559 research outputs found
Bringing together emerging and endemic zoonoses surveillance: shared challenges and a common solution
Early detection of disease outbreaks in human and animal populations is crucial to the effective surveillance of emerging infectious diseases. However, there are marked geographical disparities in capacity for early detection of outbreaks, which limit the effectiveness of global surveillance strategies. Linking surveillance approaches for emerging and neglected endemic zoonoses, with a renewed focus on existing disease problems in developing countries, has the potential to overcome several limitations and to achieve additional health benefits. Poor reporting is a major constraint to the surveillance of both emerging and endemic zoonoses, and several important barriers to reporting can be identified: (i) a lack of tangible benefits when reports are made; (ii) a lack of capacity to enforce regulations; (iii) poor communication among communities, institutions and sectors; and (iv) complexities of the international regulatory environment. Redirecting surveillance efforts to focus on endemic zoonoses in developing countries offers a pragmatic approach that overcomes some of these barriers and provides support in regions where surveillance capacity is currently weakest. In addition, this approach addresses immediate health and development problems, and provides an equitable and sustainable mechanism for building the culture of surveillance and the core capacities that are needed for all zoonotic pathogens, including emerging disease threats
Search for Neutrinoless Double-Beta Decay in Xe with EXO-200
We report on a search for neutrinoless double-beta decay of Xe with
EXO-200. No signal is observed for an exposure of 32.5 kg-yr, with a background
of ~1.5 x 10^{-3} /(kg yr keV) in the region of interest. This
sets a lower limit on the half-life of the neutrinoless double-beta decay
(Xe) > 1.6 x 10 yr (90% CL),
corresponding to effective Majorana masses of less than 140-380 meV, depending
on the matrix element calculation
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Search for the disappearance of muon antineutrinos in the NuMI neutrino beam
We report constraints on antineutrino oscillation parameters that were obtained by using the two MINOS detectors to measure the 7% muon antineutrino component of the NuMI neutrino beam. In the Far Detector, we select 130 events in the charged-current muon antineutrino sample, compared to a prediction of 136.4 ± 11.7(stat)^(+10.2)_(-8.9)(syst) events under the assumption âÎm^2â = 2.32 X 10^(-3) eV^2, sin^2(2Ξ) = 1.0
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Measurement of the Neutrino Mass Splitting and Flavor Mixing by MINOS
Measurements of neutrino oscillations using the disappearance of muon neutrinos from the Fermilab NuMI neutrino beam as observed by the two MINOS detectors are reported. New analysis methods have been applied to an enlarged data sample from an exposure of 7.25Ă10^(20) protons on target. A fit to neutrino oscillations yields values of |Îm^2|=(2.32_(-0.08)^(+0.12))Ă10^(-3)ââeV^2 for the atmospheric mass splitting and sin^2(2Ξ)>0.90 (90% C.L.) for the mixing angle. Pure neutrino decay and quantum decoherence hypotheses are excluded at 7 and 9 standard deviations, respectively
Investigation of radioactivity-induced backgrounds in EXO-200
The search for neutrinoless double-beta decay (0{\nu}{\beta}{\beta}) requires
extremely low background and a good understanding of their sources and their
influence on the rate in the region of parameter space relevant to the
0{\nu}{\beta}{\beta} signal. We report on studies of various {\beta}- and
{\gamma}-backgrounds in the liquid- xenon-based EXO-200 0{\nu}{\beta}{\beta}
experiment. With this work we try to better understand the location and
strength of specific background sources and compare the conclusions to
radioassay results taken before and during detector construction. Finally, we
discuss the implications of these studies for EXO-200 as well as for the
next-generation, tonne-scale nEXO detector.Comment: 9 pages, 7 figures, 3 table
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