Status of child well-being among rural families in Manmunai South West DS division of Batticaloa District: impact of an agricultural livelihood project

Sustainable livelihood development projects are a vital modern method in fighting against poverty and reducing unemployment. An agricultural livelihood project had been implemented by the World Vision Lanka, a non-governmental organization in Manmunai South West Divisional Secretariat Division of Batticaloa District during the period 2010 – 2015. The project was channeled through four activities; family development, goat rearing, cattle rearing and poultry development in all Grama Niladhari divisions. The present study was implemented with the objective to identify the extent to which the implemented agricultural livelihood project changes the child well-being status among the people. Questionnaires were administered to 100 randomly selected project beneficiaries through personal interview in five GN Divisions. Collected data were analyzed by using SPSS. The results reveal that majority of the beneficiaries have succeeded in their income generating activities. Significant satisfaction reported for goat and cattle rearing. Child well-being indicators changed positively in comparison with the status before the implementation of the project. Further, beneficiaries are satisfied about the wellbeing of their children. The said income generating activities need to be intensified to sustain the present status. Therefore, relevant authorities should take needed actions to intensify the income generating activities of the rural populace in the area

Investigation into Cardiac Myhc-α 334-352-Specific TCR Transgenic Mice Reveals a Role for Cytotoxic CD4 T Cells in the Development of Cardiac Autoimmunity

Myocarditis is one of the major causes of heart failure in children and young adults and can lead to dilated cardiomyopathy. Lymphocytic myocarditis could result from autoreactive CD4+ and CD8+ T cells, but defining antigen specificity in disease pathogenesis is challenging. To address this issue, we generated T cell receptor (TCR) transgenic (Tg) C57BL/6J mice specific to cardiac myosin heavy chain (Myhc)-α 334-352 and found that Myhc-α-specific TCRs were expressed in both CD4+ and CD8+ T cells. To investigate if the phenotype is more pronounced in a myocarditis-susceptible genetic background, we backcrossed with A/J mice. At the fourth generation of backcrossing, we observed that Tg T cells from naïve mice responded to Myhc-α 334-352, as evaluated by proliferation assay and carboxyfluorescein succinimidyl ester staining. The T cell responses included significant production of mainly pro-inflammatory cytokines, namely interferon (IFN)-γ, interleukin-17, and granulocyte macrophage-colony stimulating factor. While the naïve Tg mice had isolated myocardial lesions, immunization with Myhc-α 334-352 led to mild myocarditis, suggesting that further backcrossing to increase the percentage of A/J genome close to 99.99% might show a more severe disease phenotype. Further investigations led us to note that CD4+ T cells displayed the phenotype of cytotoxic T cells (CTLs) akin to those of conventional CD8+ CTLs, as determined by the expression of CD107a, IFN-γ, granzyme B natural killer cell receptor (NKG)2A, NKG2D, cytotoxic and regulatory T cell molecules, and eomesodermin. Taken together, the transgenic system described in this report may be a helpful tool to distinguish the roles of cytotoxic cardiac antigen-specific CD4+ T cells vs. those of CD8+ T cells in the pathogenesis of myocarditis

Modulatory and regenerative potential of transplanted bone marrow derived mesenchymal stem cells on rifampicin-induced kidney toxicity

Anti-tuberculosis agent rifampicin is extensively used for its effectiveness. Possible complications of tuberculosis and prolonged rifampicin treatment include kidney damage; these conditions can lead to reduced efficiency of the affected kidney and consequently to other diseases. Bone marrow-derived mesenchymal stem cells (BMMSCs) can be used in conjunction with rifampicin to avert kidney damage; because of its regenerative and differentiating potentials into kidney cells. This research was designed to assess the modulatory and regenerative potentials of MSCs in averting kidney damage due to rifampicin-induced kidney toxicity in Wistar rats and their progenies. BMMSCs used in this research were characterized according to the guidelines of International Society for Cellular Therapy

Optimal Placement Identification of Multiple DG Types Using Optimization Technique

In this paper, a combination algorithm called GAIPSO, which combines GA and a better version of the classic particle swarm optimization process, is used. In order to calculate the data enhancement in voltage profile, this study uses the GWO algorithm. The ideal position for the proposed charging points inside the distribution system is the goal. The received comment thread solution (site & station size) is further re-optimized by PSO, improving both the functionality and outcome overall. Studies based on simulations show that the above mentioned technique outperforms GA, GWO, and PSO in respect of an improved voltage profiles as well as the quality of the solution found for the objective function. Optimum planning for the charging station’s location and size. the IEEE 33 bus system. The suggested approach takes into consideration the IEEE 33 bus service. The received thread solutions (site and station size) is further re-optimized by PSO, improving both the performance and outcome overall

Reduced Graphene Oxide Embedded V2O5 Nanorods and Porous Honey Carbon as High Performance Electrodes for Hybrid Sodium-ion Supercapacitors

Attaining high energy density and power density in a single energy storage device is still a major challenge for electrochemical energy storage research community. Sodium-ion hybrid supercapacitor is a sustainable energy storage system which accomplishes the gap between battery and supercapacitor comprises of high energy density-battery type faradaic anode and high power density-supercapacitor type non-faradaic cathode. Here we have reported high surface area (1554 m2 g�1 ) activated porous carbon obtained from naturally occurring viscous liquid honey as a cathode and sol-gel derived, V2O5 nanorods anchored reduced graphene oxide (rGO) nanocomposite as an anode for non- aqueous sodiumion capacitor. When explored honey derived carbon as a non-faradaic cathode, it exhibits a higher specific capacitance of 224 F g�1 and V2O5@rGO anode delivers the maximum capacitance of 289 F g�1 at 0.01 A g�1 vs Na/Na+ . The prepared V2O5@rGO anode has long stable cycle life (V2O5 nanorods@rGO retains 85% of the initial capacitance (112.2 F g�1 ) at the current density of 0.06 A g�1 after 1000 cycles). The assembled sodium-ion capacitor (NIC) using honey derived activated carbon (AC) and V2O5@rGO anode delivers the energy density of 65Wh kg�1 and power density of 72W kg�1 at 0.03 A g�1. The capacity retention is 74% after 1000 cycles at the current density of 0.06 Ag�1. The assembled sodium-ion hybrid capacitor delivers maximum energy and power density and exhibits very long stable cycle lif

Implementation of RFID to protect the neonate in hospitals from abduction

While utmost fitness administrators agree that a regulation Pink, the regulation phrase to gesture a toddler capture is an oddity in scientific institutions, it is nonetheless a bother that ought to be taken significantly through a sanitarium. Not solely can it devastate the household concerned and scarify the staff, however it can additionally signify disastrous long- continuing penalties for the sanitarium’s photograph and character. Precluding a regulation Pink is, thus, a pinnacle priority that requires preceding planning, cautious format of bodily walls, and the perpetration of the proper applied sciences in order to supply peace of thinking to households and caregivers when it comes to guarding sprog instances from the opportunity of a foreigner or certainly a household seize. Radio Frequency Identification or RFID is an computerized identification technological know-how that helps the soreness script. RFID workshop with the aid of having a analyzing machine checkup a small digital label the usage of radio frequency signals

A Siddha Management of Chronic Tonsillitis - A Case Report

Aim and objective: In the present scenario the medicine system from the west has started acknowledging the importance and wisdom of the ancient medicine system such as Siddha, Ayurvedha, Unani. There are many diseases that need surgical procedures till date, so in order to find a probable cure now a paradigm shift is really important. Tonsillitis is an infection of the tonsils associated with a sore throat, difficulty in swallowing, fever, etc. Still, surgical removal of tonsils is one of the most frequent procedures during childhood. In the Siddha system of medicine tonsillitis can be compared with Virana silatham. To evaluate the effect of Siddha medicine in the management of tonsillitis. Materials and Methods: The subject approached Out Patient Department of Siddha Clinical Research Unit(SCRU),under Central Council for Research in Siddha(CCRS), Safdarjung Hospital Campus, New Delhi with symptoms of sore throat, ear pain, difficulty in swallowing, sleep apnoea, which involved problems of breathing at night and foul smell from the mouth for past four months systemically. Discussion: The manifestation of symptoms and their severity depends on the extent of involvement of Uyir thathukkal (Vali,Azhal, Iyyam). Though the disease is Iyyam and Azhal predominant, there is derangement of Iyyam and Azhal Dosham in Virana silatham. Results: In this case, the subject showed a marked improvement as depicted in the photographs taken at different levels of treatment, also there was a significant improvement noted in both subjective and objective parameters. By adopting the Siddha treatment approach with an external treatment modality an attempt is made to bring about satisfactory results

Forecasting Ionospheric TEC Changes Associated with the December 2019 and June 2020 Solar Eclipses: A Comparative Analysis of OKSM, FFNN, and DeepAR Models

This paper presents forecast and investigation of the variation in ionospheric Total Electron Content (TEC) during the solar eclipses (SEs) of December 2019 and June 2020 using three different methods: Deep Autoregressive model (DeepAR), Feed-Forward Neural Network (FFNN), and Ordinary Kriging-based Surrogate Model (OKSM), and the TEC data predicted by DeepAR, FFNN, and OKSM were compared with the actual TEC during the observation days. The study was conducted based on GPS data taken from the IISC receiver located in Bangalore, India, during the SEs which happened on 26.12.2019 and 21.06.2020. The TEC data were examined to assess the effect of solar eclipses on TEC values. Eighty-day prior TEC data for the IISC station are gathered from IONOLAB servers along with the other parameter data like Dst, Ap, F10.7, and Kp taken from OMNIWEB servers which were used to predict TEC. The reliability of the forecasted results is evaluated using numerical factors like Normalized Root Mean Square Error (NRMSE), Correlation Coefficient (CC), Root Mean Square Error (RMSE), Mean Absolute Error (MAE), and R-squared. The study demonstrates the usefulness of combining multiple methods for analyzing TEC variations during SEs and highlights the potential of OKSM, FFNN, and DeepAR models for studying TEC variation in the same context. The findings may be useful for satellite broadcasting and navigational services and for further research into the influence of solar eclipses on the TEC changes