Prediagnostic circulating concentrations of plasma insulin-like growth factor-I and risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition

Insulin-like growth factor-I (IG F-I) has cancer promoting activities. However, the hypothesis that circulating IGF-I concentration is related to risk of lymphoma overall or its subtypes has not been examined prospectively. IGF-I co ncentration was measured in pre-diagnostic plasma samples from a nested case-control study of 1072 cases of lymphoid malignancies and 1072 individually matched controls from th e European Prospectiv e Investiga tion into Cancer and Nutrition. Odds ratios (ORs) and c onfidence intervals (CIs) for lymphoma were calculated using conditional logist ic regression. IGF-I concentra tion was not associated with overall lymphoma risk (multivariable-adjusted OR for highest versus lowest third = 0.77 [95% CI=0.57-1.03], P trend = 0.06). There was no statistical evidence of heterogeneity in this association with IGF-I by se x, age at blood collection, tim e between blood collection and diagnosis, age at diagnosis, or body mass index (P heterogeneity for all ≥ 0.05). There were no associations between IGF-I c oncentration and risk for specific BCL subtypes, T-cell lymphoma or Hodgkin lymphoma, although number of cases were small. In this European population, IGF-I concentration wa s not associated with risk of overall lymphoma. This study provides the first prospective evidence on circ ulating IGF-I concentrations and risk of lymphoma. Further prospective data are re quired to examine asso ciations of IGF-I concentrations with lymphoma subtypes

Informal Home Care and Labor Force Participation of Household Members

In Germany, informal home care is preferred to professional care services in the public discussion as well as in legal care regulations. However, they ascribe only minor importance to the opportunity costs care givers have to face. Therefore, this paper explores the influence home care has on the labor supply of carers who live together with their care recipient. I am using the German Socio-Economic Panel of the years 2001 to 2007 which allows the characteristics of both groups to be merged. Furthermore, I look at female and male care givers separately. The results show that having an individual in need of care in the household does not decrease labor supply to an economically relevant extent. As caring and the labor supply decision might be endogenous, I test for endogeneity by using characteristics of care recipients as instruments and I look at sample attrition. In addition, the panel structure allows to control for unobserved heterogeneity, which is probably strong for care

Comparison of different methods for activation analysis of geological and pedological samples: Reactor and epithermal neutron activation, relative and monostandard method

SIGLEDEGerman

Etude et modelisation de la separation par adsorption en contre-courant simule

Available at INIST (FR), Document Supply Service, under shelf-number : RP 11203 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueSIGLEFRFranc