Study of Variables Involved in Male Infertility Identified in the Spermograms Assessed in Assisted Human Reproduction

Introduction: According to the World Health Organization, about 8 to 10% of couples worldwide have infertility problems and male internal aspects are the main reasons for half of occurrences of human sterility. Through the spermogram, it is possible to qualitatively and quantitatively analyze semen, contributing to the diagnosis of male fertile state. Objective: To study the relationship among sperm viscosity, concentration, motility and volume parameters and male infertility factors and to show the influence of the subject age on these seminal parameters. Methodology: A survey was conducted in the male infertility database of the Nascer Clinic (Recife / Pernambuco) of men aged 27 to 61 years, with a history of marital infertility, from 2018 to 2019. The subjects studied were grouped into categories according to the classification of the seminal parameters analyzed (volume, concentration, motility and viscosity) in their sperm. Student’s t-test was used for normal distribution and Mann-Whitney test for non-normal using the GraphPad Prism 8 program. Results: Among the studied individuals, there was a significant difference (p <0.05) between the populations with obstructive azoospermia and nonobstructive azoospermia and among the percentages of oligozoospermic individuals with obstructive azoospermia. The azoospermia group had a significantly higher average age than the normozoospermia group. Conclusions: This suggests that azoospermia is present in older men, compromising male fertility. Sperm testing should be performed by all men of childbearing age to investigate possible changes in the genesis of gametic cells