48 research outputs found

    Novel synthesis of active metal oxide surface from a self-organising system of inorganic solids

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    Self-organising aqueous suspension of layers of cationic montmorillonite and anionic mixed metal layered hydroxides �MMLH. after thermal treatment at about 5008C gives active and well-dispersed layers of metal oxides over montmorillonite matrix exhibiting enhanced reactivity with gaseous reactants. Increased absorption of H2S by ZnO supported on montmorillonite matrix is given as an exampl

    Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance

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    The Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades are often activated by genetic alterations in upstream signaling molecules such as receptor tyrosine kinases (RTK). Integral components of these pathways, Ras, B-Raf, PI3K, and PTEN are also activated/inactivated by mutations. These pathways have profound effects on proliferative, apoptotic and differentiation pathways. Dysregulation of these pathways can contribute to chemotherapeutic drug resistance, proliferation of cancer initiating cells (CICs) and premature aging. This review will evaluate more recently described potential uses of MEK, PI3K, Akt and mTOR inhibitors in the proliferation of malignant cells, suppression of CICs, cellular senescence and prevention of aging. Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt/mTOR pathways play key roles in the regulation of normal and malignant cell growth. Inhibitors targeting these pathways have many potential uses from suppression of cancer, proliferative diseases as well as aging

    Sol–gel-derived multifunctional nanoporous ceramic membranes

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    International audienceThe sol-gel process offers a wide range of opportunities in terms of tailored nanostructures and nanoporous layers. Here, this is illustrated with various examples of sol-gel-derived multifunctional nanoporous membranes. Hierarchically porous silica membranes and the implementation of different strategies for their functionalization as catalytic membranes are first described. The second part deals with sol-gel-derived photocatalytic membranes and with sol-gel-derived nanoporous membranes enabling reversible chemisorption of hydrogen sulfide

    Céramiques et environnement - filtration, catalyse, adsorption et systèmes couplés – Partie I

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    Céramiques et environnement - filtration, catalyse, adsorption et systèmes couplés – Partie II

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    Photocatalytic membrane reactors: principle and opportunities for their integration and miniaturization

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    About the role of adsorption in inorganic and composite membranes

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    SON68 glass dissolution driven by magnesium silicate precipitation

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