Comments on "New hypergeometric identities arising from Gauss’s second summation theorem"

In 1997, Exton [J. Comput. Appl. Math. 88 (1997) 269–274] obtained a general transfor- mation involving hypergeometric functions by elementary manipulation of series. A number of hypergeometric identities not previously recorded in the literature were then deduced by application of Gauss’ second summation theorem and other known hypergeometric summa- tion theorems. However, many of the results stated by Exton contain errors. It is the purpose of this note to present the corrected forms of these hypergeometric identities

Cell Cycle of Normal and Psoriatic Epidermis In Vitro

Studies of growth kinetics of normal and psoriatic epidermal cells in vitro indicate that there is no significant difference in the rate of proliferation under these conditions. The data may also be compatible with the hypothesis that both kinds of cells replicate at similar rates in vivo and that earlier conclusions regarding the markedly shortened cell cycle in psoriasis were based on insufficient data regarding the size of the proliferative pool in normal steady state epidermis

Functional outcome of arthroscopic reconstruction of anterior cruciate ligament tear using peroneus longus tendon autograft

Background: The objective of the study was to evaluate the functional outcome of arthroscopic reconstruction of ACL tear using triple layered PLT autograft and to study its effect on ankle stability.Methods: The study included 25 patients. The range of age was 18-42 years. Pre-op clinical tests and MRI was done to confirm tear. Reconstruction was done arthroscopically. Physiotheraphy protocol was fixed for all patients. Final outcome was assessed at 6 months using IKDC score and ankle stability was assessed by grading muscle power (MRC grading) with the normal side as control.Results: IKDC score was normal or near normal in 21 patients and only 4 patients were rated as abnormal or severely abnormal. Mean IKDC Score was 83.53. Stability of the ACL was assessed using the Lachman test: normal in 18 cases (72%), 1+ laxity in 5 cases (20%), 2+ and 3+ in 1 case (4%) each. Pivot shift was negative in 15 cases (60%), Pivot glide was seen in 9 cases (36%) and gross pivot shift was seen in 1 patient. Partial meniscectomy of the medial meniscus was performed in 5 patients. No patient experienced ankle dysfunction however 2 patients had pressure pain in the region of the graft harvest.Conclusions: PLT graft is similar to the native ACL both in terms of thickness and strength. It can be an appropriate autograft option for ACL reconstruction without compromising ankle function and avoiding potential complications of hamstring and BPTB autograft obtained from the knee region

Idiopathic clubfoot treated by Ponseti method: a series of 300 cases

Background: Clubfoot is a complicated deformity of the foot. It is one of the commonest congenital deformities in children. The main aim of this study was to evaluate the efficacy management of clubfoot by Ponseti method.Methods: This prospective study included 300 children (456 club feet) below the age of 2 years with idiopathic clubfeet from January 2013 to December 2017. In all the cases the Ponseti method was used for the management. The severity of the deformity was assessed with the help of the Pirani score and clinical evaluation of the foot was done.Results: Out of 300 patients 204 patients were male and 96 patients were female and 144 were unilateral clubfoot and 156 were bilateral cases of clubfoot. The mean number of casts required for correction was 5.4 (4–10). Out of 456 clubfeet 356 (78%) feet were required tenotomy. There was relapse seen in 36 (7.9%) feet which had to be managed with 2–3 serial manipulations and casting and these resolved. Excellent result found in our study in 92% cases, good results were found in 5% cases and poor results were found in 3% cases.Conclusions: Ponseti technique is a very useful and effective method of management of idiopathic clubfoot up to 2 year of age

Cognitive bias modification training in adolescents reduces anxiety to a psychological challenge

Many anxiety disorders begin in adolescence. Early interventions that target adolescent anxiety may prevent later disabling consequences. Previous studies show that cognitive bias modification training can generate positive interpretative styles of ambiguous information in adolescents but effects on anxious mood reduction are less clear. Adult studies suggest more consistent training effects on mood when assessed in response to a psychological challenge. Here, we assess whether positive training reduces adolescent anxious responses to a laboratory stressor. A total of 40 adolescents were randomly assigned to positive or negative computerised training. During training, ambiguous scenarios were resolved positively or negatively. After training, adolescents completed a test of interpretation bias and a difficult mental arithmetic task while believing that they were being videotaped for teaching purposes. First, positively-trained adolescents endorsed more positive and fewer negative interpretations of new ambiguous situations than negatively-trained adolescents. Second, positively-trained adolescents also showed attenuated anxiety levels after but not before the challenge. Induced positive interpretations via computerised cognitive training may modify anxious responsivity. Although there some caveats to these data, in general they justify extensions of computerised training to adolescents with clinical anxiety, to reduce anxious responsivity

Impact of coagulopathy in geriatric traumatic brain injury

Background: Traumatic brain injury (TBI) is the leading cause of death in trauma patients in various parts of the world including India. Coagulation cascade is affected in TBI.  The severity of coagulopathy correlates with degree of primary injuries thus affecting the prognosis of geriatric patients. Since the prognosis of isolated TBI can be a challenge to predict at times. AIM: we wanted to study the potential of international normalized ratio (INR) test, prothrombin test (PT), platelet count as a prognostic tool in isolated TBI. Methods: INR, PT, platelet count reflects the coagulation status. In most trauma cases, it is a routine test as well. We collected the INR, PT, platelet count value at admission of 200 isolated geriatric TBI cases over a period of three months. Then, patients were followed-up and their outcome at three months from admission is scored using Glasgow outcome scale (GOS). The relationship of INR, PT, platelet count with GOS was studied.Results: From our limited study, we found that INR of 1.52, PT 17 sec or more and platelet count less than 1.10 lac predicts poor prognosis in cases of isolated geriatric TBI.Conclusions: It is important to early diagnose and early manage the coagulation abnormalities in isolated geriatric head injury patients

From social machines to social protocols:Software engineering foundations for sociotechnical systems

The overarching vision of social machines is to facilitate social processes by having computers provide administrative support. We conceive of a social machine as a sociotechnical system (STS): a software-supported system in which autonomous principals such as humans and organizations interact to exchange information and services. Existing approaches for social machines emphasize the technical aspects and inadequately support the meanings of social processes, leaving them informally realized in human interactions. We posit that a fundamental rethinking is needed to incorporate accountability, essential for addressing the openness of the Web and the autonomy of its principals. We introduce Interaction-Oriented Software Engineering (IOSE) as a paradigm expressly suited to capturing the social basis of STSs. Motivated by promoting openness and autonomy, IOSE focuses not on implementation but on social protocols, specifying how social relationships, characterizing the accountability of the concerned parties, progress as they interact. Motivated by providing computational support, IOSE adopts the accountability representation to capture the meaning of a social machine’s states and transitions. We demonstrate IOSE via examples drawn from healthcare. We reinterpret the classical software engineering (SE) principles for the STS setting and show how IOSE is better suited than traditional software engineering for supporting social processes. The contribution of this paper is a new paradigm for STSs, evaluated via conceptual analysis

Comparative shoot regeneration in diploid and amphidiploid Brassica species and their interspecific hybrids

Shoot regeneration response in interspecific hybrids of Brassica species were assessed in relation to the diploid pollen parents and amphidiploid female parents. Superior regeneration responses were observed in interspecific combinations of B. carinata and B. nigra (BBC), B. juncea and B. campestris (AAB), and B. napus and B. campestris (AAC). Though synthetic B. napus regenerated with a frequency less than that of the better regenerating parent (B. oleracea), higher regeneration response was observed in the hybrid between B. napus and B. campestris. Two triploid combinations of the genetic constitution ABC, one obtained by crossing synthetic B. napus with B. nigra and the other by crossing natural B. juncea with B. oleracea, showed low regeneration responses. The response improved substantially in a tetraploid of the constitution ABBC obtained by crossing B. juncea with B. carinata. Key words: Brassica, alloploids, shoot regeneration

Proximal femoral nail- outcome and complications: a prospective study of 125 cases of proximal femoral fractures

Background: Fractures of the proximal femur are relatively common injuries in adults and common source of morbidity and mortality among the elderly. Fractures of the proximal femur include trochantric and subtrochantric fractures. The present study was designed to evaluate and analyze the role of proximal femoral nail (PFN) in the treatment of proximal femoral fractures.Methods: It was a prospective study on 125 cases of proximal femoral fractures. The fractures were classified according to AO classification. Salvati and Wilson Score were used for functional assessment.Results: In this study at 6 months follow up, union was achieved in 123 cases, open reduction was performed in 11% of cases (14 cases). Technical and mechanical complications were noted in 21% cases (27 cases). Reoperation rate was 4% (Five cases). According to Salvati and Wilson scoring system excellent results were seen in 36% of cases (45 cases), good results in 46% cases (58 cases), fair result in 13% cases (16 cases) and poor results in 5% cases (6 cases). Conclusions: It is concluded from our study that proximal femoral nailing is an attractive and suitable implant for Proximal Femoral Fractures and its use in unstable intertrochantric fractures is very encouraging