Identification of Patients With Early Rheumatoid Arthritis: Challenges and Future Directions

Rheumatoid arthritis (RA) is the most common form of inflammatory arthritis that affects the adult population. Early diagnosis and treatment are the cornerstones to prevent joint damage and avoid long-term costs and disability. This article reviews the limitations of the currently available tools for the evaluation of patients with early arthritis, including clinical assessment, serologic markers and imaging modalities. It also discusses gene expression analysis, a newer and potentially promising approach to the early diagnosis of RA

Osteoarthritis Genu Bilateral on 53 Years Old Woman with Grade II Hypertension

One of most health disorders experienced by elder is musculoskeletal disorder, especially osteoarthritis (OA). Ostearthritis is the most frequent joint disease and found in all over the world, including Indonesia. It is at second rank after cardiovascular disease. In Wales, England, there were 1.3 to 1.75 million people suffering OA. Data of WHO showed that in Indonesia the prevalence of OA was 8.1% out of total population. Some of them visited doctor for examinations (29%), while the rest (71%) consumed over-the-counter pain relievers. Its frequency at elder above 50 years was dominantly females than males. A woman, 53 years old, complaining pain at her knees. Pain sometimes on and off and it may decrease when patient took a rest. Knee stiffness occurred at morning especially when waking up, but it vanished in 30 minutes. Physical examination found blood pressure 180/110 mmHg; respiration rate, pulse, and body temperature were normal. Body mass index was 24.99 kg/m2. Eyes, ears, nose, mouth, neck, thorax, and abdomen examinations were normal. Local status examination found pain and crepitation at palpation genu bilateral. The patient was diagnosed with osteoarthritis genu bilateral with hypertension grade II. The patient was treated with medicamentose in form of mefenamat acid 500 mg (when the pain raised), amlodipine 1x5 mg. The patient was also provided with non-medicamentose in form of education about osteoarthritis, hypertension, low salt diet, importance of controlling risk factors, and routine health examination to health services

Structural styles of the Shuilikeng fault system in the central Taiwan mountain belt

The Shuilikeng fault system in the central Taiwan mountain belt forms the structural boundary between two different tectonostratigraphic zones: the Western Foothills to the W, and the Hsuehshan Range to the E. It comprises a steeply-dipping roughly north-striking transpressive fault zone with splays, folds and bifurcations linked to the main structure. The structural style of the Shuilikeng fault system changes from N to S; while to the N it is defined by diverging splay and non-cylindrical folds branching off the Shuilikeng fault, to the S its structure is dominated by east-striking right-lateral strike-slip faults in the Hsuehshan Range and by a rejoining splay with a composite kinematics in the Western Foothills. At the southernmost tip of the study area, the Shuilikeng fault is defined by a several hundred meters-wide high strain zone and the structural architecture of the Western Foothills is that of a regional anticlinorium branching off the Shuilikeng fault intensely folded and faulted along its limbs.G. Camanni acknowledges the grant JAE-Predoc (CSIC). This research was carried out with the aid of the grant MICINN: CGL2009-11843-BTE.Peer Reviewe

Rituximab in rheumatology: single-centre SARS-CoV-2 infection and COVID-19 prevalence.

We describe a coronavirus disease 2019 (COVID-19) prevalence of 20% in rheumatic disease patients treated with rituximab, with 10.3% of these (2% of the entire cohort) having died of COVID-19-related causes

KAJIAN MITIGASI TSUNAMI BERBASIS VEGETASI DI PANTAI SEGER, KAWASAN EKONOMI KHUSUS MANDALIKA, PULAU LOMBOK

Pantai Seger  merupakan salah satu pantai yang berada di Kawasan Ekonomi Khusus (KEK) Mandalika, Pulau Lombok yang rentan terhadap bencana tsunami.  Apalagi vegetasi di Pantai Seger banyak mengalami degradasi. Oleh karena itu perlu dilakukan penelitian untuk mengetahui jenis-jenis tumbuhan (vegetasi) yang berpotensi dalam mitigasi tsunami di Pantai Seger, KEK Mandalika, Pulau Lombok. Penelitian dilakukan dengan metode eksplorasi (jelajah). Berdasarkan penelitian dapat diketahui bahwa tumbuhan yang berpotensi dalam mitigasi tsunami di Pantai Seger, KEK Mandalika, Pulau Lombok adalah Pandanus sp, Hibiscus tiliaceus, Rhizophora sp. dan Sonneratia sp

Structural styles of the Shuilikeng fault system in the central Taiwan mountain belt Estilos estructurales del sistema de fallas Shuilikeng en la parte central de la cordillera de Taiwan

Abstract: The Shuilikeng fault system in the central Taiwan mountain belt forms the structural boundary between two different tectonostratigraphic zones: the Western Foothills to the W, and the Hsuehshan Range to the E. It comprises a steeply-dipping roughly north-striking transpressive fault zone with splays, folds and bifurcations linked to the main structure. The structural style of the Shuilikeng fault system changes from N to S; while to the N it is defined by diverging splay and non-cylindrical folds branching off the Shuilikeng fault, to the S its structure is dominated by east-striking right-lateral strike-slip faults in the Hsuehshan Range and by a rejoining splay with a composite kinematics in the Western Foothills. At the southernmost tip of the study area, the Shuilikeng fault is defined by a several hundred meters-wide high strain zone and the structural architecture of the Western Foothills is that of a regional anticlinorium branching off the Shuilikeng fault intensely folded and faulted along its limbs. Key words: Taiwan, fault system, transpression. Resumen: El sistema de fallas Shuilikeng en la parte central de la cordillera de Taiwan forma el límite estructural entre dos zonas tectonoestratigráficas diferentes: las Wester

Variación temporal de glaciares en la Cordillera del Viento (Neuquén, Argentina) para el período 1963-2012

El estudio de los glaciares ha adquirido gran relevancia internacional, debido a su importante actuación como indicadores de cambio climático. Debido a la dificultad de su estudio, especialmente en regiones de difícil acceso, las investigaciones glaciológicas avanzaron gracias al desarrollo de tecnologías de sensoramiento remoto. Los avances recientes en fotogrametría permitieron reanalizar la información histórica existente, extendiendo los registros glaciológicos previos a la información de satélites ópticos de mediana/alta resolución con niveles de precisión aceptables. Las fotografías aéreas y las imágenes satelitales son actualmente herramientas complementarias, capaces de caracterizar y analizar fluctuaciones en geoformas glaciales. Los glaciares de la Patagonia argentina poseen trascendencia como reserva de agua dulce. Este trabajo presenta la reconstrucción histórica de los cuerpos de hielo existentes en la Cordillera del Viento para el período 1963-2012, para evaluar las fluctuaciones de los mismos. Se realizó un relevamiento de los glaciares en dicha cordillera, a partir de fotografías aéreas históricas de 1963 e imágenes satelitales de alta resolución disponibles en Google Earth para los años 2006 y 2012. A partir de la información, se analizaron parámetros morfométricos y morfológicos siguiendo lineamientos internacionales. Se relevaron 151 glaciares (5.94 km²) en 1963 y 29 (1.10 km²) en 2006-2012, reduciéndose significativamente en un -81.51% (-4.84 km²) la superficie emplazada por ellos en dicho período, a una tasa promedio de fusión de -0.10 km²/año. Los glaciares considerados como glaciaretes y con forma remanente, fueron los más afectados. No se consideraron en el presente estudio los cuerpos de hielos existentes en el Vn. Domuyo, ni aquellos con una superficie inferior a la mínima glaciar (≥0.01 km²).Eje: Ciencias Hidrológicas y Criósfera.Facultad de Ciencias Astronómicas y Geofísica