148 research outputs found
On roughness measurement by angular speckle correlation
In this work, the influence of both characteristics of the lens and misalignment of the incident beams on roughness measurement is presented. To investigate how the focal length and diameter affect the degree of correlation between the speckle patterns, a set of experiments with different lenses is performed. On the other hand, the roughness when the beams separated by an amount are non-coincident at the same point on the sample is measured. To conclude the study, the uncertainty of the method is calculated
First dose behavioral tolerance to phencyclidine on food-rewarded bar pressing behavior in the rat
The behavioral effects of single doses of phencyclidine (PCP) were examined in drug-naive adult male Holtzman rats trained to press a bar on a fixed ratio (4) schedule (FR 4 ), i.e., a reward of sugarsweetened milk was earned on every fourth bar press. Groups of rats (four to eight rats per group) received specific doses of PCP which were held constant for each group throughout the study. Dose-response curves for PCP given in doses of 1.0, 1.8, 2.4, and 3.2 mg/kg IP were first determined and then redetermined at weekly intervals. A drug-free interval of 7â8 days was maintained between injections given weekly over a period of 4 weeks. The final dose of PCP was administered after a 4-week drug-free period. Evidence was obtained for first dose behavioral tolerance as shown by the significantly shortened duration of suppression of bar pressing on subsequent injections. Although subsequent weekly effects of equal doses of PCP showed no significant differences, they all differed significantly from the first injection. The reduced response to PCP was shown to be due to learned behavioral tolerance as demonstrated when PCP (3.2 mg/kg IP) was given to drug-naive animals in their home cages and 1 week later given the second dose in the operant behavioral situation. Under these circumstances, the second dose of PCP showed a similarly protracted depression of FR 4 responding as other animals given the drug for the first time in the operant situation. Subsequent weekly injections in the operant situation produced similar behavioral tolerance.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46412/1/213_2004_Article_BF00426513.pd
Effects of selected opioid agonists and antagonists on DMT-and LSD-25-induced disruption of food-rewarded bar pressing behavior in the rat
Several opioid agonists and antagonists interact with N,N-dimethyltryptamine (DMT) and lysergic acid diethylamide-25 (LSD) in adult male Holtzman rats trained on a positive reinforcement, fixed ratio 4 (FR 4 ) behavioral schedule, i.e., a reward of 0.01 ml sugar-sweetened milk was earned on every fourth bar press. DMT (3.2 and 10.0 mg/kg) and LSD (0.1 mg/kg) given IP with 0.9% NaCl pretreatment, disrupted food-rewarded FR4 bar pressing. Animals were pretreated IP (10â15 min) with predetermined, behaviorally noneffective doses of morphine, methadone, naltrexone, and the (+)-and (-)-enantiomers of naloxone prior to receiving DMT or LSD. Dose-dependent effects were shown with opioid agonist pretreatment. Morphine (0.32â1.0 mg/kg) and methadone (0.32 mg/kg) significantly antagonized the bar pressing disruption induced by DMT and LSD. Larger doses of morphine (3.2 mg/kg) and methadone (1.0â3.2 mg/kg) potentiated only LSD-induced effects, with no effect on DMT-treated groups. The opioid antagonists (-)-naloxone and naltrexone potentiated the disruption of bar pressing induced by DMT and LSD. Failure of (+)-naloxone to potentiate the DMT effects was attributed to a stereospecific opioid antagonist effect of (-)-naloxone.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46425/1/213_2004_Article_BF00432428.pd
An airdrop that preserves recipient privacy
A common approach to bootstrapping a new cryptocurrency is an airdrop,
an arrangement in which existing users give away currency to entice
new users to join. But current airdrops offer no recipient privacy:
they leak which recipients have claimed the funds, and this information
is easily linked to off-chain identities.
In this work, we address this issue by defining a private airdrop and
describing concrete schemes for widely-used user credentials, such
as those based on ECDSA and RSA. Our private airdrop for RSA builds
upon a new zero-knowledge argument of knowledge of the factorization
of a committed secret integer, which may be of independent interest.
We also design a private genesis airdrop that efficiently sends private
airdrops to millions of users at once. Finally, we implement and
evaluate. Our fastest implementation takes 40--180 ms to generate
and 3.7--10 ms to verify an RSA private airdrop signature. Signatures
are 1.8--3.3 kiB depending on the security parameter
Cyanobacterial nitrogenases: phylogenetic diversity, regulation and functional predictions
Analysis of carbohydrate storage granules in the diazotrophic cyanobacterium Cyanothece sp. PCC 7822
Nonstandard finite difference variational integrators for nonlinear Schrödinger equation with variable coefficients
The devil lies in the definition: competing approaches to fossil fuel subsidies at the IMF and the OECD
Legitimacy intermediation in the multilevel European polity and its collapse in the euro crisis
This essay re-examines the dual â republican and liberal â foundations of democratic legitimacy in the Western traditions of normative political theory. Considered in isolation, the European Union conforms to liberal standards but cannot satisfy republican criteria. Given these conflicting standards, debates on the alleged European democratic deficit have remained inconclusive. Moreover, they have failed to pay sufficient attention to the multilevel character of the European polity and to the normative potential of legitimacy intermediation in its two-step compliance and legitimating relationships. I argue, however, that the capacity of democratic member states to legitimate the exercise of European governing functions is being destroyed in the present euro crisis, and I briefly discuss the implications of this new constellation.In der westlichen Tradition der normativen politischen Theorie beruht demokratische LegitimitĂ€t auf der doppelten Grundlage republikanischer und liberaler Prinzipien. FĂŒr sich betrachtet entspricht die EuropĂ€ische Union zwar liberalen Kriterien, aber eben nicht den republikanischen Anforderungen. Angesichts so unterschiedlicher Kriterien konnte es auch im Streit ĂŒber das angebliche europĂ€ische Demokratiedefizit keine Einigung geben. Ăberdies ignorierte diese Diskussion den Mehrebenen-Charakter der europĂ€ischen Politik und das normative Potenzial der Legitimationsvermittlung zwischen Union und BĂŒrgern durch die demokratisch verfassten Mitgliedstaaten. Die gegenwĂ€rtige Eurokrise allerdings zerstört die FĂ€higkeit demokratischer Mitgliedstaaten, die AusĂŒbung europĂ€ischer Herrschaftsfunktionen zu legitimieren. Der Aufsatz erörtert die Implikationen dieser neuen Konstellation.1 Introduction 2 Legitimacy discourses The republican discourse The liberal discourse Differences 3 Constitutional democracies â and the European Union? 4 Legitimacy intermediation in the multilevel European polity 5 The end of legitimacy intermediation in the euro crisis Monetary Union and the failure of output legitimacy Rescuing the euro through supranational intervention 6 Legitimate supranational government? Input-oriented European legitimacy? 7 Reducing the burden on European legitimacy Reference
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