Neutral perfect fluids of Majumdar-type in general relativity

We consider the extension of the Majumdar-type class of static solutions for the Einstein-Maxwell equations, proposed by Ida to include charged perfect fluid sources. We impose the equation of state $\rho+3p=0$ and discuss spherically symmetric solutions for the linear potential equation satisfied by the metric. In this particular case the fluid charge density vanishes and we locate the arising neutral perfect fluid in the intermediate region defined by two thin shells with respective charges $Q$ and $-Q$. With its innermost flat and external (Schwarzschild) asymptotically flat spacetime regions, the resultant condenser-like geometries resemble solutions discussed by Cohen and Cohen in a different context. We explore this relationship and point out an exotic gravitational property of our neutral perfect fluid. We mention possible continuations of this study to embrace non-spherically symmetric situations and higher dimensional spacetimes.Comment: 9 page

Animal models for COVID-19

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the introduction of a novel coronavirus into humans late in 2019 (first detected in Hubei province, China). As of 18 September 2020, SARS-CoV-2 has spread to 215 countries, has infected more than 30 million people and has caused more than 950,000 deaths. As humans do not have pre-existing immunity to SARS-CoV-2, there is an urgent need to develop therapeutic agents and vaccines to mitigate the current pandemic and to prevent the re-emergence of COVID-19. In February 2020, the World Health Organization (WHO) assembled an international panel to develop animal models for COVID-19 to accelerate the testing of vaccines and therapeutic agents. Here we summarize the findings to date and provides relevant information for preclinical testing of vaccine candidates and therapeutic agents for COVID-19

Embryogenesis: Pattern Formation from a Single Cell

During embryogenesis a single cell gives rise to a functional multicellular organism. In higher plants, as in many other multicellular systems, essential architectural features, such as body axes and major tissue layers are established early in embryogenesis and serve as a positional framework for subsequent pattern elaboration. In Arabidopsis, the apicalbasal axis and the radial pattern of tissues wrapped around it are already recognizable in young embryos of only about a hundred cells in size. This early axial pattern seems to provide a coordinate system for the embryonic initiation of shoot and root. Findings from genetic studies in Arabidopsis are revealing molecular mechanisms underlying the initial establishment of the axial core pattern and its subsequent elaboration into functional shoots and roots. The genetic programs operating in the early embryo organize functional cell patterns rapidly and reproducibly from minimal cell numbers. Understanding their molecular details could therefore greatly expand our ability to generate plant body patterns de novo, with important implications for plant breeding and biotechnology