Association Between Nerve Conduction Velocity and Clinical Parameters Related to Diabetic Complications inPatients with Type 2 Diabetes

The main purpose of the study was to investigate the association of median motor nerve conduction velocity(MCV) and sural sensory nerve conduction velocity( SCV) with parameters related to diabetic complicationsin patients with type 2 diabetes. A total of 263 patients hospitalized for glycemic control from 1999to 2006 who underwent single or multiple nerve conduction velocity tests (at least a right median MCVtest) were enrolled in the study retrospectively. Right median MCV showed a significant negative correlationwith age and diabetic duration, and was also significantly negatively correlated with systolic blood pressure(SBP) and log urinary albumin excretion (UAE). Right median MCV showed strong positive correlationswith left median MCV and right median SCV, and significant but relatively mild positive correlationswith right peroneal MCV and right sural SCV. In multiple regression analysis, only SBP and diabetic durationshowed a significant association with right median MCV. Although right sural SCV showed significantnegative correlations with SBP and log UAE, the correlations were relatively weak compared with those forright median MCV. Of 215 patients who underwent complete sural SCV measurements, right and left suralSCV were detected in 159( 74%) and 163 patients( 76%), respectively. In conclusion, these results suggestthat median MCV is more closely associated with markers related to diabetic complications such as SBP orUAE, compared with sural SCV, but that sural SCV is more sensitive than median MCV for detection of diabeticneuropathy

地方都市中学生における食育課題の男子・女子間の比較検討

OBJECTIVE: We investigated dietary consciousness, dietary behavior, dietary environment and students feeling about their own health in Japanese male and female junior high school students, and examined the differences and similarities between the two gender groups to understand what we need to do in dietary education. METHODS: The survey was conducted during the month of October, 2006. Participants: The subjects were 477 junior high school boys (257) and girls (220) (age 12-14 years). Measure:1.We gave subjects a questionnaire of 68 questions asking about their perceptions of their own weight, dietary consciousnesses, dietary behavior, dietary environment, how healthy they believed themselves to be, and their lifestyles.2.Age, height and body weight were measured or supplied by the subjects teachers. Subjects whose weight was greater than or equal to 120% of the baseline degree of obesity as determined by the Ministry of Education were considered to have a tendency toward obesity, and subjects whose weight was less than or equal to 80% of the Ministry of Educations baseline degree of obesity were considered underweight. The TANITA scale was used and BMI was calculated based on the degree of obesity as established by the Japan Society for the Study of Obesity. RESULTS:1.Significant differences were observed between the two gender groups in the disparities between their classification of their own body types and their actual BMI scores (p<0.001). Many girls perceived themselves as overweight even though their weight was at an appropriate level.2.Significant differences were observed between the two groups in the subjective symptoms (p<0.001). Many girls claimed that their health condition was poor.3.Significant differences were observed between the two groups in their cooking skills (p<0.01). Fewer boys are able to cook than girls.4.Some other noteworthy results were obtained between the two groups about the degree of satisfaction with their lives and homes

地方都市と大都市における女子生徒の食育課題検出のための研究

OBJECTIVE: In this study we investigated dietary consciousness, dietary behavior, dietary environments, life-style and subjects evaluation of their own health in Japanese urban and suburban adolescents to get ideas for improving dietary education for these groups.METHODS: The survey was conducted in October and November, 2006. Participant: The subjects were 262 urban junior high school girls (Age 13-14 yrs) and 220 suburban junior high school girls (Age 12-14 yrs). Measure: 1.The questionnaire consisted of 76 questions related to subjects dietary behavior, dietary environments, lifestyles, and their evaluation of their own health.2.Age, height and body weight were measured by their teacher. Subjects body weight was checked using the TANITA scale. And subjects BMI was calculated based on the degree of obesity as established by the Japan Society for the Study of Obesity. RESULTS 1.In urban areas a lot of students thought that they are overweight. They perceived themselves to be overweight even when they were not.2.More students in urban areas than in suburban areas did not understand how much one should eat and what would constitute overeating. 3.More than 50% of both suburban and urban subjects reported feeling irritated. Subjects also reported experiencing headaches, stiff shoulders, and backaches.4.All subjects reported being basically satisfied with their lives and families.5.Significantly fewer urban subjects than suburban subjects reported having breakfast and supper with their families. 6.50% of both groups reported having conversations with their families during meals and that they are happy at home

Difluoro-C4′-oxidized Abasic Site for Efficient Amine Modification in Biological Systems

An oligodeoxynucleotide (ODN) containing a 2′,2′-difluorinated analogue of a C4′-oxidized abasic site (C4′-OAS) was designed for the amine modification of biomolecules that interact with nucleic acids. In contrast to the parent C4′-OAS, which yielded amine-modified products accompanied by DNA strand scission, the ODN containing the difluoro C4′-OAS efficiently yielded products carrying ODNs. The amine modification proceeded without additional reagents being required and might be applicable to reactions in biological systems