113 research outputs found
Thrombolytic therapy in cerebral venous sinus thrombosis.
The use of thrombolytic agents to rapidly lyse the clot has emerged as a therapeutic modality, in concert with interventional neuroradiologic approaches to deliver the agent locally at the site of thrombosis. There are no randomized, double blind, placebo, controlled trials to support thrombolysis as a first line therapy in patients with cerebral venous sinus thrombosis compared to standard therapy using anticoagulation with weight based dose adjusted unfractionated Heparin. Numerous case reports and a single non randomized trial have shown that it is comparatively safe and may rescue patients who are deteriorating despite anticoagulation with unfractionated Heparin. Consideration must be given to the use of thrombolysis in this group. This is an approach that must be restricted to centers with considerable experience in neurointerventional therapy
LOAD: a pilot study of the safety of loading of aspirin & clopidogrel in acute ischaemic stroke and transient ischaemic attack. Is the loading dose of aspirin and clopidogrel a good alternative for patients with acute ischaemic stroke and TIA? How this will impact our clinical practice?
High dose atorvastatin after stroke or transient ischaemic attack (SPARCL)--does every stroke patient in Pakistan deserve a statin
My patient just had a transient ischaemic attack. Can I predict his risk for stroke? Is stroke inevitable or preventable
Is HAS-BLED score better than CHADS2 and HEMOR2RHAGES schemes in assessing 1 year risk of major bleed in atrial fibrillation patients?
Acute administration of rt-PA for acute stroke in Pakistani patients--what does the available evidence teach us
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