70 research outputs found

    Evaluating the Relationship between Emotional Intelligence and Interactive Thinking in Improving Architectural Design Process

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    The idea of thinking in ​​architectural design has long been one of the hallmarks of this process. On the other hand, according to the new definitions of emotional intelligence in the field of psychology, it can be concluded that if the parameters of this phenomenon are used positively and effectively, it is possible to promote the architectural design process among architecture students. Thus, identifying the related areas between emotional intelligence and interactive thinking in the architectural design process can play a significant role in promoting the creativity of future architects. For this purpose, the present study investigates the mutual relationship between emotional intelligence and interactive thinking in order to promote creativity in the architectural design process. To this end, after identifying the necessary infrastructures to develop either of these two phenomena, a mutual relationship between these two phenomena is discussed. It should be noted that the present study is descriptive and analytical and the evaluation is done through a questionnaire among some students of architecture at Damavand University. The results indicate that there is a significant relationship between emotional intelligence parameters and interactive thinking prerequisites for developing creative skills in architectural design process

    Kirurško liječenje uvrnuća trećega očnog kapka - prikaz slučaja

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    This report describes the clinical presentation, treatment, and outcome of a dog with third eyelid scrolling associated with prolapse of the gland of the third eyelid, which was treated with a modified surgical technique, and determines whether this procedure preserves the functions of the third eyelid, reduces cartilage shortening, eliminates the recurrence and finally improves the vision. An 8-month-old male German shepherd dog was presented with ocular irritation and epiphora. Ophthalmic examination revealed an everted third eyelid associated with a prolapsed nictitans gland. We performed the Morgan pocket technique to reposition the prolapsed gland in the current case, and the incision of deformed cartilage was done simultaneously. The surgical outcome was excellent with no recurrence or other complications. The Morgan pocket technique is a suitable surgical technique, however we corrected eversion of third eyelid by cutting the central portion of the deformed cartilage rather than removing the whole or part of it. This work may provide an alternative surgical treatment of third eyelid scrolling in dog.Rad opisuje kliničku sliku, liječenje i ishod liječenja psa s izvrnućem trećega očnog kapka povezanog s prolapsom pripadajuće žlijezde. Primijenjena je modificirana kirurška tehnik kako bi se utvrdilo očuvanje funkcije trećega očnog kapka, smanjilo skraćivanje hrskavice, spriječio povratak bolesti i, konačno, poboljšao vid. Mužjak njemačkog ovčara u dobi od osam mjeseci imao je iritaciju oka i epiforu. Oftalmološki je pregled pokazao uvrnuće trećega očnog kapka povezano s prolapsom žlijezde za treptanje. Učinjena je tehnika Morganova džepa za repoziciju izvrnute žlijezde uz istodobnu inciziju deformirane hrskavice. Rezultat zahvata bio je izvrstan, bez povratka bolesti i drugih komplikacija. Tehnika Morganova džepa prikladna je kirurška tehnika, iako smo korigirali treći očni kapak izrezavši središnji dio deformirane hrskavice radije nego uklanjajući cijelu hrskavicu. Ovaj rad nudi alternativo kirurško liječenje uvrnuća trećega očnog kapka u psa

    Effects of transplanted mesenchymal stem cells isolated from Wharton’s jelly of caprine umbilical cord on cutaneous wound healing; histopathological evaluation

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    The aim of this study was to investigate the effects of transplanted Wharton’s jelly mesenchymal stem cells (WJMSCs) of caprine umbilical cord on cutaneous wound healing process in goat. After collection of caprine pregnant uterus of mixed breed goats from abattoir, the Wharton’s jelly (WJ) of umbilical cord was harvested. The tissues were minced in ventilated flasks and explant culture method was used for separating mesenchymal stem cells (MSCs). The isolated cells were immunostained for Actin protein, histochemically assayed for the presence of alkaline phosphatase activity, and analyzed for detection of matrix receptors (CD44) and hematopoetic lineage markers (CD34), using flow cytometery. After The isolated cells, 3×106 MSCs were stained with BrdU and prepared for transplantation to each wound. Four 3-cm linear full thickness skin incisions were made on both sides of thoracic vertebrate of four Raeini goats (two wounds on each side). The left wounds were implanted with MSCs in 0.6 ml of Phosphate buffer saline (PBS), and the right wounds considered as control group that received 0.6 ml of PBS. The samples were taken from the wounds 7 and 12 days after the wounding, and healing process was compared histologically between the two groups. Anti-BrdU staining showed that the transplanted cells were still alive in the wound bed during the study. The histopathological study revealed that re-epithelialization was complete at days 7 in treated wounds with WJMSCs, whereas in control wound the wounds still showed incomplete epithelialization 12 days after wounding. Also, microscopic evaluation showed less inflammation, thinner granulation tissue formation with minimum scar in the treated wounds in comparison with control wounds. In conclusion, this study demonstrates the beneficial effect of caprine WJMSCs in cutaneous wound healing in goat

    Clinical Report Multiple Cutaneous Inverted Papilloma in a German shepherd Dog

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    Abstract Case Description-In this clinical report, occurrence of a rare case of canine cutaneous inverted papilloma was discussed. A 4-year-old, intact, male German shepherd dog was presented with multiple skin lesions, located on the inguinal region near the root of penis, which have been progressively growing since two months ago. In close examination of the lesions multiple, firm, painful, and cup-shaped nodules in different sizes with a central pore filled with keratin were observed. Treatment and Outcome-Surgical excision and histological evaluation was done. Histologically this tumor was characterized by endophytic projections of the epidermis extending into dermis.Cytopathic effects included ballooning degeneration of keratinocytes, koilocytosis, irregularity of keratohyalin granules, and margination of nuclear chromatin. Numerous eosinophilic intranuclear inclusions were present within keratinocytes of endophytic lesion. Immunohistochemically, the tumor cells were intensely positive for pancytokeratin. On the basis of histopathological and clinical findings, the tumor was diagnosed as multiple cutaneous inverted papilloma. There was no recurrence or any other complications in post operative monitoring. Clinical Relevance-Inverted papillomas are relatively uncommon in dogs; whereas, the incidence of this tumor in the inguinal region is uncommon. Treatment of inverted papilloma was completed by surgical excision in ablating the tumor masses and preventing re-growth. 92 Case Description A 4-year-old, intact, male German shepherd dog was presented for treatment of multiple skin lesions, located on the inguinal region near the root of penis. The owner declared that the masses have been growing up rapidly through two months prior to presentation. On clinical examination; all vital signs (heart Rate, respiratory rate and rectal temperature) were in the normal range. On dermatological examination, multiple, firm, painful, and cup-shaped nodules in different sizes with a central pore filled with keratin were observed and the masses had well-demarcated border Treatment and Outcome Based on the clinical examination, cutaneous neoplasia was suspected and complete surgical excision of the masses was recommended. The dog was premedicated with 0/05 mg/kg acepromazine (KELA Laboratoria) intramusculary and anesthesia intravenously was induced with 10 mg/kg thiopental sodium (Sandoz) and was maintained with halothane 2% (Halothane BP, Nicholas Piramal). An elliptical incision was made in the skin around the lesion and the masses were dissected from subcutaneous tissues. The skin was sutured with Nylon (Monofil Polyamid, Supa) USP: 2/0 in interrupted suture pattern. Postoperative care included Cefazoline (Exir Pharmaceutrical Co.) at 20 mg/kg intramuscularly, every 12 hours for 3 days. The removed masses were fixed in 10% neutral buffered formalin, processed routinely, embedded in paraffin, sectioned at 5 µm thickness, stained with hematoxylin and eosin, and studied with a routine light microscope. Immunohistochemistry of additional section was performed with Avidin-Biotin complex method by using monoclonal antibodies for pancytokeratin antibody (1/500). Microscopic examination at the nodules revealed cupshaped epidermal proliferation with centripetal papillary projections into dermi

    Global, regional, and national mortality due to unintentional carbon monoxide poisoning, 2000–2021: results from the Global Burden of Disease Study 2021

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    Background Unintentional carbon monoxide poisoning is a largely preventable cause of death that has received insufficient attention. We aimed to conduct a comprehensive global analysis of the demographic, temporal, and geographical patterns of fatal unintentional carbon monoxide poisoning from 2000 to 2021. Methods As part of the latest Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), unintentional carbon monoxide poisoning mortality was quantified using the GBD cause of death ensemble modelling strategy. Vital registration data and covariates with an epidemiological link to unintentional carbon monoxide poisoning informed the estimates of death counts and mortality rates for all locations, sexes, ages, and years included in the GBD. Years of life lost (YLLs) were estimated by multiplying deaths by remaining standard life expectancy at age of death. Population attributable fractions (PAFs) for unintentional carbon monoxide poisoning deaths due to occupational injuries and high alcohol use were estimated. Findings In 2021, the global mortality rate due to unintentional carbon monoxide poisoning was 0·366 per 100 000 (95% uncertainty interval 0·276–0·415), with 28 900 deaths (21 700–32 800) and 1·18 million YLLs (0·886–1·35) across all ages. Nearly 70% of deaths occurred in males (20 100 [15 800–24 000]), and the 50–54-year age group had the largest number of deaths (2210 [1660–2590]). The highest mortality rate was in those aged 85 years or older with 1·96 deaths (1·38–2·32) per 100 000. Eastern Europe had the highest age-standardised mortality rate at 2·12 deaths (1·98–2·30) per 100 000. Globally, there was a 53·5% (46·2–63·7) decrease in the age-standardised mortality rate from 2000 to 2021, although this decline was not uniform across regions. The overall PAFs for occupational injuries and high alcohol use were 13·6% (11·9–16·0) and 3·5% (1·4–6·2), respectively. Interpretation Improvements in unintentional carbon monoxide poisoning mortality rates have been inconsistent across regions and over time since 2000. Given that unintentional carbon monoxide poisoning is almost entirely preventable, policy-level interventions that lower the risk of carbon monoxide poisoning events should be prioritised, such as those that increase access to improved heating and cooking devices, reduce carbon monoxide emissions from generators, and mandate use of carbon monoxide alarms.publishedVersio

    Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019

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    Background: Ending the global tobacco epidemic is a defining challenge in global health. Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally. Methods: We estimated the prevalence of smoking tobacco use and attributable disease burden for 204 countries and territories, by age and sex, from 1990 to 2019 as part of the Global Burden of Diseases, Injuries, and Risk Factors Study. We modelled multiple smoking-related indicators from 3625 nationally representative surveys. We completed systematic reviews and did Bayesian meta-regressions for 36 causally linked health outcomes to estimate non-linear dose-response risk curves for current and former smokers. We used a direct estimation approach to estimate attributable burden, providing more comprehensive estimates of the health effects of smoking than previously available. Findings: Globally in 2019, 1·14 billion (95% uncertainty interval 1·13–1·16) individuals were current smokers, who consumed 7·41 trillion (7·11–7·74) cigarette-equivalents of tobacco in 2019. Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. Globally in 2019, smoking tobacco use accounted for 7·69 million (7·16–8·20) deaths and 200 million (185–214) disability-adjusted life-years, and was the leading risk factor for death among males (20·2% [19·3–21·1] of male deaths). 6·68 million [86·9%] of 7·69 million deaths attributable to smoking tobacco use were among current smokers. Interpretation: In the absence of intervention, the annual toll of 7·69 million deaths and 200 million disability-adjusted life-years attributable to smoking will increase over the coming decades. Substantial progress in reducing the prevalence of smoking tobacco use has been observed in countries from all regions and at all stages of development, but a large implementation gap remains for tobacco control. Countries have a clear and urgent opportunity to pass strong, evidence-based policies to accelerate reductions in the prevalence of smoking and reap massive health benefits for their citizens. Funding: Bloomberg Philanthropies and the Bill & Melinda Gates Foundation
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