4,095 research outputs found

    An explorable public transcriptomics compendium for eukaryotic microalgae

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    Abstract Eukaryotic microalgae dominate primary photosynthetic productivity in fluctuating nutrient-rich environments, including coastal, estuarine and polar regions, where competition and complexity are presumably adaptive and dynamic traits. Numerous genomes and transcriptomes of these species have been carefully sequenced, providing an unprecedented view into the vast genetic repertoires and the diverse transcriptional programs operating inside these organisms. Here we collected, re-mapped, quantified and clustered publicly available transcriptome data for ten different eukaryotic microalgae in order to develop new insights into their molecular systems biology, as well as to provide a large new resource of integrated information to facilitate the efforts of others to further compare and contextualize the results of individual and new experiments within and between species. This is summarized herein and provided for public use by the eukaryotic microalgae research community

    A new device to treat intra-capsular fracture neck of femur non-union

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    In adolescents and young adults, femoral neck fractures often result from high-velocity trauma. These fractures are usually of vertical shear pattern. There is an increased incidence of avascular necrosis and non-union, which is difficult to treat. Non-union of fractured neck of femur in young adults is a serious problem. There is growing evidence that these fractures should be treated with an angle-stable device to improve biomechanics at the fracture site. An ideal implant should prevent varus deformation and retroversion of the fracture in order to prevent failure of the osteosynthesis and thus preventing cut-out of implant and non-union at the fracture site. We report the first use of an Orthofix Gottfried Percutaneous Compression Plate (PC.C.P.) (Orthofix, Guilford, UK) to treat a non-union of an intra-capsular fractured neck of femur. We recommend this, in combination with autologous bone grafting, via a mini hip modification of the Smith–Petersen approach

    Population Intermediate Outcomes of Diabetes Under Pay-for-Performance Incentives in England From 2004 to 2008

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    OBJECTIVE—To evaluate diabetes outcomes under a national “pay-for-performance” program

    Introduction: Public Places? Public Pasts?

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    Coherent State Approach to Quantum Clocks

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    The ``problem of time'' has been a pressing issue in quantum gravity for some time. To help understand this problem, Rovelli proposed a model of a two harmonic oscillators system where one of the oscillators can be thought of as a ``clock'' for the other oscillator thus giving a natural time reference frame for the system. Recently, the author has constructed an explicit form for the coherent states on the reduced phase space of this system in terms of Klauder's projection operator approach. In this paper, by using coherent state representations and other tools from coherent state quantization, I investigate the construction of gauge invariant operators on this reduced phase space, and the ability to use a quantum oscillator as a ``clock.''Comment: 13 pages, Late
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