2 research outputs found
DENSITOMETRTSCHE UNTERSUCHUNGEN ZUR PHOTOSTABILITÄT VON MELOXICAM
Photodegradation of meloxicam is studied placing special emphasis on the investigation of the correlation between the sample concentration and the stability. For quantitation a HPTLC assay was developed. The stability indicating capability ofthe assay is proved using a sampie solution exposed to artificial irradiation from a xenon source, the peak of meloxicam was weil separated from alldegradation products. For quantitation external calibration is employed. Sample solutions of meloxicam of three different concentrations (2 mg ml-1; 250 μg ml-1 ; 40 μg ml-1) are subjected to simulated sunlight and tested for stability