Ira y actividad física. Un estudio en estudiantes universitarios

La actividad física es de vital importancia en estos tiempos donde abunda la incertidumbre y desesperación de las personas. Esta se ha convertido en la solución dado que conociendo sus beneficios y siendo constante se pueden lograr las metas propuestas. Por estas razones, se plantean los siguientes objetivos: analizar el nivel de actividad física e ira y establecer las posibles relaciones entre las variables generales, académicas, psicosociales y físico-deportivas en estudiantes universitarios, con una muestra total de 497 estudiantes universitarios de edades comprendidas entre los 18 y 25 años y una edad media de 21,50 años (DT=6,24). Se han utilizado diversos instrumentos para la consecución de los objetivos como un cuestionario de tipo ad-hoc, para las variables sociodemográficas. Por otra parte, la escala de actitud hacia la actividad física y el cuestionario de agresividad, para las variables psicosociales. Los resultados muestran cómo realizar actividad física de manera diaria y tener una buena actitud hacia esta reduce las conductas agresivas en los estudiantes universitarios y, por ende, ven reducida su irascibilidad

Copernicus Marine Service ocean state report, issue 4

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Anger and physical activity. A study in college students

La actividad física es de vital importancia en estos tiempos donde abunda la incertidumbre y desesperación de las personas. Esta se ha convertido en la solución dado que conociendo sus beneficios y siendo constante se pueden lograr las metas propuestas. Por estas razones, se plantean los siguientes objetivos: analizar el nivel de actividad física e ira y establecer las posibles relaciones entre las variables generales, académicas, psicosociales y físico-deportivas en estudiantes universitarios, con una muestra total de 497 estudiantes universitarios de edades comprendidas entre los 18 y 25 años y una edad media de 21,50 años (DT=6,24). Se han utilizado diversos instrumentos para la consecución de los objetivos como un cuestionario de tipo ad-hoc, para las variables sociodemográficas. Por otra parte, la escala de actitud hacia la actividad física y el cuestionario de agresividad, para las variables psicosociales. Los resultados muestran cómo realizar actividad física de manera diaria y tener una buena actitud hacia esta reduce las conductas agresivas en los estudiantes universitarios y, por ende, ven reducida su irascibilidad.Physical activity is of vital importance in these times where uncertainty and desperation abound. It has become the solution given that knowing its benefits and being constant the proposed goals can be achieved. For these reasons, the following objectives were set: to analyse the level of physical activity and anger and to establish the possible relationships between general, academic, psychosocial and physical-sports variables in university students, with a total sample of 497 university students aged between 18 and 51 years. Various instruments have been used to achieve the objectives such as an ad-hoc questionnaire for the socio-demographic variables.On the other hand, the attitude scale towards physical activity and the Aggressiveness Questionnaire, for the psychosocial variables. The results show how doing physical activity on a daily basis and having a good attitude towards it reduces aggressive behaviour in university students and, thus reduces their irascibility

Enhanced interpretation of newborn screening results without analyte cutoff values

Purpose: To improve quality of newborn screening by tandem mass spectrometry with a novel approach made possible by the collaboration of 154 laboratories in 49 countries. Methods: A database of 767,464 results from 12,721 cases affected with 60 conditions was used to build multivariate pattern recognition software that generates tools integrating multiple clinically significant results into a single score. This score is determined by the overlap between normal and disease ranges, penetration within the disease range, differences between conditions, and weighted correction factors. Results: Ninety tools target either a single condition or the differential diagnosis between multiple conditions. Scores are expressed as the percentile rank among all cases with the same condition and are compared to interpretation guidelines. Retrospective evaluation of past cases suggests that these tools could have avoided at least half of 279 false-positive outcomes caused by carrier status for fatty-acid oxidation disorders and could have prevented 88% of known false-negative events. Conclusion: Application of this computational approach to raw data is independent from single analyte cutoff values. In Minnesota, the tools have been a major contributing factor to the sustained achievement of a false-positive rate below 0.1% and a positive predictive value above 60%. © 2012 American College of Medical Genetics and Genomics

Enhanced interpretation of newborn screening results without analyte cutoff values

Purpose: To improve quality of newborn screening by tandem mass spectrometry with a novel approach made possible by the collaboration of 154 laboratories in 49 countries. Methods: A database of 767,464 results from 12,721 cases affected with 60 conditions was used to build multivariate pattern recognition software that generates tools integrating multiple clinically significant results into a single score. This score is determined by the overlap between normal and disease ranges, penetration within the disease range, differences between conditions, and weighted correction factors. Results: Ninety tools target either a single condition or the differential diagnosis between multiple conditions. Scores are expressed as the percentile rank among all cases with the same condition and are compared to interpretation guidelines. Retrospective evaluation of past cases suggests that these tools could have avoided at least half of 279 false-positive outcomes caused by carrier status for fatty-acid oxidation disorders and could have prevented 88% of known false-negative events. Conclusion: Application of this computational approach to raw data is independent from single analyte cutoff values. In Minnesota, the tools have been a major contributing factor to the sustained achievement of a false-positive rate below 0.1% and a positive predictive value above 60%. © 2012 American College of Medical Genetics and Genomics

Enhanced interpretation of newborn screening results without analyte cutoff values

A collaboration among 157 newborn screening programs in 47 countries has lead to the creation of a database of 705,333 discrete analyte concentrations from 11,462 cases affected with 57 metabolic disorders, and from 631 heterozygotes for 12 conditions. This evidence was first applied to establish disease ranges for amino acids and acylcarnitines, and clinically validate 114 cutoff target ranges. Objective: To improve quality and performance with an evidence-based approach, multivariate pattern recognition software has been developed to aid in the interpretation of complex analyte profiles. The software generates tools that convert multiple clinically significant results into a single numerical score based on overlap between normal and disease ranges, penetration within the disease range, differences between specific conditions, and weighted correction factors. Design: Eighty-five on-line tools target either a single condition or the differential diagnosis between two or more conditions. Scores are expressed as a numerical value and as the percentile rank among all cases with the condition chosen as primary target, and are compared to interpretation guidelines. Tools are updated automatically after any new data submission (2009- 2011: 5.2 new cases added per day on average). Main outcome measures: Retrospective evaluation of past cases suggest that these tools could have avoided at least half of 277 false positive outcomes caused by carrier status for fatty acid oxidation disorders, and could have prevented 88% of false negative events caused by cutoff 7 values set inappropriately. In Minnesota, their prospective application has been a major contributing factor to the sustained achievement of a false positive rate below 0.1% and a positive predictive value above 60%. Conclusions: Application of this computational approach to raw data could make cutoff values for single analytes effectively obsolete. This paradigm is not limited to newborn screening and is applicable to the interpretation of diverse multi-analyte profiles utilized in laboratory medicine. Abstract wor