Bures geometry of the three-level quantum systems. II

For the eight-dimensional Riemannian manifold comprised by the three-level quantum systems endowed with the Bures metric, we numerically approximate the integrals over the manifold of several functions of the curvature and of its (anti-)self-dual parts. The motivation for pursuing this research is to elaborate upon the findings of Dittmann in his paper, "Yang-Mills equation and Bures metric" (quant-ph/9806018).Comment: thirteen pages, LaTeX, four tables, two figures, this paper supersedes math-ph/0012031, "Numerical analyses of a quantum-theoretic eight-dimensional Yang-Mills fields," which will be withdrawn. For part I of this paper (to appear in J. Geom. Phys.), see quant-ph/000806

Clozapine as add-on medication in the maintenance treatment of bipolar and schizoaffective disorders - A case series

Atypical neuroleptics are increasingly used in the treatment of bipolar and schizoaffective disorders. Currently, numerous controlled short-term studies are available for clozapine, olanzapine, risperidone or quetiapine, but long-term data are still missing. Three patients (2 with bipolar disorder, 1 with schizoaffective disorder) are described who showed a marked reduction of affective symptomatology after clozapine had been added to mood stabilizer pretreatment. The patients were seen once a month before and after the introduction of clozapine for at least 6 months. Treatment response was evaluated using different rating scales (IDS, YMRS; GAF; CGIBP) and the NIMH Life Chart Methodology. All patients showed a marked improvement after the add-on treatment with clozapine had been initiated. Clozapine was tolerated well with only transient and moderate weight gain and fatigue as only side effects. This case series underlines the safety and efficacy of clozapine as add-on medication in the treatment of bipolar and schizoaffective disorders. Copyright (C) 2002 S. Karger AG, Basel

Effective sigma models and lattice Ward identities

We perform a lattice analysis of the Faddeev-Niemi effective action conjectured to describe the low-energy sector of SU(2) Yang-Mills theory. To this end we generate an ensemble of unit vector fields ("color spins") n from the Wilson action. The ensemble does not show long-range order but exhibits a mass gap of the order of 1 GeV. From the distribution of color spins we reconstruct approximate effective actions by means of exact lattice Schwinger-Dyson and Ward identities ("inverse Monte Carlo"). We show that the generated ensemble cannot be recovered from a Faddeev-Niemi action, modified in a minimal way by adding an explicit symmetry-breaking term to avoid the appearance of Goldstone modes.Comment: 25 pages, 17 figures, JHEP styl

Clinical relevance and treatment possibilities of bipolar rapid cycling

Bipolar rapid cycling (RC) is defined as 4 or more affective episodes within 1 year. It has been postulated that RC is related to a poor response to lithium, to the same extent as mixed episodes or other atypical symptoms of the illness. This article reviews the current status of alternative pharmacological or otherwise supportive therapies of RC. Biological parameters and characteristics of the illness associated with RC like gender prevalence in women, hyperthyroid ism, catecholamine-O-methyltransferase allele, the influence of sleep, different subtypes of bipolar disorder and the risk of antidepressant-induced cycling will be discussed in detail. Copyright (C) 2002 S. Karger AG, Basel

The Stanley Foundation Bipolar Network: Results of the naturalistic follow-up study after 2.5 years of follow-up in the German centres

The Stanley Foundation Bipolar Network (SFBN) is an international, multisite network investigating the characteristics and course of bipolar disorder. Methods (history, ratings and longitudinal follow-up) are standardized and equally applied in all 7 centres. This article describes demographics and illness characteristics of the first 152 German patients enrolled in them SFBN as well as the results of 2.5 years of follow-up. Patients in Germany were usually enrolled after hospitalisation. More than 72% of the study population suffered from bipolar I disorder and 25% from bipolar 11 disorder. The mean +/- SD age of the study participants was 42.08 +/- 13.5 years, and the mean SD age of onset 24.44 +/- 10.9 years. More than 40% of the sample reported a rapid-cycling course in history, and even more a cycle acceleration overtime. 37% attempted suicide at least once. 36% had an additional Axis I disorder, with alcohol abuse being the most common one, followed by anxiety disorders. During the follow-up period, only 27% remained stable, 56% had a recurrence, 12.8% perceived subsyndromal symptoms despite treatment and regular visits. 27% suffered from a rapid-cycling course during the follow-up period. Recurrences were significantly associated with bipolar I disorder, an additional comorbid Axis I disorder, rapid cycling in history, a higher number of mood stabilizers and the long-term use of typical antipsychotics. Rapid cycling during follow-up was only associated with a rapidcycling course in history, a higher number of mood stabilizers and at least one suicide attempt in history. Copyright (c) 2003 S. Karger AG, Basel

Two-Qubit Separability Probabilities and Beta Functions

Due to recent important work of Zyczkowski and Sommers (quant-ph/0302197 and quant-ph/0304041), exact formulas are available (both in terms of the Hilbert-Schmidt and Bures metrics) for the (n^2-1)-dimensional and (n(n-1)/2-1)-dimensional volumes of the complex and real n x n density matrices. However, no comparable formulas are available for the volumes (and, hence, probabilities) of various separable subsets of them. We seek to clarify this situation for the Hilbert-Schmidt metric for the simplest possible case of n=4, that is, the two-qubit systems. Making use of the density matrix (rho) parameterization of Bloore (J. Phys. A 9, 2059 [1976]), we are able to reduce each of the real and complex volume problems to the calculation of a one-dimensional integral, the single relevant variable being a certain ratio of diagonal entries, nu = (rho_{11} rho_{44})/{rho_{22} rho_{33})$. The associated integrand in each case is the product of a known (highly oscillatory near nu=1) jacobian and a certain unknown univariate function, which our extensive numerical (quasi-Monte Carlo) computations indicate is very closely proportional to an (incomplete) beta function B_{nu}(a,b), with a=1/2, b=sqrt{3}in the real case, and a=2 sqrt{6}/5, b =3/sqrt{2} in the complex case. Assuming the full applicability of these specific incomplete beta functions, we undertake separable volume calculations.Comment: 17 pages, 4 figures, paper is substantially rewritten and reorganized, with the quasi-Monte Carlo integration sample size being greatly increase

Bures Metrics for Certain High-Dimensional Quantum Systems

Hubner's formula for the Bures (statistical distance) metric is applied to both a one-parameter and a two-parameter series (n=2,...,7) of sets of 2^n x 2^n density matrices. In the doubly-parameterized series, the sets are comprised of the n-fold tensor products --- corresponding to n independent, identical quantum systems --- of the 2 x 2 density matrices with real entries. The Gaussian curvatures of the corresponding Bures metrics are found to be constants (4/n). In the second series of 2^n x 2^n density matrices studied, the singly-parameterized sets are formed --- following a study of Krattenthaler and Slater --- by averaging with respect to a certain Gibbs distribution, the n-fold tensor products of the 2 x 2 density matrices with complex entries. For n = 100, we are also able to compute the Bures distance between two arbitrary (not necessarily neighboring) density matrices in this particular series, making use of the eigenvalue formulas of Krattenthaler and Slater, together with the knowledge that the 2^n x 2^n density matrices in this series commute.Comment: 8 pages, LaTeX, 4 postscript figures, minor changes, to appear in Physics Letters

Bures volume of the set of mixed quantum states

We compute the volume of the N^2-1 dimensional set M_N of density matrices of size N with respect to the Bures measure and show that it is equal to that of a N^2-1 dimensional hyper-halfsphere of radius 1/2. For N=2 we obtain the volume of the Uhlmann 3-D hemisphere, embedded in R^4. We find also the area of the boundary of the set M_N and obtain analogous results for the smaller set of all real density matrices. An explicit formula for the Bures-Hall normalization constants is derived for an arbitrary N.Comment: 15 revtex pages, 2 figures in .eps; ver. 3, Eq. (4.19) correcte