Study of clinical parameters and laboratory evaluation of metabolic syndrome in adolescents

Introduction: Worldwide incidence of obesity is rising. Genetic predisposition, urbanization, sedentary lifestyle, television watching, food habits, and lack of exercise are contributing factors. They result in obesity-related morbidity like metabolic syndrome, stroke in young, coronary artery disease, and diabetes. Materials and Methods: A cross-sectional study was undertaken among 1000 adolescents of both genders, aged 12-19 years in three schools of Pimpri, Pune, after obtaining approval from Institutional Ethical Committee. The criterion used to diagnose metabolic syndrome was International Diabetes Federation definition. The Chi-square test was used to explore the association between metabolic syndrome and various predictors. A P value of 0.05 was accepted as the level of statistical significance. Results: In the study sample, the prevalence of metabolic syndrome was 16/1000. Females were more likely to have metabolic syndrome (male:female = 7:9). Factors associated were body mass index (BMI), waist-hip ratio (WHR), birth weight, skin fold thickness, body fat percentage, faulty dietary habits, and sedentary lifestyles (P < 0.05). Among all, the components of metabolic syndrome, raised triglyceride (75%), and fasting blood sugar level (75%) were more prevalent than high-density lipoprotein-cholesterol (44%) and hypertension (37.5%). Conclusion: Metabolic syndrome was found to be more prevalent in females of age group 16-19 years, among the obese population, associated with birth weight, BMI, and WHR

Synthesis of new <i>O,O</i> -dialkyl-<i>O</i>-coumarinophosphorothioates and their pesticidal bioassay against <i>HeLicoverpa</i> <i>armigera</i>

339-341A series of compounds O,O-dialkyl-O-coumarinophosphorothioates have been synthesized and screened for pesticidal activities against HeLicoverpa armigera. Some of the compounds (3,4, 6 and 7) show significant activities while rest of the compounds show moderate activities

Sialosis: Cytomorphological significance in the diagnosis of an uncommon entity

A diffuse, chronic, usually bilateral, noninflammatory, nonneoplastic enlargement of major salivary glands is termed as Sialosis or Sialadenosis. It is an extremely uncommon cause for enlargement of the parotid gland. We hereby present a case of a 45-year-old female patient having a swelling at the left preauricular region. The swelling was gradually increasing in size since 6 months. On clinical examination, the swelling was 3 cm × 3 cm, mobile, and nontender. On ultrasonography, it was suggestive of benign parotid lesion or  parotitis with cervical lymphadenopathy. On fine needle aspiration cytology, it was suggestive of sialadenosis. This is an extremely rare salivary gland lesion with specific cellular features. It is very important to distinguish sialadenosis from other causes of enlargement of the parotid gland as treatment modality differs

PAPER PRINTED PHOTOVOLTAIC CELLS: EMERGING METHOD OF PV CELL PRODUCTION

An Solar energy is a renewable method for the energy production. The use of solar energy is increasing day by day and share of solar energy is increasing in the power sector of India. But as per pollution increases with energy consumption the need of solar energy will goes on increase in recent future as solar energy is a best option in both thermal and photovoltaic energy conversion processes. Photovoltaic cells are compact and has no movable parts which provides them effectiveness and easy handling. For providing further simplification the paper photovoltaic cells have been developed. This paper provides a review on the development and applications of paper photovoltaic cells

Case Report Congenital Thrombotic Thrombocytopenic Purpura: An Unusual Case of Microangiopathic Haemolytic Anaemia in a Newborn

ABSTRACT We present an extremely rare case of hyperbilirubinemia with rapid progression leading to bilirubin encephalopathy in term neonate. Despite early recognition and intervention, death occurred as a total serum bilirubin reached 25 mg/dl. It was a case of Coomb&apos;s negative microangiopathic haemolytic anaemia in a newborn period which is autosomal recessive inheritance i.e. Upshaw-Schulman Syndrome. (Congenital thrombotic thrombocytopenic purpura) characterised by numerous schistocytes on peripheral blood smear, thrombocytopenia , increased reticulocyte count, increased bilirubin and LDH level. This rare disease is often misdiagnosed especially in newborn baby. So we present this case not only for its variety but also for to create more awareness among pathologist and paediatrician as treatment protocol entirely differ

Light-driven Hydrogen Evolution from Water by a Tripodal Silane Based Co^II₆L¹₈ Octahedral Cage

The octahedral cage assembly [Co^II₆L¹₈Cl₆(H₂O)₆]­Cl₆ has been synthesized in a single-step reaction by using a polypyridyl-functionalized tripodal silane ligand. The electrochemical behavior of the cage in water exhibits the pH dependence of potential as well as catalytic current indicating the possible involvement of proton-coupled electron transfer in H₂ evolution. Electrocatalytic hydrogen evolution from an aqueous buffered solution gave a turnover frequency of 16 h^–1. Further, this cage assembly has been explored as a photocatalyst (blue light irradiation λ 469 nm) for the evolution of H₂ from water in the presence of Ru­(bpy)₃²⁺ as a photosensitizer and ascorbic acid as a sacrificial electron donor. This catalytic reaction is found to be pseudo first order with a turnover frequency of 20.50 h^–1

Green synthesis of silver nanoparticles via Aloe barbadensis miller leaves: Anticancer, antioxidative, antimicrobial and photocatalytic properties

Current work reports biogenic synthesis and physico-chemical characterization of silver nanoparticles (AgNPs) by using Aloe barbadensis miller leaves extract (ALE). The prepared biogenic AgNPs have been characterized physico-chemically by X-ray powder diffraction (XRD), UV-visible spectrometry, attenuated total reflectance infrared spectroscopy (ATR-IR), Atomic force microscopy (AFM) and Field emission- scanning electron microscopy (FE-SEM). The characteristic highest absorption peak at 439 nm confirmed the synthesis of AgNPs. Further, the biomedical and catalytic potential of AgNPs was investigated by their anticancer, antioxidative, antimicrobial, and photocatalytic properties. The anticancer potential of AgNPs was evaluated against the breast cancer (MCF-7) cells using MTT cytotoxicity assay. AgNPs proved to be anticancer even for the minimum concentrations of 10 µg/ml, and the anticancer efficiency was increased with increase in concentration. AgNPs showed 42.51% free radical scavenging activity due to their antioxidative nature. 0.3 M AgNPs showed maximum antimicrobial activity with 20 mm zone of inhibition against E. coli bacteria. Additionally, the AgNPs were tested for photocatalytic dye degradation of eosin, crystal violet, carbol fuchsin, methylene blue, and saffranine dyes with maximum % degradation 70.76%, 95.54%, 94.63%, 93.53%, and 90.12%, respectively. The study is unique as the biosynthesized silver nanoparticles by using Aloe barbadensis miller leaves extract shows promising anticancer, antioxidative, antimicrobial, and photocatalytic properties. Herein, the present study reveals the potential of biosynthesized AgNPs for improved therapeutic and catalytic applications

A Green Approach to the Synthesis of 5-Arylidene-2,4-thiazolidinediones Using Aqueous SDS Micelle Catalysis

A Green Approach to the Synthesis of 5-Arylidene-2,4-thiazolidinediones Using Aqueous SDS Micelle Catalysi