Doublet bands in 126^{126}Cs in the triaxial rotor model coupled with two quasiparticles

The positive parity doublet bands based on the $\pi h_{11/2}\otimes\nu h_{11/2}$ configuration in $^{126}$Cs have been investigated in the two quasi-particles coupled with a triaxial rotor model. The energy spectra $E(I)$, energy staggering parameter $S(I)=[E(I)-E(I-1)]/2I$, $B(M1)$ and $B(E2)$ values, intraband $B(M1)/B(E2)$ ratios, $B(M1)_{\textrm{in}}/B(M1)_{\textrm{out}}$ ratios, and orientation of the angular momentum for the rotor as well as the valence proton and neutron are calculated. After including the pairing correlation, good agreement has been obtained between the calculated results and the data available, which supports the interpretation of this positive parity doublet bands as chiral bands.Comment: Phys.Rev.C (accepted

Differential in vitro infection of neural cells by astroviruses

Encephalitis remains a diagnostic conundrum in humans as over 50% of cases are managed without the identification of an etiology. Astroviruses have been detected from the central nervous system of mammals in association with disease, suggesting that this family of RNA viruses could be responsible for cases of some neurological diseases that are currently without an ascribed etiology. However, there are significant barriers to understanding astrovirus infection as the capacity of these viruses to replicate in nervous system cells in vitro has not been determined. We describe primary and immortalized cultured cells of the nervous system that support infection by astroviruses. These results further corroborate the role of astroviruses in causing neurological diseases and will serve as an essential model to interrogate the neuropathogenesis of astrovirus infection.Recent advances in unbiased pathogen discovery have implicated astroviruses as pathogens of the central nervous system (CNS) of mammals, including humans. However, the capacity of astroviruses to be cultured in CNS-derived cells in vitro has not been reported to date. Both astrovirus VA1/HMO-C (VA1; mamastrovirus 9) and classic human astrovirus 4 (HAstV4; mamastrovirus 1) have been previously detected from cases of human encephalitis. We tested the ability of primary human neurons, primary human astrocytes, and other immortalized human nervous system cell lines (SK-N-SH, U87 MG, and SW-1088) to support infection and replication of these two astrovirus genotypes. Primary astrocytes and SK-N-SH cells supported the full viral life cycle of VA1 with a >100-fold increase in viral RNA levels during a multistep growth curve, detection of viral capsid, and a >100-fold increase in viral titer. Primary astrocytes were permissive with respect to HAstV4 infection and replication but did not yield infectious virus, suggesting abortive infection. Similarly, abortive infection of VA1 was observed in SW-1088 and U87 MG cells. Elevated expression of the chemokine CXCL10 was detected in VA1-infected primary astrocytes and SK-N-SH cells, suggesting that VA1 infection can induce a proinflammatory host response. These findings establish an in vitro cell culture model that is essential for investigation of the basic biology of astroviruses and their neuropathogenic potential

Mobility Increases the Data Offloading Ratio in D2D Caching Networks

Caching at mobile devices, accompanied by device-to-device (D2D) communications, is one promising technique to accommodate the exponentially increasing mobile data traffic. While most previous works ignored user mobility, there are some recent works taking it into account. However, the duration of user contact times has been ignored, making it difficult to explicitly characterize the effect of mobility. In this paper, we adopt the alternating renewal process to model the duration of both the contact and inter-contact times, and investigate how the caching performance is affected by mobility. The data offloading ratio, i.e., the proportion of requested data that can be delivered via D2D links, is taken as the performance metric. We first approximate the distribution of the communication time for a given user by beta distribution through moment matching. With this approximation, an accurate expression of the data offloading ratio is derived. For the homogeneous case where the average contact and inter-contact times of different user pairs are identical, we prove that the data offloading ratio increases with the user moving speed, assuming that the transmission rate remains the same. Simulation results are provided to show the accuracy of the approximate result, and also validate the effect of user mobility.Comment: 6 pages, 5 figures, accepted to IEEE Int. Conf. Commun. (ICC), Paris, France, May 201