The Protective Role of Dehydroepandrosterone(DHEA) on the Reproductive Function in Adult Male Mice Treated with Nitrofurantoin

The aim to investigate the protective role of daily oral administration of the male reproduction system of mice treated with Nitrofurantoin. Forty eight adult albino mice were divided in to four equal groups as(G1)control , (G2) received 2mg/kg B.w of DHEA,(G3)received Nitrofurantoin at 200mg/kg B.w,(G4)received DHEA and Nitrofurantoin. All parameters were estimated after 30 and 60 day of the experiment. The result revealed the significant decrease testicular index, seminiferous tubules diameters, serum Testosterone and DHEAs level, sperm motility, viability and concentration in Nitrofurantoin treated mice with significant increase in sperm abnormality, serum catalase and peroxynitrite concentration. The opposite result were show in DHEA treated mice. Conclusion, DHEA at 2 mg/kg.B.w has a protective role in male reproduction system of Nitrofurantoin treated mice. This is suggested to be due to its potent antioxidative activity which is able to protect against Nitrofurantoin toxicity. Keywords: Nitrofurantoin, DHEA, male fertility, catalase, peroxynitrite

Roadmap on energy harvesting materials

Ambient energy harvesting has great potential to contribute to sustainable development and address growing environmental challenges. Converting waste energy from energy-intensive processes and systems (e.g. combustion engines and furnaces) is crucial to reducing their environmental impact and achieving net-zero emissions. Compact energy harvesters will also be key to powering the exponentially growing smart devices ecosystem that is part of the Internet of Things, thus enabling futuristic applications that can improve our quality of life (e.g. smart homes, smart cities, smart manufacturing, and smart healthcare). To achieve these goals, innovative materials are needed to efficiently convert ambient energy into electricity through various physical mechanisms, such as the photovoltaic effect, thermoelectricity, piezoelectricity, triboelectricity, and radiofrequency wireless power transfer. By bringing together the perspectives of experts in various types of energy harvesting materials, this Roadmap provides extensive insights into recent advances and present challenges in the field. Additionally, the Roadmap analyses the key performance metrics of these technologies in relation to their ultimate energy conversion limits. Building on these insights, the Roadmap outlines promising directions for future research to fully harness the potential of energy harvesting materials for green energy anytime, anywhere

Saccharine based carbonyl multi-walled carbon nanotubes: Novel modification, characterization and its ability for removing Cd(II) and Cu(II) from soil and environmental water samples

This research highlights the chemical modification of one of the carbon nanostructures (multi-walled carbon nanotubes-COOH) with an artificial sweetener (saccharine) to synthesize a highly efficient absorbent material (MWCNTs-CO-Sac). This material was thereafter used to the packing column in solid phase extraction of cadmium and copper divalent ions from real samples. This nano-adsorbent was diagnosed with different techniques: Infrared spectroscopy (FTIR), Thermogravimetry (TG), Differential thermal analysis (DTA), powder X-ray diffraction (PXRD), energy-dispersive X-ray spectroscopy (EDX), Particle size distribution (PSD) and scanning electron microscopy (SEM). The effect of pH, sample and eluent flow rates, volume, type and concentration of eluent, volume of sample and interfering ions were studied to achieve the optimal conditions for solid phase extraction of Cd(II) and Cu(II) based on the inductively coupled plasma-optical emission spectrometry (ICP-OES). Moreover, the preconcentration factors were calculated to be 75. The results of a limit of detection (LOD) 0.07 μgL-1 and 0.09 μgL-1 for Cd(II) and Cu(II) respectively. The relative standard deviation (RSD %) of this study was 0.45% for Cd(II) and 0.51% for Cu(II). The optimized method was applied to soil and environmental water samples. © 2019 Published under licence by IOP Publishing Ltd

Roadmap on energy harvesting materials

Abstract Ambient energy harvesting has great potential to contribute to sustainable development and address growing environmental challenges. Converting waste energy from energy-intensive processes and systems (e.g. combustion engines and furnaces) is crucial to reducing their environmental impact and achieving net-zero emissions. Compact energy harvesters will also be key to powering the exponentially growing smart devices ecosystem that is part of the Internet of Things, thus enabling futuristic applications that can improve our quality of life (e.g. smart homes, smart cities, smart manufacturing, and smart healthcare). To achieve these goals, innovative materials are needed to efficiently convert ambient energy into electricity through various physical mechanisms, such as the photovoltaic effect, thermoelectricity, piezoelectricity, triboelectricity, and radiofrequency wireless power transfer. By bringing together the perspectives of experts in various types of energy harvesting materials, this Roadmap provides extensive insights into recent advances and present challenges in the field. Additionally, the Roadmap analyses the key performance metrics of these technologies in relation to their ultimate energy conversion limits. Building on these insights, the Roadmap outlines promising directions for future research to fully harness the potential of energy harvesting materials for green energy anytime, anywhere

Roadmap on energy harvesting materials

Ambient energy harvesting has great potential to contribute to sustainable development and address growing environmental challenges. Converting waste energy from energy-intensive processes and systems (e.g. combustion engines and furnaces) is crucial to reducing their environmental impact and achieving net-zero emissions. Compact energy harvesters will also be key to powering the exponentially growing smart devices ecosystem that is part of the Internet of Things, thus enabling futuristic applications that can improve our quality of life (e.g. smart homes, smart cities, smart manufacturing, and smart healthcare). To achieve these goals, innovative materials are needed to efficiently convert ambient energy into electricity through various physical mechanisms, such as the photovoltaic effect, thermoelectricity, piezoelectricity, triboelectricity, and radiofrequency wireless power transfer. By bringing together the perspectives of experts in various types of energy harvesting materials, this Roadmap provides extensive insights into recent advances and present challenges in the field. Additionally, the Roadmap analyses the key performance metrics of these technologies in relation to their ultimate energy conversion limits. Building on these insights, the Roadmap outlines promising directions for future research to fully harness the potential of energy harvesting materials for green energy anytime, anywhere.M C thanks the Centre Québécois sur les Matériaux Fonctionnels (CQMF, a Fonds de recherche du Québec – Nature et Technologies strategic network) and A L thanks the Canada Research Chairs program for financial support. G C W thanks the University of Calgary. This work was authored in part by the National Renewable Energy Laboratory, operated by Alliance for Sustainable Energy, LLC, for the U.S. Department of Energy (DOE) under Contract No. DE-AC36-08GO28308 with writing support for BWL by ARPA-E DIFFERENTIATE program under Grant No. DE-AR0001215. The views expressed in the article do not necessarily represent the views of the DOE or the U.S. Government.Peer reviewe

Roadmap on energy harvesting materials

Funder: Fundação para a Ciência e TecnologiaFunder: BIDEKO ProjectFunder: MCIN/AEIFunder: Spanish State Research Agency (AEI)Funder: Basic Science Research ProgramFunder: Ministry of Education; doi: http://dx.doi.org/10.13039/501100002701Funder: Swedish Knowledge FoundationFunder: University of Calgary; doi: http://dx.doi.org/10.13039/100008459Funder: National Renewable Energy Laboratory; doi: http://dx.doi.org/10.13039/100006233Funder: Fonds de recherche du Québec – Nature et technologies; doi: http://dx.doi.org/10.13039/501100003151Funder: Canada Research Chairs programFunder: EUFunder: National Research Foundation of Korea; doi: http://dx.doi.org/10.13039/501100003725Funder: NRFFunder: Priority Research Centers ProgramFunder: European regional development fund (ERDF)Funder: European Research Council (ERC)Funder: ERCFunder: Alliance for Sustainable Energy, LLCFunder: MIURFunder: Italian MinistryFunder: the Cardiff University, Engineering and Physical Sciences Research CouncilFunder: JST Mirai ProgramFunder: Agence Nationale de la Recherche (ANR)Funder: A*STARFunder: JSTFunder: PRESTOFunder: Aerospace ProgrammeFunder: EBFunder: U.S. Department of Commerce, National Institute of Standards and TechnologyFunder: Laboratory-Directed Research and Development (LDRD)Funder: Sandia, LLCFunder: the Office of Science, Office of Basic Energy SciencesFunder: United States GovernmentFunder: Honeywell International Inc.Funder: The Leverhulme TrustFunder: Royal Academy of Engineering; doi: http://dx.doi.org/10.13039/501100000287Funder: Office of the Chief Science Adviser for National SecurityFunder: Henry Samueli School of Engineering & Applied ScienceFunder: Department of Bioengineering at the University of California, Los AngelesFunder: CRESTFunder: Beijing Forestry University; doi: http://dx.doi.org/10.13039/501100012138Funder: Japan Science and Technology Agency (JST)Funder: the Australian Research Council, QUTFunder: Center for Hierarchical Materials DesignFunder: Austrian Christian Doppler Laboratory for ThermoelectricityFunder: HBIS-UQ Innovation Centre for Sustainable SteelAbstract Ambient energy harvesting has great potential to contribute to sustainable development and address growing environmental challenges. Converting waste energy from energy-intensive processes and systems (e.g. combustion engines and furnaces) is crucial to reducing their environmental impact and achieving net-zero emissions. Compact energy harvesters will also be key to powering the exponentially growing smart devices ecosystem that is part of the Internet of Things, thus enabling futuristic applications that can improve our quality of life (e.g. smart homes, smart cities, smart manufacturing, and smart healthcare). To achieve these goals, innovative materials are needed to efficiently convert ambient energy into electricity through various physical mechanisms, such as the photovoltaic effect, thermoelectricity, piezoelectricity, triboelectricity, and radiofrequency wireless power transfer. By bringing together the perspectives of experts in various types of energy harvesting materials, this Roadmap provides extensive insights into recent advances and present challenges in the field. Additionally, the Roadmap analyses the key performance metrics of these technologies in relation to their ultimate energy conversion limits. Building on these insights, the Roadmap outlines promising directions for future research to fully harness the potential of energy harvesting materials for green energy anytime, anywhere.</jats:p

Roadmap on energy harvesting materials

Funder: Fundação para a Ciência e TecnologiaFunder: BIDEKO ProjectFunder: MCIN/AEIFunder: Spanish State Research Agency (AEI)Funder: Basic Science Research ProgramFunder: Ministry of Education; doi: http://dx.doi.org/10.13039/501100002701Funder: Swedish Knowledge FoundationFunder: University of Calgary; doi: http://dx.doi.org/10.13039/100008459Funder: National Renewable Energy Laboratory; doi: http://dx.doi.org/10.13039/100006233Funder: Fonds de recherche du Québec – Nature et technologies; doi: http://dx.doi.org/10.13039/501100003151Funder: Canada Research Chairs programFunder: EUFunder: National Research Foundation of Korea; doi: http://dx.doi.org/10.13039/501100003725Funder: NRFFunder: Priority Research Centers ProgramFunder: European regional development fund (ERDF)Funder: European Research Council (ERC)Funder: ERCFunder: Alliance for Sustainable Energy, LLCFunder: MIURFunder: Italian MinistryFunder: the Cardiff University, Engineering and Physical Sciences Research CouncilFunder: JST Mirai ProgramFunder: Agence Nationale de la Recherche (ANR)Funder: A*STARFunder: JSTFunder: PRESTOFunder: Aerospace ProgrammeFunder: EBFunder: U.S. Department of Commerce, National Institute of Standards and TechnologyFunder: Laboratory-Directed Research and Development (LDRD)Funder: Sandia, LLCFunder: the Office of Science, Office of Basic Energy SciencesFunder: United States GovernmentFunder: Honeywell International Inc.Funder: The Leverhulme TrustFunder: Royal Academy of Engineering; doi: http://dx.doi.org/10.13039/501100000287Funder: Office of the Chief Science Adviser for National SecurityFunder: Henry Samueli School of Engineering & Applied ScienceFunder: Department of Bioengineering at the University of California, Los AngelesFunder: CRESTFunder: Beijing Forestry University; doi: http://dx.doi.org/10.13039/501100012138Funder: Japan Science and Technology Agency (JST)Funder: the Australian Research Council, QUTFunder: Center for Hierarchical Materials DesignFunder: Austrian Christian Doppler Laboratory for ThermoelectricityFunder: HBIS-UQ Innovation Centre for Sustainable SteelAmbient energy harvesting has great potential to contribute to sustainable development and address growing environmental challenges. Converting waste energy from energy-intensive processes and systems (e.g. combustion engines and furnaces) is crucial to reducing their environmental impact and achieving net-zero emissions. Compact energy harvesters will also be key to powering the exponentially growing smart devices ecosystem that is part of the Internet of Things, thus enabling futuristic applications that can improve our quality of life (e.g. smart homes, smart cities, smart manufacturing, and smart healthcare). To achieve these goals, innovative materials are needed to efficiently convert ambient energy into electricity through various physical mechanisms, such as the photovoltaic effect, thermoelectricity, piezoelectricity, triboelectricity, and radiofrequency wireless power transfer. By bringing together the perspectives of experts in various types of energy harvesting materials, this Roadmap provides extensive insights into recent advances and present challenges in the field. Additionally, the Roadmap analyses the key performance metrics of these technologies in relation to their ultimate energy conversion limits. Building on these insights, the Roadmap outlines promising directions for future research to fully harness the potential of energy harvesting materials for green energy anytime, anywhere

Management of coronary disease in patients with advanced kidney disease

BACKGROUND Clinical trials that have assessed the effect of revascularization in patients with stable coronary disease have routinely excluded those with advanced chronic kidney disease. METHODS We randomly assigned 777 patients with advanced kidney disease and moderate or severe ischemia on stress testing to be treated with an initial invasive strategy consisting of coronary angiography and revascularization (if appropriate) added to medical therapy or an initial conservative strategy consisting of medical therapy alone and angiography reserved for those in whom medical therapy had failed. The primary outcome was a composite of death or nonfatal myocardial infarction. A key secondary outcome was a composite of death, nonfatal myocardial infarction, or hospitalization for unstable angina, heart failure, or resuscitated cardiac arrest. RESULTS At a median follow-up of 2.2 years, a primary outcome event had occurred in 123 patients in the invasive-strategy group and in 129 patients in the conservative-strategy group (estimated 3-year event rate, 36.4% vs. 36.7%; adjusted hazard ratio, 1.01; 95% confidence interval [CI], 0.79 to 1.29; P=0.95). Results for the key secondary outcome were similar (38.5% vs. 39.7%; hazard ratio, 1.01; 95% CI, 0.79 to 1.29). The invasive strategy was associated with a higher incidence of stroke than the conservative strategy (hazard ratio, 3.76; 95% CI, 1.52 to 9.32; P=0.004) and with a higher incidence of death or initiation of dialysis (hazard ratio, 1.48; 95% CI, 1.04 to 2.11; P=0.03). CONCLUSIONS Among patients with stable coronary disease, advanced chronic kidney disease, and moderate or severe ischemia, we did not find evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of death or nonfatal myocardial infarction