Six cases during 2012-2015 and literature review of Chryseobacterium indologenes infections in pediatric patients.

C. indologenes is a widespread bacteria in the environment, especially hospitals and rarely reported human pathogen. The lowest frequency was reported in children under 5 years of age. Clinical manifestations of C. indologenes include nosocomial pneumoniae, biliary tract infection, peritonitis, surgical wound infection, intravasculer catheter related bacteremia, cellulitis, and primary bacteremia. There is knowledge gap in the management of C.indologenes infections, especially in children because of multiple antibiotic resistance and limited data for effective empirical treatment in the literature. In the published literature, a total of 16 cases of C. indologenes infections in the pediatric age group were found. Herein we presented our experience in six children with C. indologenes infections. Early and prompt management of C. indolegenes infections, particularly in children with mechanic ventilation, polymicrobial infections, and under two-years old age constitute a major importance because this factors seem to have a negative affect on the prognosis of infections caused by C. indologenes. Ciprofloxacin and TPM-SMX may be the good therapeutic choices for a combined initial empiric treatment of the patients.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author