Investigation of experimental research on the low velocity impact damage behavior of ncf composite plates – COMPLAS XII

In this study an experimental investigation is performed on the impact response of non-crimp fabric composite plates at room temperature. Chopped strand mat combi is used as reinforcing material and two kinds of matrix; epoxy and polyester, are also used as resin material in the composite plates. All specimens used in experiments are manufactured by vacuum assisted resin infusion method at Atard Defence and Aerospace Advanced Technology Application Research and Development Inc. An instrumented drop weight impact testing machine Instron-Dynatup 9250 HV is used for impact testing. Impact tests are performed under various impact energies ranging from initiation of damage to final perforation. Damage processes of the samples are analyzed from cross-examining load– deflection curves, energy profiling method and damaged specimens

Lunar plume-surface interactions using rarefiedMultiphaseFoam

Understanding plume-surface interactions is essential to the design of lander modules and potential bases on bodies such as the Moon, as it is important to predict erosion patterns on the surface and the transport of the displaced regolith material. Experimentally, it is difficult to replicate the extra-terrestrial conditions (e.g. the effects of reduced gravity). Existing numerical tools have limited accessibility and different levels of sophistication in the modelling of regolith entrainment and subsequent transport. In this work, a fully transient open source code for solving rarefied multiphase flows, rarefiedMultiphaseFoam, is updated with models to account for solid-solid interactions and applied to rocket exhaust plume-lunar regolith interactions. Two different models to account for the solid-solid collisions are considered; at relatively low volume fractions, a stochastic collision model, and at higher volume fractions the higher fidelity multiphase particle-in-cell (MPPIC) method. Both methods are applied to a scaled down version of the Apollo era lunar module descent engine and comparisons are drawn between the transient simulation results. It is found that the transient effects are important for the gas phase, with the shock structure and stand-off height changing as the regolith is eroded by the plume. Both models predict cratering at early times and similar dispersion characteristics as the viscous erosion becomes dominant. In general, the erosion processes are slower with the multiphase particle-in-cell method because it accounts for more physical effects, such as enduring contacts and a maximum packing limit. It is found that even if the initial volume fraction is low, the stochastic collision method can become unreliable as the plume impinges on the surface and compresses the regolith particles, invalidating the method’s assumption of only binary collisions. Additionally, it is shown that the breakdown of the locally free-molecular flow assumption that is used to calculate the drag and heat transfer on the solid particles has a strong influence on the temperatures that the solid particles obtain

Enthesis tissue engineering: biological requirements meet at the interface

Tendon-to-bone interface (enthesis) exhibits a complex multiscale architectural and compositional organization maintained by a heterogeneous cellular environment. Orthopedic surgeons have been facing several challenges when treating tendon pullout or tear from the bony insertion due to unsatisfactory surgical outcomes and high retear rates. The limited understanding of enthesis hinders the development of new treatment options toward enhancing regeneration. Mimicking the natural tissue structure and composition is still a major challenge to be overcome. In this review, we critically assess current tendon-to-bone interface tissue engineering strategies through the use of biological, biochemical, or biophysical cues, which must be ultimately combined into sophisticated gradient systems. Cellular strategies are described, focusing on cell sources and cocultures to emulate a physiological heterotypic niche, as well as hypoxic environments, alongside with growth factor delivery and the use of platelet-rich hemoderivatives. Biomaterial design considerations are revisited, highlighting recent progresses in tendon-to-bone scaffolds. Mechanical loading is addressed to uncover prospective engineering advances. Finally, research challenges and translational aspects are considered. In summary, we highlight the importance of deeply investigating enthesis biology toward establishing foundational expertise and integrate cues from the native niche into novel biomaterial engineering, aiming at moving today's research advances into tomorrow's regenerative therapies.Authors thank the support from the European Union Framework Programme for Research and Innovation HORIZON2020 [TEAMING Grant agreement No 739572 - The Discoveries CTR]; FCT–Fundação para a Ciência e a Tecnologia for the PhD grant of IC [PD/BD/128088/2016]; the Project NORTE-01-0145-FEDER-000021:“Accelerating tissue engineering and personalized medicine discoveries by the integration of key enabling nanotechnologies, marine-derived biomaterials and stem cells”, supported by Norte Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF) and the ERC Consolidator grant of ME [ERC-2017-CoG-772817]

Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation : Data From ROCKET AF

M. Kaste on työryhmän ROCKET AF Steering Comm jäsen.Background-Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all-cause mortality may guide interventions. Methods and Results-In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) study, patients with nonvalvular atrial fibrillation were randomized to rivaroxaban or dose-adjusted warfarin. Cox proportional hazards regression with backward elimination identified factors at randomization that were independently associated with all-cause mortality in the 14 171 participants in the intention-to-treat population. The median age was 73 years, and the mean CHADS(2) score was 3.5. Over 1.9 years of median follow-up, 1214 (8.6%) patients died. Kaplan-Meier mortality rates were 4.2% at 1 year and 8.9% at 2 years. The majority of classified deaths (1081) were cardiovascular (72%), whereas only 6% were nonhemorrhagic stroke or systemic embolism. No significant difference in all-cause mortality was observed between the rivaroxaban and warfarin arms (P=0.15). Heart failure (hazard ratio 1.51, 95% CI 1.33-1.70, P= 75 years (hazard ratio 1.69, 95% CI 1.51-1.90, P Conclusions-In a large population of patients anticoagulated for nonvalvular atrial fibrillation, approximate to 7 in 10 deaths were cardiovascular, whereasPeer reviewe

Hemangioma of the masseter muscle: report of a case

This condition constitutes 0.8% of all hemangiomas, 14% in the head and neck [1]. Skeletal muscle involvement was first described in 1843 by Listen [2]. The rarity of these tumors and the difficulty with diagnosis often leads to incomplete excision [3]. These are congenital lesions consisting of mesodermal nests of vasoformative tissue that gives rise to the vascular tree [4]. They may be exacerbated by trauma and reproductive hormones [3, 5]. They can resolve spontaneously [3, 4, 6]. They present as a palpable, rubbery mass in 98% of cases [4]. Occasionally, they are compressible and pulsate. Conventional X-rays show phleboliths, MRI scanning gives good soft tissue definition, but angiography reveals the vascular nature of the tumor [7]. Irradiation cautery, sclerosants, lasers, steroids and surgical excision have been used for treatment [3, 4, 6, 8, 12]. Total excision is the treatment of choice [4, 6, 10, 13, 14]

Investigation of experimental research on the low velocity impact damage behavior of ncf composite plates – COMPLAS XII

In this study an experimental investigation is performed on the impact response of non-crimp fabric composite plates at room temperature. Chopped strand mat combi is used as reinforcing material and two kinds of matrix; epoxy and polyester, are also used as resin material in the composite plates. All specimens used in experiments are manufactured by vacuum assisted resin infusion method at Atard Defence and Aerospace Advanced Technology Application Research and Development Inc. An instrumented drop weight impact testing machine Instron-Dynatup 9250 HV is used for impact testing. Impact tests are performed under various impact energies ranging from initiation of damage to final perforation. Damage processes of the samples are analyzed from cross-examining load– deflection curves, energy profiling method and damaged specimens

Wearable and Elastic Surface Coil for 1H Magnetic Resonance Imaging

2-s2.0-85103289108Wearable and elastic surface coil using a conductive and stretchable textile for magnetic resonance imaging (MRI) of breast was designed. A high-conductive silver thread was woven with elastofiber to create two elastic textile coils. Three phantoms with varying sizes and a resolution plate were also designed to validate the coil performance. Signal to noise ratios (SNR) were calculated for the phantoms with different planar cuts. Resolution plate hole diameter of 6 mm was clearly discernible on axial MR images. Despite its canonical circular geometry, the wearable and elastic textile coil with one channel only was successful. The elastic coil can improve clinical applications of MRI with larger filling factor and may provide better patient comfort. IEE

Angiolymphoid hyperplasia with eosinophilia: report of a large-sized scalp lesion

In this report, a case is presented with large recurrent, benign, vascular and proliferative lesion on the scalp. Complete surgical excision of the tumor mass and split thickness skin grafting of the defect had favorable results with no recurrences after 24-month follow-up

Sinan and his Age International Symposium 8-11 April 2010, Kayseri

19 papers presented in thematic sesions focused on differente aspects of Sinan and his Age