Catheter Related Leuconostoc Mesenteroides Bacteremia: A Rare Case and Review of the Literature

Herein we report the successful treatment of catheter related blood stream infections due to Leuconostoc mesenteroides with antibiotic lock therapy in addition to systemic treatment. With our case, we have shown that in the presence of catheter related blood stream infections, antibiotic lock therapy can be used as a therapeutic option to get successful results if the catheter cannot be removed or there are still positive cultures despite the systemic antibiotic therapy

A Cause of Fungemia in A Patient with Hematological Malignancy: Blastoschizomyces capitatus

Blastoschizomyces capitatus is a rare fungal pathogen that may lead to severe and fatal infections in patients with hematological malignancies.The risk factors for infections with this pathogen are hematological malignancy, cytotoxic chemotherapy, corticosteroid use, intravascular catheter use, and broad spectrum antibiotic use. In this case report, fungemia and pneumoniae due to B. capitatus is reported in a patient who is diagnosed with acute lymphoblastic leukemia and receiving chemotheraphy. Blood cultures became negative after treatment with liposomal amphotericin B. In immunosupressed patients with severe fungal infection, B. capitatus should be kept in mind and should be considered in the choice of treatment. Further studies are required for the determination of antifungal susceptibilities and susceptibility breakpoints for B. capitatus

Antimicrobial resistance patterns and serotype distribution among Salmonella enterica strains in Turkey, 2000-2002

Since Turkey currently lacks a national reference center for Salmonella infections, the present study was conducted to document the distribution of serotypes and antimicrobial resistance patterns among Salmonella enterica isolates recovered from clinical samples in ten Turkish provinces over a 2-year period. Among the 620 Salmonella enterica isolates recovered between 1 July 2000 and 30 June 2002, strains belonging to the serotypes Enteritidis (47.7%), Typhimurium (34.7%), Paratyphi B (6.0%), Typhi (2.9%), Paratyphi A (0.2%) and serogroup C (8.5%) were found. Resistance to multiple antimicrobial agents was particularly high among Salmonella Typhimurium isolates (76.7%), and resistance or decreased susceptibility to ciprofloxacin (MIC >= 0.125 mg/l) was demonstrated in Salmonella Paratyphi B, Salmonella Typhimurium and Salmonella Enteritidis strains. All of the Salmonella Typhi isolates were susceptible to ciprofloxacin. The results indicate that decreased susceptibility to ciprofloxacin is an emerging problem in Salmonella enterica in Turkey, particularly in multiresistant strains