm infant: a single-center study
Tailoring the interaction with users in electronic shops
Abstract. We describe the user modeling and personalization techniques adopted in SETA, a shell supporting the construction of adaptive Web stores which customize the interactions with users, suggesting the items best fitting their needs, and adapting the description of the store catalog to their preferences and expertise. SETA uses stereotypical information to handle the user models and applies personalization rules to dynamically generate the hypertextual pages presenting products: the system adapts the graphical aspect, length and terminology used in the descriptions to the user’s receptivity, expertise and interests. Moreover, it maintains a profile associated to each person the goods are selected for, to provide multiple criteria for the selection of items, tailored to the beneficiaries ’ preferences.
Activated microglia mediate synapse loss and short-term memory deficits in a mouse model of transthyretin-related oculoleptomeningeal amyloidosis
NSC39691
Studies of psychiatric disorders have traditionally focused on emotional symptoms such as depression, anxiety and hallucinations. However, poorly controlled cognitive deficits are equally prominent and severely compromise quality of life, including social and professional integration. Consequently, intensive efforts are being made to characterize the cellular and cerebral circuits underpinning cognitive function, define the nature and causes of cognitive impairment in psychiatric disorders and identify more effective treatments. Successful development will depend on rigorous validation in animal models as well as in patients, including measures of real-world cognitive functioning. This article critically discusses these issues, highlighting the challenges and opportunities for improving cognition in individuals suffering from psychiatric disorders