Acute onset isolated abducens paralysis after exposure to arc welding

Exposure to welding is associated with many diseases, especially some of the eye injuries. We present a 49-year-old male patient applied to us with the complaints of double vision and blurred vision for a week. The symptoms started after looking welding machine light for a few minutes without protective glasses. After excluding another cause, the diagnosis of idiopathic abducens paralysis was made. As a result of exposure to metals and ultraviolet radiation, conjunctival disorders, presbyopia, refractive errors, corneal damage, and retinal pathologies can be seen in patients. It is also known that UV is a stress factor that will initiate reactions that lead to apoptosis of neurons. We think that exposure to UV rays may have played a role in the possible etiological process in our case. The patient was followed up with conservative treatment and all symptoms resolve within a month

Relationship between subjective sleep quality and serum ghrelin level in idiopathic parkinson patients

YÖK Tez No: 692097İdiopatik Parkinson hastalığı (İPH), substantia nigra pars compacta'daki dopaminerjik nöronların dejenerasyonu ile karakterize kronik, ilerleyici, nörodejeneratif bir hastalıktır. Uylu problemleri parkinson hastalarını etkileyen önemli non-motor semptomlardandır. Pittsburgh Uyku Kalitesi İndeksi (PUKI) uyku kalitesini değerlendirmek için kullanılan ölçeklerden biridir . Ghrelin, büyüme hormunu sekretuar resöptörünün endojen bir ligandı olan popüler ismiyle "açlık hormonu" olarak bilinen bir peptittir. Uygun yöntemle ve uygun zamanda ölçüldüğünde ghrelinin erken evre Parkinson hastalarında bir biyobelirteç olabilceği literatürde bildirilmiştir. Bu amaçla , çalışmamızda İdiopatik Parkinson Hastalarında subjektif uyku kalitesinin ve bunun serum ghrelin ile olan ilişkisinin gösterilmesi amaçlanmıştır . Parkinson ve Hareket Hastalıkları polikliniğimizce takipli 63 Parkinson hastası ve sosyodemografik olarak benzer dağılıma sahip 59 sağlıklı gönüllü dahil edildi. Hastalarımızın %61,9 erkek , %38,1 i kadın olup yaş ortalaması 64,7 ydi. Hastalarımız Modifiye Hoehn ve Yahr Skalası (H&Y) ve Birleşik Parkinson Hastalığı Değerlendirme Ölçeği (BPHDÖ) ile değerlendirildi . Hasta ve sağlıklı gönüllülerin PUKI ölçeği tesbit edildi , ELISA yöntemi kullanılarak serum açlık ghrelin seviyelerine bakıldı. Çalışmamızda hasta ve kontrol grubunun PUKİ değerleri arasında anlamlı bir farklılık görüldü ( p = <0,001 ) ve Parkinson hastalarında PUKI değerleri daha yüksek saptandı , bunun yanında hastaların PUKI değerleri ile BPHDÖ Nonmotor puanları arasında anlamlı ve orta derecede korele ( r 0,517) bir ilişki tesbit edildi . Serum açlık ghrelin seviyeleri ile BPHDÖ motor ,BPHDÖ non motor , H&Y ve PUKI değerleri arasında istatistiksel olarak anlamlı bir ilişki bulunmadı. Daha fazla Parkinson hastasında açlık ghrelinin yanında postprandiyel değişik saatlerde ölçülen Ghrelinin seviyelerine bakılan ek çalışmalara ihtiyaç duyulmaktadır.Idiopathic Parkinson's disease (IPD) is a chronic, progressive, neurodegenerative disease caused by the degeneration of dopaminergic neurons in the substantia nigra pars compacta. Sleeping problems are an important non-motor symptom affecting Parkinson's patients. The Pittsburgh Sleep Quality Index(indeksin orjinal ismi böyle geçiyor) (PSQI) is one of the scales used to evaluate sleep quality. Ghrelin is a peptide popularly known as the "hunger hormone", which is an endogenous ligand of the growth hormone secretory receptor. It has been reported that ghrelin could be a biomarker in early stage Parkinson's patients when measured with the appropriate method and time. For this reason, this study aimed to show subjective sleep quality in Idiopathic Parkinson's Patients and its relationship with serum ghrelin level. 63 patients with Parkinson's disease and 59 healthy volunteers with similar sociodemographic distribution were included in this study. 61.9% of our patients are male and 38.1% are female. The mean age was 64.7 years. Our patients were evaluated with Modified Hoehn and Yahr Scale (H&Y), and Unified Parkinson's Disease Rating Scale (UPDRS) . The values of the patients and healthy volunteers were determined according to the PSQI scale. Serum fasting ghrelin levels were measured using the ELISA method. In our study, there was a significant difference between the patients and control groups in terms of PSQI values (p = <0.001), and PSQI values were found to be higher in Parkinson's patients. In addition, a significant and moderately correlated (r 0.517) relationship was found between the PSQI values and the UPDRS non-motor scores of the patients. There was no statistically significant relationship between serum fasting ghrelin levels and UPDRS motor, UPDRS non-motor, H&Y and PSQI values. Additional studies examining the levels of ghrelin measured at different postprandial times in addition to fasting ghrelin in more Parkinson's patients are needed

The effect of different blood groups on visual evoked potentials

Introduction and aim. Purpose of the study is to determine whether it is required to use different standards when evaluating visual evoked potential (VEP) measurements of healthy individuals with different blood groups. Material and methods. The study consisted of healthy individuals with different blood groups who have applied to the ophthalmology and neurology outpatient clinic of Düzce University Medical Faculty from January to December 2022. The patients went through detailed ophthalmologic examination and VEP test and only the ones with normal results were included to the study. Results. The study consisted of 119 individuals, with a blood group distribution of 30 A, 29 B, 30 AB and 30 O. VEP latency and amplitude changes were compared and no significant difference was observed within 4 groups in terms of P100 and N70 latency and amplitudes. There was N70 latency prolongation in Rh- group and this difference was found to be statistically significant (p=0.009). Rh+ group was found to be high in terms of P100 amplitudes and this was considered statistically significant (both p=0.023). Conclusion. There was no statistically significant difference in the VEP parameters of the individuals with the ABO blood groups hence same VEP normal values can be used for ABO blood groups