145 research outputs found

    Disorder-induced superconductivity in ropes of carbon nanotubes

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    We study the interplay between disorder and superconductivity in a rope of metallic carbon nanotubes. Based on the time dependent Ginzburg Landau theory, we derive the superconducting transition temperature Tc_c taking into account the critical superconducting fluctuations which are expected to be substantially strong in such low dimensional systems. Our results indicate that, contrary to what is expected, Tc_c increases by increasing the amount of disorder. We argue that this behavior is due to the dynamics of the tubes which reduces the drastic effect of the local disorder on superconductivity by enhancing the intertube Josephson tunneling. We also found that Tc_c is enhanced as the effective dimensionality of the rope increases by increasing the number N of the tubes forming the rope. However, Tc_c tends to saturate for large values of N, expressing the establishment of a bulk three dimensional (3D) superconducting order.Comment: 9 pages, 4 figur

    Antiferromagnetic Excitations and Van Hove Singularities in YBa2_2Cu3_3O6+x_{6+x}

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    We show that in quasi-two-dimensional dd-wave superconductors Van Hove singularities close to the Fermi surface lead to novel magnetic quasi-particle excitations. We calculate the temperature and doping dependence of dynamical magnetic susceptibility for YBCO and show that the proposed excitations are in agreement with inelastic neutron scattering experiments. In addition, the values of the gap parameter and in-plane antiferromagnetic coupling are much smaller than usually believed.Comment: REVTeX, 4 pages + 3 PostScript (compressed) figures; to appear in Phys. Rev. B (Rap. Comm.

    Reconstruction of discontinuous parameters in a second order impedance boundary operator

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    International audienceWe consider the inverse problem of retrieving the coefficients of a second order boundary operator from Cauchy data associated with the Laplace operator at a measurement curve. We study the identifiability and reconstruction in the case of piecewise continuous parameters. We prove in particular the differentiability of the Khon-Vogelius functional with respect to the discontinuity points and employ the result in a gradient type minimizing algorithm. We provide validating numerical results discussing in particular the case of unknown number of discontinuity points

    Inhomogeneous superconductivity in organic conductors: role of disorder and magnetic field

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    Several experimental studies have shown the presence of spatially inhomogeneous phase coexistence of superconducting and non superconducting domains in low dimensional organic superconductors. The superconducting properties of these systems are found to be strongly dependent on the amount of disorder introduced in the sample regardless of its origin. The suppression of the superconducting transition temperature TcT_c shows clear discrepancy with the result expected from the Abrikosov-Gor'kov law giving the behavior of TcT_c with impurities. Based on the time dependent Ginzburg-Landau theory, we derive a model to account for the striking feature of TcT_c in organic superconductors for different types of disorder by considering the segregated texture of the system. We show that the calculated TcT_c quantitatively agrees with experiments. We also focus on the role of superconducting fluctuations on the upper critical fields Hc2H_{c2} of layered superconductors showing slab structure where superconducting domains are sandwiched by non-superconducting regions. We found that Hc2H_{c2} may be strongly enhanced by such fluctuations.Comment: to appear in Journal of Physics: Condensed Matte

    Acute appendicitis: transcript profiling of blood identifies promising biomarkers and potential underlying processes

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    Background The diagnosis of acute appendicitis can be surprisingly difficult without computed tomography, which carries significant radiation exposure. Circulating blood cells may carry informative changes in their RNA expression profile that would signal internal infection or inflammation of the appendix. Methods Genome-wide expression profiling was applied to whole blood RNA of acute appendicitis patients versus patients with other abdominal disorders, in order to identify biomarkers of appendicitis. From a large cohort of emergency patients, a discovery set of patients with surgically confirmed appendicitis, or abdominal pain from other causes, was identified. RNA from whole blood was profiled by microarrays, and RNA levels were filtered by a combined fold-change (\u3e2) and p value (\u3c0.05). A separate set of patients, including patients with respiratory infections, was used to validate a partial least squares discriminant (PLSD) prediction model. Results Transcript profiling identified 37 differentially expressed genes (DEG) in appendicitis versus abdominal pain patients. The DEG list contained 3 major ontologies: infection-related, inflammation-related, and ribosomal processing. Appendicitis patients had lower level of neutrophil defensin mRNA (DEFA1,3), but higher levels of alkaline phosphatase (ALPL) and interleukin-8 receptor-ß (CXCR2/IL8RB), which was confirmed in a larger cohort of 60 patients using droplet digital PCR (ddPCR). Conclusions Patients with acute appendicitis have detectable changes in the mRNA expression levels of factors related to neutrophil innate defense systems. The low defensin mRNA levels suggest that appendicitis patient’s immune cells are not directly activated by pathogens, but are primed by diffusible factors in the microenvironment of the infection. The detected biomarkers are consistent with prior evidence that biofilm-forming bacteria in the appendix may be an important factor in appendicitis

    Ultrafast Laser-Based Spectroscopy and Sensing: Applications in LIBS, CARS, and THz Spectroscopy

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    Ultrafast pulsed lasers find application in a range of spectroscopy and sensing techniques including laser induced breakdown spectroscopy (LIBS), coherent Raman spectroscopy, and terahertz (THz) spectroscopy. Whether based on absorption or emission processes, the characteristics of these techniques are heavily influenced by the use of ultrafast pulses in the signal generation process. Depending on the energy of the pulses used, the essential laser interaction process can primarily involve lattice vibrations, molecular rotations, or a combination of excited states produced by laser heating. While some of these techniques are currently confined to sensing at close ranges, others can be implemented for remote spectroscopic sensing owing principally to the laser pulse duration. We present a review of ultrafast laser-based spectroscopy techniques and discuss the use of these techniques to current and potential chemical and environmental sensing applications

    The Val158Met COMT polymorphism is a modifier of the age at onset in Parkinson's disease with a sexual dimorphism

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    The catechol-O-methyltranferase (COMT) is one of the main enzymes that metabolise dopamine in the brain. The Val158Met polymorphism in the COMT gene (rs4680) causes a trimodal distribution of high (Val/Val), intermediate (Val/Met) and low (Met/Met) enzyme activity. We tested whether the Val158Met polymorphism is a modifier of the age at onset (AAO) in Parkinson's disease (PD). The rs4680 was genotyped in a total of 16 609 subjects from five independent cohorts of European and North American origin (5886 patients with PD and 10 723 healthy controls). The multivariate analysis for comparing PD and control groups was based on a stepwise logistic regression, with gender, age and cohort origin included in the initial model. The multivariate analysis of the AAO was a mixed linear model, with COMT genotype and gender considered as fixed effects and cohort and cohort-gender interaction as random effects. COMT genotype was coded as a quantitative variable, assuming a codominant genetic effect. The distribution of the COMT polymorphism was not significantly different in patients and controls (p=0.22). The Val allele had a significant effect on the AAO with a younger AAO in patients with the Val/Val (57.1±13.9, p=0.03) than the Val/Met (57.4±13.9) and the Met/Met genotypes (58.3±13.5). The difference was greater in men (1.9 years between Val/Val and Met/Met, p=0.007) than in women (0.2 years, p=0.81). Thus, the Val158Met COMT polymorphism is not associated with PD in the Caucasian population but acts as a modifier of the AAO in PD with a sexual dimorphism: the Val allele is associated with a younger AAO in men with idiopathic PD
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