781 research outputs found

    Causes and Consequences of Supply-Demand Gap for Labour in Sugarcane in India

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    The paper has estimated the demand for human labour use in sugarcane and other competing crops and changes over time in its use in major cane-growing states. It has also examined the supply-demand gap in human labour for sugarcane and has provided some coping strategies. The study, based on the primary as well as secondary data on the use of human labour for sugarcane for the past 30 years (1980 to 2010), has found that sugarcane cultivation is least mechanized and most labour-intensive in almost all major canegrowing states of India. The labour-use per hectare has increased in all the cane-growing states, except Tamil Nadu and Maharashtra. Study has revealed that the proportion of casual labour has increased over the years in sub-tropical states because of less availability of family labour for cane cultivation. The assured labour in the form of family + attached labour is on decline, impacting sugarcane cultivation adversely. Arduous work and inhuman working conditions, lack of female participation and disintegrating traditional system of cane harvesting have been identified as the major constraints for the increasing demand and supply gaps in sugarcane cultivation. The shortage of labour is reported to hit all sugarcane cultivation operations, driving up the costs and a decline in the profit margin of farmers. The study has also found that area under cane cultivation has reduced drastically in Haryana and cane yield is stagnant or declining in Maharashtra. The coping strategies for reducing demand-supply gap suggested in the paper are: R&D efforts towards development of sugarcane harvester; development of suitable crop geometry to facilitate the movement of machineries up to the knee-high stage of the crop; change in the traditional system of cane planting for fast germination to avoid weed menace and curtailing labour requirement; popularization of cane planting by machines developed at IISR, Lucknow and popularization of multifunctional ratoon management device. The sugar mills must evolve a sound cane development plan in their cane command areas for purchase of machinery and tie up with the manufacturers and research organizations. This will help in ensuring mechanization of cane operations and avoid forced scarcity of labour in situations of labour diversion to schemes like MGNREGS.Labour supply, Supply-demand gap, Labour demand, Sugarcane, Agricultural and Food Policy, J22, J23,

    Study of effective interaction from single particle transfer reactions on f-p shell nuclei

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    The present study concentrates on the average effective two-body interaction matrix elements being extracted, using sum-rule techniques, from transfer reactions on target states having single orbital as well as two orbitaloccupancy. This investigation deals with transfer reactions on f-p shell nuclei involving (i) 1f7/21f_{7/2} and 2p3/22p_{3/2} transfer on target states using 40^{40}Ca as inert core, and (ii) 2p3/22p_{3/2} and1f5/21f_{5/2} transfer on states using 56^{56}Ni as core.Comment: 12 pages, ptptex Subj-Classes: Nuclear Shell Structure e-mail:[email protected]

    Effective two-body interactions in the s-d shell nuclei from sum rules equations in tranfer reactions

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    Average effective two-body interaction matrix elements in the s-d shell have been extracted, from data on experimentally measured isospin centroids, by combining the recently derived new sum rules equations for pick-up reactions with similar known equations for stripping reactions performed on general multishell target states. Using this combination of stripping and pick-up equations, the average effective matrix elements for the shells, 1d^2_5/2, 2s^2_1/2 and 1d^2_3/2 respectively have been obtained. A new feature of the present work is that the restriction imposed in earlier works on target states, that it be populated only by active neutrons has now been abandoned.Comment: 12 pages, RevTeX, e-mail: [email protected]

    Clockwork for Neutrino Masses and Lepton Flavor Violation

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    We investigate the generation of small neutrino masses in a clockwork framework which includes Dirac mass terms as well as Majorana mass terms for the new fermions. We derive analytic formulas for the masses of the new particles and for their Yukawa couplings to the lepton doublets, in the scenario where the clockwork parameters are universal. When the Majorana masses all vanish, the zero mode of the clockwork sector forms a Dirac pair with the active neutrino, with a mass which is in agreement with oscillations experiments for a sufficiently large number of clockwork gears. On the other hand, when the Majorana masses do not vanish, neutrino masses are generated via the seesaw mechanism. In this case, and due to the fact that the effective Yukawa couplings of the higher modes can be sizable, neutrino masses can only be suppressed by postulating a large Majorana mass for all the gears. Finally, we discuss the constraints on the mass scale of the clockwork fermions from the non-observation of the rare leptonic decay μeγ\mu\rightarrow e\gamma.Comment: 11 pages, 7 figure

    Unification with Vector-like fermions and signals at LHC

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    We look for minimal extensions of Standard Model with vector like fermions leading to precision unification of gauge couplings. Constraints from proton decay, Higgs stability and perturbativity are considered. The simplest models contain several copies of vector fermions in two different (incomplete) representations. Some of these models encompass Type III seesaw mechanism for neutrino masses whereas some others have a dark matter candidate. In all the models, at least one of the candidates has non-trivial representation under SU(3)colorSU(3)_{color}. In the limit of vanishing Yukawa couplings, new QCD bound states are formed, which can be probed at LHC. The present limits based on results from 13 TeV already probe these particles for masses around a TeV. Similar models can be constructed with three or four vector representations, examples of which are presented.Comment: 48 pages; v3:major corrections with discussion on threshold corrections, version accepted for publication in JHE

    Enhanced susceptibility of cyclin kinase inhibitor p21 knockout mice to high fat diet induced atherosclerosis

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    Cyclin kinase inhibitor p21 is one of the most potent inhibitors of aortic smooth muscle cell proliferation, a key mediator of atherosclerosis. This study tests if p2l deficiency will result in severe atherosclerosis in a mouse model. p21-/- and strain matched wild type mice were fed with high fat diet for 21 weeks. Analysis for biochemical parameters (cholesterol, triglycerides) in serum and mRNA expression of CD36, HO-1, TGF-β, IFN-γ, TNF-α, PPAR-γ and NADPH oxidase components (p22phox, NOX-1 and Rac-1) was performed in aortic tissues by Real Time PCR. p21-/- mice gained significantly (p < 0.01) more weight than wild type mice, triglycerides (p < 0.05) and cholesterol levels (p < 0.01) were more pronounced in the sera of p21-/- compared to wild type mice fed with high fat diet. High fat diet resulted in significantly decreased TGF-β (p < 0.02), HO-l (p < 0.02) and increased CD36 (p < 0.03) mRNA expression in aortic tissues of p21-/- mice compared to animal fed with regular diet. IFN-γ mRNA expression (235 ± 11 folds) increased significantly in high fat diet fed p21-/- mice and a multifold modulation of PPAR-γ(136 ± 7), p22phox, NOX-1 and Rac-1 (15–35-folds) mRNA in aortic tissues from p21-/- mice compared to the wild type mice. Severity of atherosclerotic lesions was significantly higher in p21-/- compared to wild type mice. The results demonstrate that the deficiency of p21 leads to altered expression of pro-atherogenic genes, and severe atherosclerosis in mice fed with high fat diet. This opens the possibility of p21 protein as a therapeutic tool to control progression of atherosclerosis

    Reciprocal role of cyclins and cyclin kinase inhibitor p21(WAF1/CIP1 )on lymphocyte proliferation, allo-immune activation and inflammation

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    BACKGROUND: Immune activation that results due to the aberrant proliferation of lymphocytes leads to inflammation and graft rejection in organ transplant recipients. We hypothesize that the cell cycle control and inflammation are parallel events, inhibition of cellular proliferation by cyclin kinase inhibitor specifically p21 will limit inflammation and prevent allograft rejection. METHODS: We performed in vitro and in vivo studies using lymphocytes, and rat heart transplant model to understand the role of cyclins and p21 on mitogen and allo-induced lymphocyte activation and inflammation. Lymphocyte proliferation was studied by (3)H-thymidine uptake assay and mRNA expression was studied RT-PCR. RESULTS: Activation of allo- and mitogen stimulated lymphocytes resulted in increased expression of cyclins, IL-2 and pro-inflammatory cytokines, which was inhibited by cyclosporine. The over-expression of p21 prolonged graft survival in a completely mismatched rat heart transplant model resulted by inhibiting circulating and intra-graft expression of proinflammatory cytokines. CONCLUSION: Cyclins play a significant role in transplant-induced immune activation and p21 over-expression has potential to inhibit T cell activation and inflammation. The results from this study will permit the design of alternate strategies by controlling cell cycle progression to achieve immunosuppression in transplantation
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