61 research outputs found
An Analysis of Heroku and AWS for Growing Startups
This project presents information on the architecture of most modern cloud-hosting platforms, and gives a cost-benefit analysis of two common Platform-as-a-Service (PaaS) companies: Heroku and AWS
Behavior of a polymer chain in a critical binary solvent
We present a field-theoretic renormalization group analysis of a polymer
chain immersed in a binary good solvent close to its critical demixing point.
We first show that this problem can be mapped on a bicritical field theory,
i.e. a -model with a mass anisotropy. This implies that the
end-to-end distance of the polymer is now controlled by a new critical exponent
related to the quadratic mass anisotropy operator . To show this
we solve the RG equation and calculate explicitly the exponents and the mean
end-to-end length of the chain.Comment: 6 pages, accepted in Europhys. Let
The scaling behaviour of screened polyelectrolytes
We present a field-theoretic renormalization group (RG) analysis of a single
flexible, screened polyelectrolyte chain (a Debye-H\"uckel chain) in a polar
solvent. We point out that the Debye-H\"uckel chain may be mapped onto a local
field theory which has the same fixed point as a generalised Potts
model. Systematic analysis of the field theory shows that the system is one
with two interplaying length-scales requiring the calculation of scaling
functions as well as exponents to fully describe its physical behaviour. To
illustrate this, we solve the RG equation and explicitly calculate the
exponents and the mean end-to-end length of the chain.Comment: 6 pages, 1 figure; changed title and slight modification to tex
Computer-aided detection (CAD) for breast MRI: evaluation of efficacy at 3.0 T
OBJECTIVE: The purpose of the study was to evaluate the accuracy of 3.0-T breast MRI interpretation using manual and fully automated kinetic analyses. MATERIAL AND METHODS: Manual MRI interpretation was done on an Advantage Workstation. Retrospectively, all examinations were processed with a computer-aided detection (CAD) system. CAD data sets were interpreted by two experienced breast radiologists and two residents. For each lesion automated analysis of enhancement kinetics was evaluated at 50% and 100% thresholds. Forty-nine malignant and 22 benign lesions were evaluated. RESULTS: Using threshold enhancement alone, the sensitivity and specificity of CAD were 97.9% and 86.4%, respectively, for the 50% threshold, and 97.9% and 90%, respectively, for the 100% threshold. Manual interpretation by two breast radiologists showed a sensitivity of 84.6% and a specificity of 68.8%. For the same two radiologists the mean sensitivity and specificity for CAD-based interpretation was 90.4% (not significant) and 81.3% (significant at p < 0.05), respectively. With one-way ANOVA no significant differences were found between the two breast radiologists and the two residents together, or between any two readers separately. CONCLUSION: CAD-based analysis improved the specificity compared with manual analysis of enhancement. Automated analysis at 50% and 100% thresholds showed a high sensitivity and specificity for readers with varying levels of experience
The Hydration Structure at Yttria-Stabilized Cubic Zirconia (110)-Water Interface with Sub-Angstrom Resolution
The interfacial hydration structure of yttria-stabilized cubic zirconia (110) surface in contact with water was determined with ~0.5&#8201;&Aring; resolution by high-resolution X-ray reflectivity measurement. The terminal layer shows a reduced electron density compared to the following substrate lattice layers, which indicates there are additional defects generated by metal depletion as well as intrinsic oxygen vacancies, both of which are apparently filled by water species. Above this top surface layer, two additional adsorbed layers are observed forming a characteristic interfacial hydration structure. The first adsorbed layer shows abnormally high density as pure water and likely includes metal species, whereas the second layer consists of pure water. The observed interfacial hydration structure seems responsible for local equilibration of the defective surface in water and eventually regulating the long-term degradation processes. The multitude of water interactions with the zirconia surface results in the complex but highly ordered interfacial structure constituting the reaction front.ope
Free energy and molecular dynamics calculations for the cubic-tetragonal phase transition in zirconia
The high-temperature cubic-tetragonal phase transition of pure stoichiometric
zirconia is studied by molecular dynamics (MD) simulations and within the
framework of the Landau theory of phase transformations. The interatomic forces
are calculated using an empirical, self-consistent, orthogonal tight-binding
(SC-TB) model, which includes atomic polarizabilities up to the quadrupolar
level. A first set of standard MD calculations shows that, on increasing
temperature, one particular vibrational frequency softens. The temperature
evolution of the free energy surfaces around the phase transition is then
studied with a second set of calculations. These combine the thermodynamic
integration technique with constrained MD simulations. The results seem to
support the thesis of a second-order phase transition but with unusual, very
anharmonic behaviour above the transition temperature
Relative energetics and structural properties of zirconia using a self-consistent tight-binding model
We describe an empirical, self-consistent, orthogonal tight-binding model for
zirconia, which allows for the polarizability of the anions at dipole and
quadrupole levels and for crystal field splitting of the cation d orbitals.
This is achieved by mixing the orbitals of different symmetry on a site with
coupling coefficients driven by the Coulomb potentials up to octapole level.
The additional forces on atoms due to the self-consistency and polarizabilities
are exactly obtained by straightforward electrostatics, by analogy with the
Hellmann-Feynman theorem as applied in first-principles calculations. The model
correctly orders the zero temperature energies of all zirconia polymorphs. The
Zr-O matrix elements of the Hamiltonian, which measure covalency, make a
greater contribution than the polarizability to the energy differences between
phases. Results for elastic constants of the cubic and tetragonal phases and
phonon frequencies of the cubic phase are also presented and compared with some
experimental data and first-principles calculations. We suggest that the model
will be useful for studying finite temperature effects by means of molecular
dynamics.Comment: to be published in Physical Review B (1 march 2000
Ultrasound-Guided Laser-Induced Thermal Therapy for Small Palpable Invasive Breast Carcinomas: A Feasibility Study
First-principles characterization of a heteroceramic interface: ZrO2(001) deposited on an alpha-Al2O3(1(1)over-bar02) substrate
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