Automation of knowledge extraction for degradation analysis

Degradation analysis relies heavily on capturing degradation data manually and its interpretation using knowledge to deduce an assessment of the health of a component. Health monitoring requires automation of knowledge extraction to improve the analysis, quality and effectiveness over manual degradation analysis. This paper proposes a novel approach to achieve automation by combining natural language processing methods, ontology and a knowledge graph to represent the extracted degradation causality and a rule based decision-making system to enable a continuous learning process. The effectiveness of this approach is demonstrated by using an aero-engine component as a use-case

A Polyadenylation Factor Subunit Implicated in Regulating Oxidative Signaling in Arabidopsis thaliana

BACKGROUND: Plants respond to many unfavorable environmental conditions via signaling mediated by altered levels of various reactive oxygen species (ROS). To gain additional insight into oxidative signaling responses, Arabidopsis mutants that exhibited tolerance to oxidative stress were isolated. We describe herein the isolation and characterization of one such mutant, oxt6. METHODOLOGY/PRINCIPAL FINDINGS: The oxt6 mutation is due to the disruption of a complex gene (At1g30460) that encodes the Arabidopsis ortholog of the 30-kD subunit of the cleavage and polyadenylation specificity factor (CPSF30) as well as a larger, related 65-kD protein. Expression of mRNAs encoding Arabidopsis CPSF30 alone was able to restore wild-type growth and stress susceptibility to the oxt6 mutant. Transcriptional profiling and single gene expression studies show elevated constitutive expression of a subset of genes that encode proteins containing thioredoxin- and glutaredoxin-related domains in the oxt6 mutant, suggesting that stress can be ameliorated by these gene classes. Bulk poly(A) tail length was not seemingly affected in the oxt6 mutant, but poly(A) site selection was different, indicating a subtle effect on polyadenylation in the mutant. CONCLUSIONS/SIGNIFICANCE: These results implicate the Arabidopsis CPSF30 protein in the posttranscriptional control of the responses of plants to stress, and in particular to the expression of a set of genes that suffices to confer tolerance to oxidative stress

Measurements of azimuthal anisotropies of jet production in Pb+Pb collisions at root sNN=5.02 TeV with the ATLAS detector

The azimuthal variation of jet yields in heavy-ion collisions provides information about the path-length dependence of the energy loss experienced by partons passing through the hot, dense nuclear matter known as the quark–gluon plasma. This paper presents the azimuthal anisotropy coefficients v2, v3, and v4 measured for jets in Pb + Pb collisions at √ sNN = 5.02 TeV using the ATLAS detector at the LHC. The measurement uses data collected in 2015 and 2018, corresponding to an integrated luminosity of 2.2 nb−1. The vn values are measured as a function of the transverse momentum of the jets between 71 and 398 GeV and the event centrality. A nonzero value of v2 is observed in all but the most central collisions. The value of v2 is largest for jets with lower transverse momentum, with values up to 0.05 in mid-central collisions. A smaller, nonzero value of v3 of approximately 0.01 is measured with no significant dependence on jet pT or centrality, suggesting that fluctuations in the initial state play a small but distinct role in jet energy loss. No significant deviation of v4 from zero is observed in the measured kinematic region.G. Aad … P. Jackson … A.X.Y. Kong … J.L. Oliver … H. Potti … T.A. Ruggeri … A.S. Sharma … M.J. White … et al. [The ATLAS Collaboration

Search for new phenomena in multi-body invariant masses in events with at least one isolated lepton and two jets using root s = 13 TeV proton-proton collision data collected by the ATLAS detector

Published: July 26, 2023A search for resonances in events with at least one isolated lepton (e or μ) and two jets is performed using 139 fb⁻¹ of √s = 13 TeV proton-proton collision data recorded by the ATLAS detector at the LHC. Deviations from a smoothly falling background hypothesis are tested in three- and four-body invariant mass distributions constructed from leptons and jets, including jets identified as originating from bottom quarks. Model-independent limits on generic resonances characterised by cascade decays of particles leading to multiple jets and leptons in the final state are presented. The limits are calculated using Gaussian shapes with different widths for the invariant masses. The multi-body invariant masses are also used to set 95% confidence level upper limits on the cross-section times branching ratios for the production and subsequent decay of resonances predicted by several new physics scenarios.G. Aad ... E. K. Filmer ... P. Jackson ... A. X. Y. Kong ... H. Potti ... T. A. Ruggeri ... E. X. L. Ting ... M. J. White ... et al. (The ATLAS collaboration

Determination of the parton distribution functions of the proton using diverse ATLAS data from pp collisions at root s = 7, 8 and 13 TeV

This paper presents an analysis at next-to-next to-leading order in the theory of quantum chromodynamics for the determination of a new set of proton parton distribution functions using diverse measurements in pp collisions at √s = 7, 8 and 13 TeV, performed by the ATLAS experiment at the Large Hadron Collider, together with deep inelastic scattering data from ep collisions at the HERA collider. The ATLAS data sets considered are differential cross-section measurements of inclusive W± and Z/γ ∗ boson production, W± and Z boson production in association with jets, tt ¯ production, inclusive jet production and direct photon production. In the analysis, particular attention is paid to the correlation of systematic uncertainties within and between the various ATLAS data sets and to the impact of model, theoretical and parameterisation uncertainties. The resulting set of parton distribution functions is called ATLASpdf21.G. Aad … P. Jackson … A.X.Y. Kong … J.L. Oliver … H. Potti … T.A. Ruggeri … A.S. Sharma …E. X. L. Ting ... M.J. White … et al. (The ATLAS Collaboration

Measurements of the Higgs boson inclusive and differential fiducial cross-sections in the diphoton decay channel with pp collisions at s root = 13 TeV with the ATLAS detector

Published: August 2, 2022A measurement of inclusive and differential fiducial cross-sections for the production of the Higgs boson decaying into two photons is performed using 139 fb−1 of proton-proton collision data recorded at s√ = 13 TeV by the ATLAS experiment at the Large Hadron Collider. The inclusive cross-section times branching ratio, in a fiducial region closely matching the experimental selection, is measured to be 67 ± 6 fb, which is in agreement with the state-of-the-art Standard Model prediction of 64 ± 4 fb. Extrapolating this result to the full phase space and correcting for the branching ratio, the total cross-section for Higgs boson production is estimated to be 58 ± 6 pb. In addition, the cross-sections in four fiducial regions sensitive to various Higgs boson production modes and differential cross-sections as a function of either one or two of several observables are measured. All the measurements are found to be in agreement with the Standard Model predictions. The measured transverse momentum distribution of the Higgs boson is used as an indirect probe of the Yukawa coupling of the Higgs boson to the bottom and charm quarks. In addition, five differential cross-section measurements are used to constrain anomalous Higgs boson couplings to vector bosons in the Standard Model effective field theory framework.The ATLAS collaboration, G. Aad ... P.Jackson ... A.X.Y Kong ... H.Potti ... T.A. Ruggeri ... A.S.Sharma ... E.X.L.Ting ... M.J.White ... et al

Genome-Wide Survey and Expression Profiling of CCCH-Zinc Finger Family Reveals a Functional Module in Macrophage Activation

Previously, we have identified a novel CCCH zinc finger protein family as negative regulators of macrophage activation. To gain an overall insight into the entire CCCH zinc finger gene family and to evaluate their potential role in macrophage activation, here we performed a genome-wide survey of CCCH zinc finger genes in mouse and human. Totally 58 CCCH zinc finger genes in mouse and 55 in human were identified and most of them have not been reported previously. Phylogenetic analysis revealed that the mouse CCCH family was divided into 6 groups. Meanwhile, we employed quantitative real-time PCR to profile their tissue expression patterns in adult mice. Clustering analysis showed that most of CCCH genes were broadly expressed in all of tissues examined with various levels. Interestingly, several CCCH genes Mbnl3, Zfp36l2, Zfp36, Zc3h12a, Zc3h12d, Zc3h7a and Leng9 were enriched in macrophage-related organs such as thymus, spleen, lung, intestine and adipose. Consistently, a comprehensive assessment of changes in expression of the 58 members of the mouse CCCH family during macrophage activation also revealed that these CCCH zinc finger genes were associated with the activation of bone marrow-derived macrophages by lipopolysaccharide. Taken together, this study not only identified a functional module of CCCH zinc finger genes in the regulation of macrophage activation but also provided the framework for future studies to dissect the function of this emerging gene family

Search for Higgs boson decays into a pair of pseudoscalar particles in the bb mu mu final state with the ATLAS detector in pp collisions at root s=13TeV

This paper presents a search for decays of the Higgs boson with a mass of 125 GeV into a pair of new pseudoscalar particles, H → aa, where one a-boson decays into a b-quark pair and the other into a muon pair. The search uses 139 fb−1 of proton-proton collision data at a center-of-mass energy of ffiffiffi sp¼ 13 TeVrecorded between 2015 and 2018 by the ATLAS experiment at the LHC. A narrow dimuon resonance is searched for in the invariant mass spectrum between 16 GeV and 62 GeV. The largest excess of events above the Standard Model backgrounds is observed at a dimuon invariant mass of 52 GeVand corresponds to a local (global) significance of 3.3σ (1.7σ). Upper limits at 95% confidence level are placed on the branching ratio of the Higgs boson to the bbμμ final state, BðH → aa → bbμμÞ, and are in the range 0.2–4.0 × 10−4, depending on the signal mass hypothesis.G. Aad ... P. Jackson ... H. Potti ... M.J. White ... et al. (ATLAS Collaboration