135 research outputs found
Comparative Osteology: A Cross-Species Study of First Rib Parameters and Their Relation to Body Mass with Emphasis on the Woolly Mammoth
Impact of habituated dietary protein intake on fasting and postprandial whole-body protein turnover and splanchnic amino acid metabolism in elderly men:a randomized, controlled, crossover trial
Glucagon-like peptide-1 elicits vasodilation in adipose tissue and skeletal muscle in healthy men
In healthy subjects, we recently demonstrated that during acute administration of GLPâ1, cardiac output increased significantly, whereas renal blood flow remained constant. We therefore hypothesize that GLPâ1 induces vasodilation in other organs, for example, adipose tissue, skeletal muscle, and/or splanchnic tissues. Nine healthy men were examined twice in random order during a 2âhour infusion of either GLPâ1 (1.5Â pmol kg(â1)Â min(â1)) or saline. Cardiac output was continuously estimated noninvasively concomitantly with measurement of intraâarterial blood pressure. Subcutaneous, abdominal adipose tissue blood flow (ATBF) was measured by the (133)Xenon clearance technique. Leg and splanchnic blood flow were measured by Fick's Principle, using indocyanine green as indicator. In the GLPâ1 study, cardiac output increased significantly together with a significant increase in arterial pulse pressure and heart rate compared with the saline study. Subcutaneous, abdominal ATBF and leg blood flow increased significantly during the GLPâ1 infusion compared with saline, whereas splanchnic blood flow response did not differ between the studies. We conclude that in healthy subjects, GLPâ1 increases cardiac output acutely due to a GLPâ1âinduced vasodilation in adipose tissue and skeletal muscle together with an increase in cardiac work
Increased oral sodium chloride intake in humans amplifies selectively postprandial GLP-1 but not GIP, CCK, and gastrin in plasma
Comparing meteorological fields of the ENSEMBLES regional climate models with ERA-40-data over the North Sea
The Copenhagen Sarcopenia Study:lean mass, strength, power, and physical function in a Danish cohort aged 20-93 years
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