27 research outputs found

    CleanBGP: Verifying the consistency of BGP data

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    Copyright © 2008 IEEEBGP data contains artifacts introduced by the measurement infrastructure which can substantially affect analysis. This is especially important in operational systems where "crying wolf" will result in an operator ignoring alarms. In this paper, we investigate the causes of measurement artifacts in BGP data - cross-checking and using properties of the data to infer the presence of an artifact and minimize its impact. We have developed a prototype tool, CleanBGP, which detects and corrects the effects of artifacts in BGP data, which we believe should be used prior to the analysis of such data. CleanBGP provides the user with an understanding of the artifacts present, a mechanism to remove their effects, and consequently the limitations of results can be fully quantified.Ashley Flavel, Olaf Maennely, Belinda Chiera, Matthew Roughan and Nigel Bea

    Untersuchungen der von Tumornekrosefaktor und verwandten Zytokinen abhaengigen Schutzmechanismen in der experimentellen Sepsis Schlussbericht

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    We demonstrated in the experimental sepsis model of cecal ligation and puncture (CLP) that TNF is essential for survival. The TNF required for protection acts via the p55TNF receptor as shown in experiments using TNF receptor-deficient mice. Pretreatment with IL-12 or injection of IFN#gamma# at the time of CLP rendered mice extremely sensitive for the lethal outcome of CLP. Experiments with mast cell-deficient mice have shown that mast cells are an ideal TNF source since they are capable of quickly providing stored TNF at the site of infection. The protective mechanism of TNF includes recruitment of granulocytes into the peritoneal cavity and their activation as well as generation of fibrin depositions for localization of the septic focus. These mechanisms of innate immunity are extremely important reactions of the organism for survival of septic peritonitis. (orig.)SIGLEAvailable from TIB Hannover: DtF QN1(67,30) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman
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