15 research outputs found
Relativistic mass distribution in event-anti-event system and ``realistic'' equation of state for hot hadronic matter
We find the equation of state which gives the value of
the sound velocity in agreement with the ``realistic'' equation of
state for hot hadronic matter suggested by Shuryak, in the framework of a
covariant relativistic statistical mechanics of an event--anti-event system
with small chemical and mass potentials. The relativistic mass distribution for
such a system is obtained and shown to be a good candidate for fitting hadronic
resonances, in agreement with the phenomenological models of Hagedorn, Shuryak,
{\it et al.} This distribution provides a correction to the value of specific
heat 3/2, of the order of 5.5\%, at low temperatures.Comment: 19 pages, report TAUP-2161-9
Chromomagnetic Catalysis of Color Superconductivity in a (2+1)-dimensional NJL Model
The influence of a constant uniform external chromomagnetic field on the
formation of color superconductivity has been investigated. The consideration
was performed in the framework of a (2+1)-dimensional Nambu--Jona-Lasinio model
with two different four-fermionic structures responsible for condensates. In particular, it was shown that there exists a
critical value of the external chromomagnetic field such that at
a nonvanishing diquark condensate is dynamically created (the so-called
chromomagnetic catalysis effect of color superconductivity). Moreover, external
chromomagnetic fields may in some cases enhance the diquark condensate of color
superconductivity.Comment: 32 pages, 2 figures, revte
Tumour acidosis: from the passenger to the driver's seat.
The high metabolic demand of cancer cells leads to an accumulation of H(+) ions in the tumour microenvironment. The disorganized tumour vasculature prevents an efficient wash-out of H(+) ions released into the extracellular medium but also favours the development of tumour hypoxic regions associated with a shift towards glycolytic metabolism. Under hypoxia, the final balance of glycolysis, including breakdown of generated ATP, is the production of lactate and a stoichiometric amount of H(+) ions. Another major source of H(+) ions results from hydration of CO2 produced in the more oxidative tumour areas. All of these events occur at high rates in tumours to fulfil bioenergetic and biosynthetic needs. This Review summarizes the current understanding of how H(+)-generating metabolic processes segregate within tumours according to the distance from blood vessels and inversely how ambient acidosis influences tumour metabolism, reducing glycolysis while promoting mitochondrial activity. The Review also presents novel insights supporting the participation of acidosis in cancer progression via stimulation of autophagy and immunosuppression. Finally, recent advances in the different therapeutic modalities aiming to either block pH-regulatory systems or exploit acidosis will be discussed