A Rare Complication: Blue Urine Developed After Laparoscopic Chromopertubation

Methylene blue is a dye that is widely used in medicine. The underlyin reason this widespread use is that it is easily accessible, inexpensive and safe. Although rarely seen, some complications may develop during use of methylene blue. It is important that clinicians should be aware of these unwanted conditions, recognize these complications at an earlier stage, and take suitable measures

Wpływ rodności na kształt fali przepływu Dopplera w pierwszym trymestrze pojedynczej ciąży niskiego ryzyka

Objectives: The aim of the study was to evaluate the effect of parity on uteroplacental blood flow during the first trimester in low-risk singleton pregnancies. Materials and methods: Uterine artery Doppler examinations were performed in 190 singleton pregnancies between 11-14 gestational weeks. Twenty-five pregnancies were excluded from the study due to history of preeclampsia, diabetes mellitus or inherited thrombophilia. A total of 165 low-risk singleton pregnancies were included in the study. Mean uterine artery pulsatility index (PI) was recorded and compared between nulliparous and multiparous women. The relation between maternal age, gestational week, maternal weight, parity, biochemical markers and abnormal uterine artery Doppler flows was evaluated. T-test and logistic regression analyses were used for the statistical analysis. Results: A total of 165 singleton pregnancies without any risk factors for uteroplacental insufficiency were included in the study. Of them, 58 (36.7%) were nulliparous and 107 (63.3%) were parous. Correlation analysis revealed that the uterine artery pulsatility indices during the first trimester were not affected by maternal age and parity. Conclusions: Mean uterine artery pulsatility indices are not different in nulliparous and multiparous low risk pregnancies at 11-14 weeks of gestation.Cel: Celem badania była ocena wpływu rodności na przepływ maciczno-łożyskowy w pierwszym trymestrze pojedynczej ciąży niskiego ryzyka. Materiał i metoda: Przepływ w tętnicy macicznej zbadano w 190 pojedynczych ciążach w 11-14 tygodniu. Z analizy wyłączono 25 ciąż z powodu dodatniego wywiadu w kierunku stanu przedrzucawkowego, cukrzycy lub wrodzonej trombofilii. Ostatecznie do badania włączono 165 pojedynczych ciąż niskiego ryzyka. Zmierzono średni indeks pulsacji w tętnicy macicznej (PI), który porównano pomiędzy nieródkami i wieloródkami. Oceniono również związek pomiędzy wiekiem matki, wiekiem ciążowym, masą matki, liczbą porodów, markerami biochemicznymi a nieprawidłowym przepływem w tętnicach macicznych. T-test i regresji logistycznej zostały wykorzystane do analizy statystycznej. Wyniki: Do badania włączono 165 pojedynczych ciąż bez czynników ryzyka niewydolności maciczno-łożyskowej. Z tej grupy, 58 (36,7%) kobiet było nieródkami a 107 (63,3%) wieloródkami. Analiza statystyczna wykazała brak związku pomiędzy indeksem pulsacji w pierwszym trymestrze ciąży a wiekiem matki i rodnością. Wnioski: Średni indeks pulsacji w tętnicy macicznej nie różni się pomiędzy nieródkami a wieloródkami w ciąży niskiego ryzyka w 11-14 tygodniu

Abnormal Elevated CA 19-9 in the Dermoid Cyst: A Sign of the Ovarian Torsion?

Dermoid cyst is the most common germ cell tumor of the ovary containing various tissue elements. Ovarian torsion is a common complication of which ultrasonographic diagnosis is confusing. We report here a 14-year-old adolescent with painless torsion of the ovary including dermoid cyst and with abnormal elevated CA 19-9 serum levels. Elevated CA 19-9 level may be related to ovarian torsion and may predict the extent of tissue necrosis

Prenatal Diagnosis and Fetomaternal Outcomes of Two Cases with Placental Chorioangioma

Placental chorioangiomas greater than 4 cm in diameter are rare placental tumors. They have adverse fetomaternal outcomes. We present our experience with two cases having a giant angioma and review the relevant literature

Use of the modified myocardial performance index for evaluating fetal cardiac functions in pregestational diabetic pregnancy babies

The aim of this study is assessment of importance of use of the modified myocardial performance index (Mod-MPI) for the evaluation of foetal cardiac function in foetuses of women with pregestational diabetes mellitus (PDM). In this study, data of 30 pregnant patients aged 18–45 years diagnosed with PDM and 30 pregnant women aged 18–45 years with normal pregnancy and their babies were evaluated. Foetal echocardiographic and doppler measurements, foetal biometric measurements, umbilical artery and ductus venosus pulsatility indexes were measured in both PDM and control groups. The Mod-MPI was significantly higher in foetuses of PDM women. Many influences especially cardiac and postpartum complications are observed in infants of PDM women. The Mod-MPI is a simple and useful method for assessing foetal ventricular function. Our study has shown that PDM is associated with foetal ventricular dysfunction.Impact statement What is already known on this subject? Although MPI is frequently used in routine clinical assessment of neonates, it is not used adequately in foetuses. Many influences especially cardiac and postpartum complications are observed in infants of PDM women. However, there are few studies focussed specifically on the assessment of foetal cardiac function in PDM. What do the results of this study add? MPI, which shows both diastolic and systolic functions is independent of ventricular anatomy and foetal heart rate, was found significantly higher in diabetic mother foetuses, can be said to be a valuable parameter in evaluating foetal cardiac functions globally. What are the implications of these findings for clinical practice and/or further research? Our study has shown that foetuses PDM are associated with foetal ventricular dysfunction. For this MPI measurement can be routinely performed at foetal cardiac measurements in foetuses of PDM mothers

Maternal serum perlecan levels in women with preeclampsia

Objective: Perlecan is an extracellular matrix proteoglycan suggested to maintain endothelial functions. We aimed to measure maternal serum perlecan levels in different preeclampsia phenotypes. Methods: This study included 50 women with preeclampsia and 30 healthy pregnant women. Results: Serum perlecan levels were significantly higher (p = 0.016) in preeclamptic women with severe features(n = 23) than preeclampsia patients(n = 27). There were no statistically significant differences in serum perlecan levels between the early-onset preeclampsia(n = 25), late-onset preeclampsia(n = 25), and healthy pregnancies. Conclusion: Our findings suggest that preeclamptic women with severe features have higher serum perlecan levels than women with preeclampsia