Meta-Analysis: Effects of Exposure to Tobacco Smoke and Malnutrition on the Risk of Pneumonia in Children

Background: Exposure to tobacco smoke (ETS) and poor nutritional status affect the risk of pneumonia in children. The purpose of this study was to analyze and estimate the effect of exposure to tobacco smoke and nutritional status in children on the risk of pneumonia. Subjects and Method: The meta-analysis was carried out using the PRISMA flowchart and the PICO model. Population: children under five. Intervention: exposure to tobacco smoke and poor nutritional status. Comparison: no exposure to tobacco smoke and no malnutrition status. Outcome: Pneumonia. The online databases used are Google Scholar, PubMed, and Scient Direct with the keywords “Pneumonia” AND “Exposure to tobacco smoke” AND “Poor nutritional status” AND “Children under five years” AND “Multivariate” AND “Cross-sectional”. The inclusion criteria were full-text, cross-sectional study, and published in English. The data were analyzed by RevMan 5.3. Results: A meta-analysis included 14 cross-sectional studies from Hong Kong, Nepal, Mongolia, Morocco, Uganda, Cameroon, Ethiopia, Nigeria, Egypt, and China. The total sample was 52,863 children under five. The results of the meta-analysis showed that exposure to tobacco smoke was 2.08 times more at risk of developing pneumonia than children under five who were not exposed (aOR=2.08; Cl 95%=1.30 to 3.32; p= 0.002). The presence of poor nutritional status is 2.00 times more at risk of experiencing pneumonia than children under five with no malnutrition status. (aOR=2.00; 95% Cl=1.31 to 3.06; p= 0.001). Conclusion: Exposure to tobacco smoke and poor nutritional status in toddlers can increase the risk of pneumonia. Keywords: exposure to tobacco smoke, poor nutritional status, children under five years pneumonia. Correspondence: Atika Dwi Minawati. Master’s Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Jawa Tengah, Indonesia. Email: [email protected]. Mobile: +625212613303

Effects of Insecticide-Treated Nets and Stagnant Water on the Risk of Malaria: A Meta-Analysis

Background: Malaria infection is a global public health problem that causes major morbidity worldwide. Stagnant water is one of the risk factors for malaria, insecticide-treated nets are one of the interventions that can prevent malaria. This study aims to estimate the magnitude of the effect of using insecticide-treated nets and stagnant water around the house on the risk of malaria. Subjects and Method: This study was conducted using a systematic review and meta-analysis with PICO, Population: children. Intervention: insecticide-treated mosquito nets and stagnant water. Comparison: without insecticide-treated nets and no stagnant water. Result: incidence of malaria. By searching for articles in 3 databases namely PubMed, Google Scholar, and Science Direct published from 2016 to 2023, by entering the following keywords insecticide-treated bed nets” OR “ITN” AND “stagnant water” OR “STAGNA” AND “Malaria” AND “Cross-sectional” AND “Multivariate Analysis”. Articles were selected using the PRISMA flow and data analysis using the Review Manager 5.3. Results: There are 13 articles using a cross-sectional study design with a total sample of 5,793 children from Indonesia, Cameroon, Nigeria, and Ethiopia which have gone through a systematic review and meta-analysis. Processed data showed that children who used insecticide-treated nets had a 0.65 times lower chance of contracting malaria compared to those who did not use insecticide-treated nets (aOR= 0.65; 95% CI= 0.41 to 1.01; p= 0.060). Children who live in an environment where there is stagnant water have a 4.10 times chance of getting malaria compared to children who live in an environment where there is no stagnant water and this is statistically significant (aOR= 4.10; 95% CI= 2.80 to 6.03; p <0.001). Conclusion: Insecticidal mosquito nets reduced the incidence of malaria, and stagnant water increased the incidence of malaria. Keywords: insecticide-treated nets, stagnant water, STAGNA, children Correspondence: Atika Dwi Minawati. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir Sutami No.36, Kentingan, Jebres, Surakarta, 57126, Central Java. Email: [email protected]. Mobile: +625212613303.

Effects of Insecticide-Treated Nets and Stagnant Water on the Risk of Malaria: A Meta-Analysis

Background: Malaria infection is a global public health problem that causes major morbidity worldwide. Stagnant water is one of the risk factors for malaria, insecticide-treated nets are one of the interventions that can prevent malaria. This study aims to estimate the magnitude of the effect of using insecticide-treated nets and stagnant water around the house on the risk of malaria. Subjects and Method: This study was conducted using a systematic review and meta-analysis with PICO, Population: children. Intervention: insecticide-treated mosquito nets and stagnant water. Comparison: without insecticide-treated nets and no stagnant water. Result: incidence of malaria. By searching for articles in 3 databases namely PubMed, Google Scholar, and Science Direct published from 2016 to 2023, by entering the following keywords insecticide-treated bed nets” OR “ITN” AND “stagnant water” OR “STAGNA” AND “Malaria” AND “Cross-sectional” AND “Multivariate Analysis”. Articles were selected using the PRISMA flow and data analysis using the Review Manager 5.3. Results: There are 13 articles using a cross-sectional study design with a total sample of 5,793 children from Indonesia, Cameroon, Nigeria, and Ethiopia which have gone through a systematic review and meta-analysis. Processed data showed that children who used insecticide-treated nets had a 0.65 times lower chance of contracting malaria compared to those who did not use insecticide-treated nets (aOR= 0.65; 95% CI= 0.41 to 1.01; p= 0.060). Children who live in an environment where there is stagnant water have a 4.10 times chance of getting malaria compared to children who live in an environment where there is no stagnant water and this is statistically significant (aOR= 4.10; 95% CI= 2.80 to 6.03; p <0.001). Conclusion: Insecticidal mosquito nets reduced the incidence of malaria, and stagnant water increased the incidence of malaria. Keywords: insecticide-treated nets, stagnant water, STAGNA, children Correspondence: Atika Dwi Minawati. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir Sutami No.36, Kentingan, Jebres, Surakarta, 57126, Central Java. Email: [email protected]. Mobile: +625212613303.