Effect of the source charge on charged-beam interferometry

We investigate quantal perturbations of the interferometric correlations of charged bosons by the Coulomb field of an instantaneous, charged source. The source charge increases the apparent source size by weakening the correlation at non-zero relative momenta. The effect is strongest for pairs with a small total momentum and is stronger for kaons than for pions of the same momenta. The experimental data currently available are well described by this effect without invoking Pratt's exploding source model. A simple expression is proposed to account for the effect.Comment: 9 pages TEX, 3 Postscript figures available at http://www.krl.caltech.edu/preprints/MAP.htm

The NuMI Neutrino Beam and Potential for an Off-Axis Experiment

The Neutrinos at the Main Injector (NuMI) facility at Fermilab is under construction and due to begin operations in late 2004. NuMI will deliver an intense $\nu_{\mu}$ beam of variable energy 2-20 GeV directed into the Earth at 58 mrad. Several aspects of the design are reviewed, and potential limitations to the ultimate neutrino flux are described. In addition, potential measurements of neutrino mixing properties are described.Comment: talk given at NuFact '02, Imperial College London, proceedings to appear in J. Phys. G, revised to add a referenc

Gene Discovery and Functional Genomics in the Pig

Advances in gene mapping and genomics in farm animals have been considerable over the past decade. Medium resolution linkage and physical maps have been reported, and specific chromosomal regions and genes associated with traits of biological and economic interest have been identified. We have reached an exciting stage in gene identification, mapping and quantitative trait locus discovery in pigs, as new molecular information is accumulating rapidly. Significant progress has been made by identifying candidate gene associations and low-resolution regions containing quantitative trail loci (QTL). However, we are still disadvantaged by the lack of tools available to efficiently use much of this new information. For example, current pig maps are neither of high enough resolution nor sufficiently informative at the comparative level for positional candidate gene cloning within QTL regions. As well, studying biological mechanisms underlying economically important traits such as reproduction is limited by the lack of molecular resources. This is especially important, as reproduction is very difficult to genetically improve by classical breeding methods due to the relatively low heritability and high expense in data collection. Thus, an improved understanding of porcine reproductive biology is of crucial economic importance, yet reproductive processes are poorly characterized at the molecular level. Recently, new methodologies have been brought to bear on a better understanding of pig molecular biology for accelerating genetic improvement in pigs. Several groups are developing molecular information in the pig, and the total Genbank sequence entries for porcine expressed genes have recently topped 100,000. Our Midwest EST Consortium has produced cDNA libraries containing the majority of genes expressed in major female reproductive tissues, and we have deposited nearly 15,000 gene sequences into public databases. These sequences represent over 8,900 different genes, based on sequence comparison among these data. Furthermore, we have developed computer software to automatically extract sequence similarity of these pig genes with their human counterparts, as well as the mapping information of these human homologues. Within our data set, we have identified nearly 1,500 pig genes with strong similarity to mapped human genes, and we are in the process of mapping 700 of these genes to improve the human-pig comparative map. This work and the complementary work of others can now be used to more rapidly understand and identify the genes controlling reproduction, so that genetic improvement of reproduction phenotypes can accelerate

Coagulation status of critically ill patients with and without liver disease assessed using a novel thrombin generation analyzer

Funding Information: NHS Blood and TransplantPeer reviewedPublisher PD

Causality in relativistic many body theory

The stability of the nuclear matter system with respect to density fluctuations is examined exploring in detail the pole structure of the electro-nuclear response functions. Making extensive use of the method of dispersion integrals we calculate the full polarization propagator not only for real energies in the spacelike and timelike regime but also in the whole complex energy plane. The latter proved to be necessary in order to identify unphysical causality violating poles which are the consequence of a neglection of vacuum polarization. On the contrary it is shown that Dirac sea effects stabilize the nuclear matter system shifting the unphysical pole from the upper energy plane back to the real axis. The exchange of strength between these real timelike collective excitations and the spacelike energy regime is shown to lead to a reduction of the quasielastic peak as it is seen in electron scattering experiments. Neglecting vacuum polarization one also obtains a reduction of the quasielastic peak but in this case the strength is partly shifted to the causality violating pole mentioned above which consequently cannot be considered as a physical reliable result. Our investigation of the response function in the energy region above the threshold of nucleon anti-nucleon production leads to another remarkable result. Treating the nucleons as point-like Dirac particles we show that for any isospin independent NN-interaction RPA-correlations provide a reduction of the production amplitude for $p\bar p$-pairs by a factor 2.Comment: 19 pages Latex including 12 postscript figure

Transversality Conditions for Infinite Horizon Variational Problems on Time Scales

We consider problems of the calculus of variations on unbounded time scales. We prove the validity of the Euler-Lagrange equation on time scales for infinite horizon problems, and a new transversality condition.Comment: Submitted 6-October-2009; Accepted 19-March-2010 in revised form; for publication in "Optimization Letters"

The October 1995 ZCAL moving experiment: Output signals and position finding

The response of ZCAL, the E866 Downstream Calorimeter, to changes in gold beam position was examined during the October 1995 running period. Motion in the x direction was achieved by physically moving ZCAL: in the y direction by pitching the beam. These new results for gold incident on a heavily radiation-damaged ZCAL differ substantially from previous data for silicon impinging on a relatively undamaged calorimeter

Very Long Baseline Neutrino Oscillation Experiment for Precise Measurements of Mixing Parameters and CP Violating Effects

We analyze the prospects of a feasible, Brookhaven National Laboratory based, very long baseline (BVLB) neutrino oscillation experiment consisting of a conventional horn produced low energy wide band beam and a detector of 500 kT fiducial mass with modest requirements on event recognition and resolution. Such an experiment is intended primarily to determine CP violating effects in the neutrino sector for 3-generation mixing. We analyze the sensitivity of such an experiment. We conclude that this experiment will allow determination of the CP phase $\delta_{CP}$ and the currently unknown mixing parameter $\theta_{13}$, if $\sin ^2 2 \theta_{13} \geq 0.01$, a value $\sim 15$ times lower than the present experimental upper limit. In addition to $\theta_{13}$ and $\delta_{CP}$, the experiment has great potential for precise measurements of most other parameters in the neutrino mixing matrix including $\Delta m^2_{32}$, $\sin^2 2\theta_{23}$, $\Delta m^2_{21}\times \sin 2 \theta_{12}$, and the mass ordering of neutrinos through the observation of the matter effect in the $\nu_\mu \to \nu_e$ appearance channel.Comment: 12 pages, 10 figure

Perturbation Theory of Neutrino Oscillation with Nonstandard Neutrino Interactions

We discuss various physics aspects of neutrino oscillation with non-standard interactions (NSI). We formulate a perturbative framework by taking \Delta m^2_{21} / \Delta m^2_{31}, s_{13}, and the NSI elements \epsilon_{\alpha \beta} (\alpha, \beta = e, \mu, \tau) as small expansion parameters of the same order \epsilon. Within the \epsilon perturbation theory we obtain the S matrix elements and the neutrino oscillation probability formula to second order (third order in \nu_e related channels) in \epsilon. The formula allows us to estimate size of the contribution of any particular NSI element \epsilon_{\alpha beta} to the oscillation probability in arbitrary channels, and gives a global bird-eye view of the neutrino oscillation phenomena with NSI. Based on the second-order formula we discuss how all the conventional lepton mixing as well as NSI parameters can be determined. Our results shows that while \theta_{13}, \delta, and the NSI elements in \nu_e sector can in principle be determined, complete measurement of the NSI parameters in the \nu_\mu - \nu_\tau sector is not possible by the rate only analysis. The discussion for parameter determination and the analysis based on the matter perturbation theory indicate that the parameter degeneracy prevails with the NSI parameters. In addition, a new solar-atmospheric variable exchange degeneracy is found. Some general properties of neutrino oscillation with and without NSI are also illuminated.Comment: manuscript restructured, discussion of new type of parameter degeneracy added. 47 page