A revision of the Sphaeriidae of North America (Mollusca: Pelecypoda)

http://deepblue.lib.umich.edu/bitstream/2027.42/56362/1/MP118.pd

Beyond Legislative Schizophrenia: Sustaining Long-Term Educational Reform and Short-Term Viability

A major challenge facing contemporary educational reform is the extended timeframe necessary to achieve substantive and demonstrable results

Light-activated modulation and coupling in integrated polymer-liquid crystal systems

We explore the transfer of an incident light pattern onto the liquid crystal (LC) bulk in a photorefractive cell through an integrated photoconducting layer that modulates the electric field applied to the device. The electrical properties and the strength of modulation are investigated as a function of the incident light intensity as well as the frequency and amplitude of the applied voltage, for two LCs with very different electrical conductivity. A simplified electrical model of the cell is proposed, demonstrating that the LC conductivity is a key factor determining the beam-coupling strength

A Heuristic Evolutionary Method for the Complementary Cell Suppression Problem

Cell suppression is a common method for disclosure avoidance used to protect sensitive information in two-dimensional tables where row and column totals are published along with non-sensitive data. In tables with only positive cell values, cell suppression has been demonstrated to be non-deterministic NP-hard. Therefore, finding more efficient methods for producing low-cost solutions is an area of active research. Genetic algorithms (GA) have shown to be effective in finding good solutions to the cell suppression problem. However, these methods have the shortcoming that they tend to produce a large proportion of infeasible solutions. The primary goal of this research was to develop a GA that produced low-cost solutions with fewer infeasible solutions created at each generation than previous methods without introducing excessive CPU runtime costs. This research involved developing a GA that produces low-cost solutions with fewer infeasible solutions produced at each generation; and implementing selection and replacement operations that maintained genetic diversity during the evolution process. The GA\u27s performance was tested using tables containing 10,000 and 100,000 cells. The primary criterion for the evaluation of effectiveness of the GA was total cost of the complementary suppressions and the CPU runtime. Experimental results indicate that the GA-based method developed in this dissertation produced better quality solutions than those produced by extant heuristics. Because existing heuristics are very effective, this GA-based method was able to surpass them only modestly. Existing evolutionary methods have also been used to improve upon the quality of solutions produced by heuristics. Experimental results show that the GA-based method developed in this dissertation is computationally more efficient than GA-based methods proposed in the literature. This is attributed to the fact that the specialized genetic operators designed in this study produce fewer infeasible solutions. The results of these experiments suggest the need for continued research into non-probabilistic methods to seed the initial populations, selection and replacement strategies that factor in genetic diversity on the level of the circuits protecting sensitive cells; solution-preserving crossover and mutation operators; and the use of cost benefit ratios to determine program termination

The perceived barriers to the inclusion of rainwater harvesting systems by UK house building companies

This work investigates the barriers that exist to deter the implementation of rainwater harvesting into new UK housing. A postal questionnaire was sent to a selection of large, medium and small house-builders distributed across the UK. Questions were asked concerning potential barriers to the inclusion of rainwater harvesting in homes separated into five sections; (1) institutional and regulatory gaps, (2) economic and financial constraints, (3) absence of incentives, (4) lack of information and technical knowledge, and (5) house-builder attitudes. The study concludes that although the knowledge of rainwater systems has increased these barriers are deterring house-builders from installing rainwater harvesting systems in new homes. It is further acknowledged that the implementation of rainwater harvesting will continue to be limited whilst these barriers remain and unless resolved, rainwater harvesting's potential to reduce the consumption of potable water in houses will continue to be limited

External Workloads Vary by Position and Game Result in US-based Professional Soccer Players

International Journal of Exercise Science 16(6): 688-699, 2023. Professional soccer is a physically demanding sport that requires players to be highly trained. Advances using GPS allow the tracking of external workloads for individual players in practice and competition, however, there is a lack of evidence on how these measures impact match results. Therefore, we analyzed external workloads by player position and determined if they vary depending on the result of competitive matches. External workloads were analyzed in professional soccer players (n = 25) across 28 competitive games. One-way ANOVA determined if workloads varied by position (striker – ST, wide midfielder - WM, central midfielder – CM, wide defender - WD, central defender – CD) or across games won (n = 8), lost (n = 13) or tied (n = 7). Repeated-measures ANOVA assessed differences in workloads specific to each position in each of the result categories. Statistical significance was set at p \u3c 0.05. Across all games, more high-speed and very-high speed running was done by ST and WD compared to CD (p \u3c 0.001) and CM (p \u3c 0.001 - 0.02). Whole-team data showed no differences in any external workload variable with respect to match result (p \u3e 0.05), however, in games won ST did more very high-speed running than in losing games (p = 0.03) and defending players did more high and very high-speed running in games tied vs. those won or lost (p \u3c 0.05). Whole-team external workloads do not vary depending on the match result; however, high speed running may be a differentiating factor at the positional level. Coaches should consider position-specific analysis when examining player workloads

Efficacy of Online Training for Improving Camp Staff Competency

Preparing competent staff is a critical issue within the camp community. This quasi-experimental study examined the effectiveness of an online course for improving staff competency in camp healthcare practices among college-aged camp staff and a comparison group (N = 55). We hypothesized that working in camp would increase competency test scores due to opportunities for staff to experientially apply knowledge learned online. Hierarchical linear modeling was used to analyse the cross-level effects of a between-individuals factor (assignment to experimental or comparison group) and within-individual effects of time (pre-test, post-test #1, and post-test #2) on online course test scores. At post-test #2, the difference in average test scores between groups was ~30 points, with the treatment group scoring lower on average than the comparison group. Factors that may have influenced these findings are explored, including fatigue and the limited durability of online learning. Recommendations for research and practice are discussed

Metabolic Syndrome Derived from Principal Component Analysis and Incident Cardiovascular Events: The Multi Ethnic Study of Atherosclerosis (MESA) and Health, Aging, and Body Composition (Health ABC).

Background. The NCEP metabolic syndrome (MetS) is a combination of dichotomized interrelated risk factors from predominantly Caucasian populations. We propose a continuous MetS score based on principal component analysis (PCA) of the same risk factors in a multiethnic cohort and compare prediction of incident CVD events with NCEP MetS definition. Additionally, we replicated these analyses in the Health, Aging, and Body composition (Health ABC) study cohort. Methods and Results. We performed PCA of the MetS elements (waist circumference, HDL, TG, fasting blood glucose, SBP, and DBP) in 2610 Caucasian Americans, 801 Chinese Americans, 1875 African Americans, and 1494 Hispanic Americans in the multiethnic study of atherosclerosis (MESA) cohort. We selected the first principal component as a continuous MetS score (MetS-PC). Cox proportional hazards models were used to examine the association between MetS-PC and 5.5 years of CVD events (n = 377) adjusting for age, gender, race, smoking and LDL-C, overall and by ethnicity. To facilitate comparison of MetS-PC with the binary NCEP definition, a MetS-PC cut point was chosen to yield the same 37% prevalence of MetS as the NCEP definition (37%) in the MESA cohort. Hazard ratio (HR) for CVD events were estimated using the NCEP and Mets-PC-derived binary definitions. In Cox proportional models, the HR (95% CI) for CVD events for 1-SD (standard deviation) of MetS-PC was 1.71 (1.54-1.90) (P < 0.0001) overall after adjusting for potential confounders, and for each ethnicity, HRs were: Caucasian, 1.64 (1.39-1.94), Chinese, 1.39 (1.06-1.83), African, 1.67 (1.37-2.02), and Hispanic, 2.10 (1.66-2.65). Finally, when binary definitions were compared, HR for CVD events was 2.34 (1.91-2.87) for MetS-PC versus 1.79 (1.46-2.20) for NCEP MetS. In the Health ABC cohort, in a fully adjusted model, MetS-PC per 1-SD (Health ABC) remained associated with CVD events (HR = 1.21, 95%CI 1.12-1.32) overall, and for each ethnicity, Caucasian (HR = 1.24, 95%CI 1.12-1.39) and African Americans (HR = 1.16, 95%CI 1.01-1.32). Finally, when using a binary definition of MetS-PC (cut point 0.505) designed to match the NCEP definition in terms of prevalence in the Health ABC cohort (35%), the fully adjusted HR for CVD events was 1.39, 95%CI 1.17-1.64 compared with 1.46, 95%CI 1.23-1.72 using the NCEP definition. Conclusion. MetS-PC is a continuous measure of metabolic syndrome and was a better predictor of CVD events overall and in individual ethnicities. Additionally, a binary MetS-PC definition was better than the NCEP MetS definition in predicting incident CVD events in the MESA cohort, but this superiority was not evident in the Health ABC cohort

Widefield light sheet microscopy using an Airy beam combined with deep-learning super-resolution

Imaging across length scales and in depth has been an important pursuit of widefield optical imaging. This promises to reveal fine cellular detail within a widefield snapshot of a tissue sample. Current advances often sacrifice resolution through selective sub-sampling to provide a wide field of view in a reasonable time scale. We demonstrate a new avenue for recovering high-resolution images from sub-sampled data in light sheet microscopy using deep-learning super-resolution. We combine this with the use of a widefield Airy beam to achieve high-resolution imaging over extended fields of view and depths. We characterise our method on fluorescent beads as test targets. We then demonstrate improvements in imaging amyloid plaques in a cleared brain from a mouse model of Alzheimer’s disease, and in excised healthy and cancerous colon and breast tissues. This development can be widely applied in all forms of light sheet microscopy to provide a two-fold increase in the dynamic range of the imaged length scale. It has the potential to provide further insight into neuroscience, developmental biology, and histopathology