Of Candidates and Character

We study the characteristics of self-selected candidates in corrupt political systems. Potential candidates differ along two dimensions of unobservable character: public spirit (altruism toward others) and honesty (the disutility suffered when selling out to special interests after securing office). Both aspects combine to determine an individual's quality as governor. We characterize properties of equilibrium candidate pools for arbitrary costs of running for office. As the cost of running vanishes, there is an essentially unique candidate pool, which is typically highly asymmetric: it consists of only the most dishonest individuals but a mixture of the most selfish and the most public-spirited ones. We explore how two policy instruments -- the governor's compensation and anti-corruption enforcement -- affect the expected quality of governance through candidate self-selection. We also examine the effects of incumbency and term limits on self-selection in a dynamic version of the model.

New cluster members and halo stars of the Galactic globular cluster NGC 1851

NGC 1851 is an intriguing Galactic globular cluster, with multiple stellar evolutionary sequences, light and heavy element abundance variations and indications of a surrounding stellar halo. We present the first results of a spectroscopic study of red giant stars within and outside of the tidal radius of this cluster. Our results identify nine probable new cluster members (inside the tidal radius) with heliocentric radial velocities consistent with that of NGC 1851. We also identify, based on their radial velocities, four probable extratidal cluster halo stars at distances up to ~3.1 times the tidal radius, which are supportive of previous findings that NGC 1851 is surrounded by an extended stellar halo. Proper motions were available for 12 of these 13 stars and all are consistent with that of NGC 1851. Apart from the cluster members and cluster halo stars, our observed radial velocity distribution agrees with the expected distribution from a Besancon disk/N-body stellar halo Milky Way model generated by the Galaxia code, suggesting that no other structures at different radial velocities are present in our field. The metallicities of these stars are estimated using equivalent width measurements of the near infrared calcium triplet absorption lines and are found, within the limitations of this method, to be consistent with that of NGC 1851. In addition we recover 110 red giant cluster members from previous studies based on their radial velocities and identify three stars with unusually high radial velocities.Comment: 10 pages, 8 figures. Accepted for publication in MNRA

New halo stars of the Galactic globular clusters M3 and M13 in the LAMOST DR1 Catalog

M3 and M13 are Galactic globular clusters with previous reports of surrounding stellar halos. We present the results of a search for members and extratidal cluster halo stars within and outside of the tidal radius of these clusters in the LAMOST Data Release 1. We find seven candidate cluster members (inside the tidal radius) of both M3 and M13 respectively. In M3 we also identify eight candidate extratidal cluster halo stars at distances up to ~9.8 times the tidal radius, and in M13 we identify 12 candidate extratidal cluster halo stars at distances up to ~13.8 times the tidal radius. These results support previous indications that both M3 and M13 are surrounded by extended stellar halos, and we find that the GC destruction rates corresponding to the observed mass loss are generally significantly higher than theoretical studies predict.Comment: 21 pages, 10 figures. Accepted for publication in Ap

A comparative study on the effectiveness of bupivacaine and ropivacaine for supraclavicular block

Background: Bupivacaine and Ropivacaine have been extensively studied &their properties with respect to onset, duration and quality of block. This study aims to detect whether addition of clonidine to both of them changes their properties. This study also aims to use lower than usual dosages for both the local anesthetics to prevent adverse effects of local anesthetics.Methods: After obtaining ethical approval, the study was carried out on patients undergoing elective upper limb surgeries. They were randomly divided into two Groups: Group B and Group R. The onset and duration of sensory and motor blockade and other parameters were assessed.Results: The onset of blockade, both sensory & motor was earlier in Ropivacaine as compared to Bupivacaine group. Mean duration of blockade, both sensory & motor, was more in the Bupivacaine group.  Conclusions: Addition of Clonidine enabled the use of low concentrations (0.25%) of both the anesthetics. Also, Ropivacaine (0.25%) has faster onset of sensory and motor blockade, shorter duration of action and less motor blockade compared to Bupivacaine

ESO452-SC11: The lowest mass globular cluster with a potential chemical inhomogeneity

We present the largest spectroscopic investigation of one of the faintest and least studied stellar clusters of the Milky Way, ESO452-SC11. Using the Anglo-Australian Telescope AAOmega and Keck HIRES spectrographs we have identified 11 members of the cluster and found indications of star-to-star light element abundance variation, primarily using the blue cyanogen (CN) absorption features. From a stellar density profile, we estimate a total cluster mass of $(6.8\pm3.4)\times10^3$ solar masses. This would make ESO452-SC11 the lowest mass cluster with evidence for multiple populations. These data were also used to measure the radial velocity of the cluster ($16.7\pm0.3$ km s$^{-1}$) and confirm that ESO452-SC11 is relatively metal-rich for a globular cluster ([Fe/H]$=-0.81\pm0.13$). All known massive clusters studied in detail show multiple populations of stars each with a different chemical composition, but many low-mass globular clusters appear to be chemically homogeneous. ESO452-SC11 sets a lower mass limit for the multiple stellar population phenomenon.Comment: 13 pages, 11 figures. Accepted for publication in MNRA

New 4-Thiazolidinones of Nicotinic Acid with 2-Amino-6-methylbenzothiazole and their Biological Activity

The title compounds 6a–j, 2-[(6-methyl-1,3-benzothiazol-2-yl)amino]-N-[2-(substituted phenyl/furan-2-yl)-4-oxo-1,3-thiazolidin-3-yl]nicotinamides, were prepared from 2-chloropyridine-3-carboxylic acid (1) and 2-amino-6-methyl-benzothiazole (2) by known methods. All the compounds have been established by IR, 1H NMR, 13C NMR and elemental analyses. The in vitro antimicrobial screening of the compounds were carried out against two Gram positive (S. aureus, S. pyogenes), two Gram negative (E. coli, P. aeruginosa) bacteria and three fungal species (C. albicans, A. niger, A. clavatus) using the broth microdilution method. Some of the compounds are comparable with standard drugs

Synthesis and Antimicrobial Activity of 3-(1,3,4-Oxadiazol-2-yl)quinazolin-4(3H)-ones

In attempt to find new pharmacologically active molecules, we report here the synthesis and in vitro antimicrobial activity of various 3-(1,3,4-oxadiazol-2-yl)-quinazolin-4(3H)-ones. The antimicrobial activity of title compounds were examined against two gram positive bacteria (S. aureus, S. pyogenes), two gram negative bacteria (E. coli, P. aeruginosa) and three fungi (C. albicans, A. niger, A. clavatus) using the broth microdilution method. Some derivatives bearing a bromo or iodo group exhibited very good antimicrobial activity

ISONIAZID THE CULPRIT BEHIND TOXIC OPTIC NEUROPATHY

 Literature regarding toxic optic neuropathy (TON) due to isoniazid (INH) is scarce. This diagnosis is often missed, leading to unnecessary delay in institution of corrective measures. Often, this delay can worsen the patient's vision, with a high likelihood of development of serious damage to the patient's vision. We report a case of a 49-year-old gentleman, afflicted with meningeal tuberculosis, who developed visual disturbances following the administration of antitubercular therapy. The patient's vision improved dramatically following INH's withdrawal. This case highlighted the need to keep INH as a possible cause for TON, especially if vision does not improve following ethambutol's withdrawal. Further, this case attests to the need for thorough and periodic visual examinations in patients receiving antitubercular therapy.Â