4 research outputs found

    Natural Dye of Beetroot

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    In this study, a simple and indirect spectrophotometric method for the quantification of atenolol in pharmaceutical formulations, utilizing a natural food dye extracted from red beet root, is presented. The process involves the oxidation of atenolol in a 1 mol/LHCl acidic medium, using an excess of potassium persulfate. Subsequently, the resulting tablet solution is employed to fade the red beetroot dye, and the solution is measured spectrophotometrically. The optimized reaction conditions consist of a 16 µg/mL atenolol solution, 2.1 mL (100 µg/mL) of potassium persulfate, and 5 mL (100 µg/mL) of red beetroot dye. Spectrophotometric measurements were performed at 535 nm, and the linear range for quantification was found to be 4–22 µg/mL (R2 = 0.9987). The method exhibited a limit of detection of 0.01 µg/mL. Notably, the proposed method was successfully applied to analyze various commercial brands of pharmaceutical formulations; yielding results consistent with those obtained using the pharmacopeia method. This research offers a valuable and accessible technique for atenolol quantification, demonstrating potential significance in pharmaceutical analysis and quality control processes

    Structural Characterization of Salts Using X-ray Fluorescence Technique: Experiments on Samples Collected from Kurdistan Region of Iraq

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    This study investigates the structure of 21 table salts that were collected from different local markets in the Kurdistan region of Iraq. The major trace elements and iodine concentrations in tablesalt are analyzed through the X-ray fluorescence (XRF) technique and the titration method, respectively. The study shows that using XRF spectral analysis, the collected table salt samples are rich in chlorine, sodium, and contain a lower percentage of bromine, strontium, tin, tellurium, and iodine. Moreover, these samples have a high percentage of sulfur and sirconium, where the molybdenum is >0.2%. Other elements such as zinc and copper are essential and found in low concentrations <0.0086% and 0.001%. Iodine is a trace element that is necessary nutrients for human life, and it is naturally present in some foods. Iodine deficiency is brought on by a lack of iodine consumption. Iodized salt is highly recommended as a source of iodine to prevent iodine deficiency disease. Iodine is added to table salt in two different ways, either through iodate or through iodine. The results show that only 25% of the salt samples have an adequate level of iodine, while the other samples have low or no iodine content. According to the World Health Organization, quality of salt depends on iodine concentration and other trace elements, which are necessary for human health

    Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1

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    10.1016/s0140-6736(21)00984-3The Lancet39810299503-52
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