ジドウ シコウ オヨビ セイリテキ ヘンカ ニオケル シット ト イカリ ノ サイ ノ ケントウ

The purpose of this study was examine to the relationship between anger and jealousy in terms of automatic thoughts and physiological changes. The participants were 37 undergraduate students(14 males and 23 females). Measures used were the enviousness scale for elementary and junior high school pupils and the trait anger scale for the anger scales. The participants were divided into four groups(listed in order to anger, jealousy high-high, high-low, low-high, low-low)on the basis of their average scores on the enviousness scale and the trait anger scale. The participants were presented with anger and jealousy situations which were made into recorded speech. Then,ventricular rate, anger and jealousy levels, and automatic thoughts among presented situation were measured. Results showed that the ventricular rate in anger, jealousy situation were higher than the ventricular rate at rest. Moreover the ventricular rate in anger situation tended to be higher than in jealousy situations. Additionally, automatic thoughts at anger and jealousy situation were analyzed by text mining. Many of the automatic thoughts in anger situations were related to other people, and many of the automatic thoughts in jealousy situations were related to oneself, followed by a relation to others as a comparison. From these results, there was a difference between automatic thoughts in anger situation and automatic thoughts in jealousy situations. Plutichilk(1980) pointed out that feelings other than the fundamental feelings were produced by a combination of fundamental feelings or fundamental feeling combined with other components. This study suggested that jealousy was evoked with anger through comparison with others

Prognostic Impact of Cardio-renal-anemia Syndrome in Patients at Risk for Heart Failure from the IMPACT-ABI study

Article信州医学雑誌 68(3): 139-147(2020)journal articl

Dietary diversity and healthy lifestyle

The aim of this study was to clarify the characteristics of lifestyle and health awareness according to dietary diversity in a Japanese worksite population. The participants were 1,312 men and women aged 20 to 63 years who were living in Tokushima Prefecture, Japan during the period 2012-2013. We obtained anthropometric data and information on lifestyle characteristics using a self-administered questionnaire. Dietary intake was assessed using a food frequency questionnaire, and dietary diversity was determined using the Quantitative Index for Dietary Diversity (QUANTIDD). The characteristics of lifestyle and health awareness according to quartiles of the QUANTIDD score were assessed using the chi-square test and a general linear model. The higher the QUANTIDD score was, the larger were the proportions of participants who knew the appropriate amount of dietary intake and participants who referred to nutritional component information when choosing and / or buying food. Among participants with higher QUANTIDD scores, the proportion of participants who considered their current diet was good was high in women, whereas the proportion of participants who wanted to improve their diet in the future was high in men. Those results indicate that higher dietary diversity was related to better characteristics of lifestyle and awareness of health

Glycolysis Inhibition Inactivates ABC Transporters to Restore Drug Sensitivity in Malignant Cells

Cancer cells eventually acquire drug resistance largely via the aberrant expression of ATP-binding cassette (ABC) transporters, ATP-dependent efflux pumps. Because cancer cells produce ATP mostly through glycolysis, in the present study we explored the effects of inhibiting glycolysis on the ABC transporter function and drug sensitivity of malignant cells. Inhibition of glycolysis by 3-bromopyruvate (3BrPA) suppressed ATP production in malignant cells, and restored the retention of daunorubicin or mitoxantrone in ABC transporter-expressing, RPMI8226 (ABCG2), KG-1 (ABCB1) and HepG2 cells (ABCB1 and ABCG2). Interestingly, although side population (SP) cells isolated from RPMI8226 cells exhibited higher levels of glycolysis with an increased expression of genes involved in the glycolytic pathway, 3BrPA abolished Hoechst 33342 exclusion in SP cells. 3BrPA also disrupted clonogenic capacity in malignant cell lines including RPMI8226, KG-1, and HepG2. Furthermore, 3BrPA restored cytotoxic effects of daunorubicin and doxorubicin on KG-1 and RPMI8226 cells, and markedly suppressed subcutaneous tumor growth in combination with doxorubicin in RPMI8226-implanted mice. These results collectively suggest that the inhibition of glycolysis is able to overcome drug resistance in ABC transporter-expressing malignant cells through the inactivation of ABC transporters and impairment of SP cells with enhanced glycolysis as well as clonogenic cells

Impact of Ambulation Status in Patients with End-stage Renal Disease on Hemodialysis due to Diabetic Nephropathy : The PREDICT Study

Article信州医学雑誌 68(3): 131-138(2020)journal articl

臨地実習における教師のあり方の一考察 : ウィーデンバックの再構成を用いて

患者・学生・指導者(教師を含む)を中心とした複雑な人間関係の中で展開される臨地実習に教師という立場で学生に関わる中で,自分の中に「なぜ?」という気持ちを感じることが何度かあった。その自分の中の疑問を明解にするために一学生との自分自身の関わりをウィーデンバックが述べている援助者としての思考・感情を訓練するための「再構成」を基にふり返った。それにより自分の感情や思考を学生との関わりの中で建設的に活用できていないこともあることがわかった。このことから臨地実習において教師の関わりが,学生に学習者として自ら発展できるかに大きく影響していることがわかった。教師のあり方は,(1)学生の行動をよく見て,その時の自分の感情に注意を注ぎ,それを意識することが必要である(2)援助者としてとして真実の感情を建設的に活用し,学生に伝えていくことが大切である(3)学生に伝えた後,学生の反応を待ち,話をよく聴くことが必要である。When I took part as a teacher in the bedside and clinical practice, in which there were clients, students, and teachers, I sometimes though \u27why?\u27 In order to make clear this question, I looked back at the relationship between myself and students based on the reconstruction method which Wiedenbach described for the development of skills in thoughts and actions as a tutor. I found that I could not convey my ementions and my considerations effectively to the students. This method requires me to identify the teacher\u27s relationship with the students and to the develop the following skills ; it is important that a teacher should consious of her own feelings when she/he observes the students\u27 actions ; to be aware of the self in this moment and to recognize that a teacher must communicate with students and should listen to the students\u27 remarks