82 research outputs found
Features of deviant behavior of junior schoolchildren with developmental disorders, depending on the prediction level
Social problems of modern society, tension of social relations, significant number of social deviation among children and youth determines the need for early prediction and prevention of socialization disorders of the younger generation. A particular risk group includes children wit h disabilities, which socialization takes place under special conditions, so the task of predicting the threats of their social development seems urgent. The aim of the study was to detect the relationship between the features of deviant behavior and the ability to anticipate future events in the junior schoolchildren with speech, hearing, vision, musculoskeletal system disorders. The study involved 274 schoolchildren aged from 8 to 11 years old (148 schoolchildren without developmental disorders, 126 schoolchildren with developmental disorders). The diagnostic study of schoolchildren was conducted by the method of expert evaluations by Achenbach, the "Guess" method by Peresleni and the "Anticipating the situation outcome with the norm violation" method by Ulyanova V.P. It was found that the ability to predict was determined by the level cognitive development of a child, presence/absence of somatic diseases, experience of social interaction. The anticipation of future events by junior schoolchildren with developmental disorders depends on the health and social experience. Prediction depends on the features of attention, ability to focus, as well as social experience and level of external problems in the schoolchildren without developmental disorders. The materials of this article can be useful for the specialists of educational organizations in the work on preventing behavioral disorders; for the specialists of rehabilitation centers that are engaged in correcting the social and cognitive functions of children with developmental disorders
Morphometric characteristics of Amaranthus caudatus L. In temperate continental climate
The new climate conditions of introduced plants are often very different from their original native places of growing. In this case, these conditions can be considered as stressful. Plants under adverse environmental conditions can adapt at the morphological, physiological, and biochemical levels. This paper discusses the morphological traits of Amaranthus caudatus L. cv. Edulis during introduction process in temperate continental climate. The results show that a combination of environmental factors (temperature, soil moisture, day length) affects the growth and development of plants. Amaranth has a wide response norm and adapts well to new conditions. The functional dependency between a lamina's area and a petiole's length is obtained. Β© 2021 Author(s).Ministry of Education and Science of the Russian Federation, Minobrnauka, (FEUZ-2020-0057)This work was supported by Ministry of Science and Higher Education of the Russian Federation as part of the state assignment number Κ FEUZ-2020-0057
Basket of Growth: New Export Industries in Sverdlovsk Region
The authors examine an export basket and reveal the new export goods for Sverdlovsk region, which might be used to transform the productive structure and upgrade export of the region. For each product, in which the region might develop its comparative advantage, the authors develop a measure of efforts, which are supposed to be made to include this good into the export basket, and a measure of the income level for the product. As a result the authors get a cluster of new and the most attractive export goods. Special methodology is used to choose the best cities to allocate the production of the new export goods.Export goods, comparative advantages, industrial cluster, production allocation
Non-silicate iron in mineral-associated organic matter of agro-chernozems located on different positions on the slope
Data on total non-silicate iron (Fed) content in mineral-associated organic matter (MAOM) of agro-chernozems of different localization on the slope are presented. The distribution of total non-silicate iron in soil profile follows that of organic carbon (OC): the maximum values are confined to the surface horizons, and decrease down the profile. It has been revealed that the change in the content of non-silicate iron in the MAOM of the clay fraction in arable horizons of eroded agro-chernozems is a result of erosion processes, including their intensity, which also depends, among other things, on the slope steepness. A lower slope steepness (4Β°) contributes to an increase in the organic carbon loading on iron oxides, resulting in an increased in iron desorption capacity, while a higher slope steepness (6Β°) results in lower iron desorption capacity. The OC/Fed molar ratio is suggested as an additional indicator of the degree of soil erosion. In clay fractions, of both their position in the soil profile and their position on the slope, the predominant mechanism of organic matter stabilization was the formation of organic-iron complexes (OC/Fed > 10). In the Residue fraction of humus horizons, non-silicate iron seems to be presented mainly as iron carbonates (FeCO3), while the proportion of microaggregates (stable under the sonication), where OM is mainly humin, is relatively low against the background of the absolute dominance of primary minerals in this fraction (weight %). Most of the non-silicate iron of mineralassociated OM extracted by dithionite-citrate-hydrocarbonate is localized in the clay fraction β 2/3 or more
DYNAMICS OF ORGANIC MATTER UNDER THE AFFORESTATION OF THE FORMER AGRICULTURAL SOD-PODZOLIC SOILS
The dynamics of the organic matter of the chronosequence of sod-podzolic soils in the process of reforestation has been investigated using the granulo-densitometric fractionation.The objects of research were sod-podzolic soils of the chronosequence of abandoned areas, including the main stages of the development of secondary succession: from overgrowing by grass vegetation to zonal spruce forests of the specially protected natural territory of the Central Forest State Natural Biosphere Reserve. In the first 20β25 years after the reduction of agrocenosis, degradation changes of the humus state of sod-podzolic soils were observed, due to the lack of agrotechnological treatments and the lack of fresh organic matter (OM) of cultivated plants. It is shown that only after 50 years functioning in the reservoir regime, the qualitative and quantitative indicators of organic matter of sod-podzolic soils begin to approach those of spruce forests of different species composition over 100 years old. This is manifested in an increase in the amount of discrete OM, the level of carbon accumulation of this fraction of OM in the soil and the value of its share in the total carbon accumulation in the soil
ΠΠ°ΡΡΠ½Π°Ρ ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΡΡΡ Β«ΠΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅, Π±ΠΈΠ±Π»ΠΈΠΎΠ³ΡΠ°ΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ ΠΈ ΠΊΠ½ΠΈΠ³ΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅Β» ΠΈ ΠΏΡΠΎΡΠΈΠ»ΡΠ½ΡΠ΅ Π΄ΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΠΎΠ½Π½ΡΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ (1999β2020)
In the modern world, global changes are taking place in all spheres of society, including economy, science, education and culture. In this regard, a detailed analysis and comprehension of ongoing processes become relevant to develop a specific strategy. In 2021, the Ministry of Science and Higher Education adopted the Order Β«On the approval of the nomenclature of scientific specialties for which scientific degrees are awarded <β¦.>β; the nomenclature of scientific specialties was published, where specialty 05.25.03 Β«Library Science, Bibliography science and BibliologyΒ» was not reflected (among pedagogical, historical, philological, technical sciences). This document came next to a draft nomenclature of scientific specialties (2020), which was widely discussed by the scientific community. The library community and representatives of university science carried out a number of activities aimed at changing the situation. The authors recreate the picture of forming and growing the profile scientific specialty, including its presentation in the nomenclature of scientific specialties for which scientific degrees are awarded since 1957; analyze statistic materials on post-graduate training of highly qualified scientific personnel and activity to defense dissertations in 1999β2020; generalize and assess the data, consider the problems and vectors of this specialty development to justify the inclusion of the specialty Β«Library Science, Bibliography Science and BibliologyΒ» in the new nomenclature of scientific specialties to continue the training of highly qualified scientific personnel in graduate school, and to carry out specialized research. The article argues that the consequences of the ongoing reforms in science have led to transformations, slowing down the rotation of scientific personnel, extinguishing the activities of dissertation councils and scientific schools in library science, bibliography and bibliology in the regions and complicating the development of library and information science in general.Π ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΌ ΠΌΠΈΡΠ΅ ΠΏΡΠΎΠΈΡΡ
ΠΎΠ΄ΡΡ Π³Π»ΠΎΠ±Π°Π»ΡΠ½ΡΠ΅ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ Π²ΠΎ Π²ΡΠ΅Ρ
ΡΡΠ΅ΡΠ°Ρ
ΠΎΠ±ΡΠ΅ΡΡΠ²Π°, Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ Π² ΡΠΊΠΎΠ½ΠΎΠΌΠΈΠΊΠ΅, Π½Π°ΡΠΊΠ΅, ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΠΈ ΠΈ ΠΊΡΠ»ΡΡΡΡΠ΅. Π ΡΠ²ΡΠ·ΠΈ Ρ ΡΡΠΈΠΌ ΡΡΠ°Π½ΠΎΠ²ΡΡΡΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΡΠΌΠΈ Π΄Π΅ΡΠ°Π»ΡΠ½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΈ ΠΎΡΠΌΡΡΠ»Π΅Π½ΠΈΠ΅ ΠΏΡΠΎΠΈΡΡ
ΠΎΠ΄ΡΡΠΈΡ
ΠΏΡΠΎΡΠ΅ΡΡΠΎΠ² Ρ ΡΠ΅Π»ΡΡ Π²ΡΡΠ°Π±ΠΎΡΠΊΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Π½ΠΎΠΉ ΡΡΡΠ°ΡΠ΅Π³ΠΈΠΈ. Π 2021 Π³. ΠΠΈΠ½ΠΈΡΡΠ΅ΡΡΡΠ²ΠΎΠΌ Π½Π°ΡΠΊΠΈ ΠΈ Π²ΡΡΡΠ΅Π³ΠΎ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°Π½ΠΈΡ Π±ΡΠ» ΠΏΡΠΈΠ½ΡΡ ΠΡΠΈΠΊΠ°Π· Β«ΠΠ± ΡΡΠ²Π΅ΡΠΆΠ΄Π΅Π½ΠΈΠΈ Π½ΠΎΠΌΠ΅Π½ΠΊΠ»Π°ΡΡΡΡ Π½Π°ΡΡΠ½ΡΡ
ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΡΡΠ΅ΠΉ, ΠΏΠΎ ΠΊΠΎΡΠΎΡΡΠΌ ΠΏΡΠΈΡΡΠΆΠ΄Π°ΡΡΡΡ ΡΡΠ΅Π½ΡΠ΅ ΡΡΠ΅ΠΏΠ΅Π½ΠΈ <β¦.>Β», ΠΎΠΏΡΠ±Π»ΠΈΠΊΠΎΠ²Π°Π½Π° Π½ΠΎΠΌΠ΅Π½ΠΊΠ»Π°ΡΡΡΠ° Π½Π°ΡΡΠ½ΡΡ
ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΡΡΠ΅ΠΉ, Π² ΠΊΠΎΡΠΎΡΡΡ ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΡΡΡ 05.25.03 Β«ΠΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅, Π±ΠΈΠ±Π»ΠΈΠΎΠ³ΡΠ°ΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ ΠΈ ΠΊΠ½ΠΈΠ³ΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅Β» (ΠΎΡΡΠ°ΡΠ»ΠΈ: ΠΏΠ΅Π΄Π°Π³ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅, ΠΈΡΡΠΎΡΠΈΡΠ΅ΡΠΊΠΈΠ΅, ΡΠΈΠ»ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅, ΡΠ΅Ρ
Π½ΠΈΡΠ΅ΡΠΊΠΈΠ΅ Π½Π°ΡΠΊΠΈ) Π½Π΅ Π±ΡΠ»Π° Π²ΠΊΠ»ΡΡΠ΅Π½Π°. ΠΠ²ΡΠΎΡΡ Π²ΠΎΡΡΠΎΠ·Π΄Π°ΡΡ ΠΊΠ°ΡΡΠΈΠ½Ρ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈ ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΈΡ ΠΏΡΠΎΡΠΈΠ»ΡΠ½ΠΎΠΉ Π½Π°ΡΡΠ½ΠΎΠΉ ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΡΡΠΈ, ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ΠΈΡ Π΅Π΅ Π² Π½ΠΎΠΌΠ΅Π½ΠΊΠ»Π°ΡΡΡΠ΅ Π½Π°ΡΡΠ½ΡΡ
ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΡΡΠ΅ΠΉ, ΠΏΠΎ ΠΊΠΎΡΠΎΡΡΠΌ ΠΎΡΡΡΠ΅ΡΡΠ²Π»ΡΠ΅ΡΡΡ ΠΏΡΠΈΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅ ΡΡΠ΅Π½ΡΡ
ΡΡΠ΅ΠΏΠ΅Π½Π΅ΠΉ, Π½Π°ΡΠΈΠ½Π°Ρ Ρ 1957 Π³., ΠΏΠΎΠ΄ΡΠΎΠ±Π½ΠΎ Π°Π½Π°Π»ΠΈΠ·ΠΈΡΡΡΡ ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΏΠΎ ΠΏΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠ΅ Π½Π°ΡΡΠ½ΡΡ
ΠΊΠ°Π΄ΡΠΎΠ² Π²ΡΡΡΠ΅ΠΉ ΠΊΠ²Π°Π»ΠΈΡΠΈΠΊΠ°ΡΠΈΠΈ Π² Π°ΡΠΏΠΈΡΠ°Π½ΡΡΡΠ΅, ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ Π·Π°ΡΠΈΡ Π΄ΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΠΉ Π² 1999β 2020 Π³Π³., ΠΎΡΡΡΠ΅ΡΡΠ²Π»ΡΡΡ ΠΎΠ±ΠΎΠ±ΡΠ΅Π½ΠΈΠ΅ ΡΠ²Π΅Π΄Π΅Π½ΠΈΠΉ, Π΄Π°ΡΡ ΠΈΠΌ ΠΎΡΠ΅Π½ΠΊΡ ΠΈ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°ΡΡ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ ΠΈ Π²Π΅ΠΊΡΠΎΡΡ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΡΡΠΈ Ρ ΡΠ΅Π»ΡΡ ΠΎΠ±ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΡ Π²ΠΊΠ»ΡΡΠ΅Π½ΠΈΡ ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΡΡΠΈ Β«ΠΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅, Π±ΠΈΠ±Π»ΠΈΠΎΠ³ΡΠ°ΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ ΠΈ ΠΊΠ½ΠΈΠ³ΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅Β» Π² Π½ΠΎΠ²ΡΡ Π½ΠΎΠΌΠ΅Π½ΠΊΠ»Π°ΡΡΡΡ Π½Π°ΡΡΠ½ΡΡ
ΡΠΏΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΡΡΠ΅ΠΉ, ΠΏΡΠΎΠ΄ΠΎΠ»ΠΆΠ΅Π½ΠΈΡ ΠΎΡΡΡΠ΅ΡΡΠ²Π»Π΅Π½ΠΈΡ ΠΏΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΊΠΈ Π½Π°ΡΡΠ½ΡΡ
ΠΊΠ°Π΄ΡΠΎΠ² Π²ΡΡΡΠ΅ΠΉ ΠΊΠ²Π°Π»ΠΈΡΠΈΠΊΠ°ΡΠΈΠΈ Π² Π°ΡΠΏΠΈΡΠ°Π½ΡΡΡΠ΅ ΠΈ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ ΠΏΡΠΎΡΠΈΠ»ΡΠ½ΡΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ. Π ΡΡΠ°ΡΡΠ΅ Π°ΡΠ³ΡΠΌΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½ΠΎ, ΡΡΠΎ ΠΏΠΎΡΠ»Π΅Π΄ΡΡΠ²ΠΈΡ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠΌΡΡ
ΡΠ΅ΡΠΎΡΠΌ Π² Π½Π°ΡΠΊΠ΅ ΠΏΡΠΈΠ²Π΅Π»ΠΈ ΠΊ ΡΡΠ°Π½ΡΡΠΎΡΠΌΠ°ΡΠΈΡΠΌ, Π·Π°ΠΌΠ΅Π΄Π»ΠΈΠ²ΡΠΈΠΌ ΡΠΎΡΠ°ΡΠΈΡ Π½Π°ΡΡΠ½ΡΡ
ΠΊΠ°Π΄ΡΠΎΠ², ΡΠ³Π°ΡΠ°Π½ΠΈΡ Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ Π΄ΠΈΡΡΠ΅ΡΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΡΠΎΠ²Π΅ΡΠΎΠ² ΠΈ Π½Π°ΡΡΠ½ΡΡ
ΡΠΊΠΎΠ» ΠΏΠΎ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ, Π±ΠΈΠ±Π»ΠΈΠΎΠ³ΡΠ°ΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ ΠΈ ΠΊΠ½ΠΈΠ³ΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ Π² ΡΠ΅Π³ΠΈΠΎΠ½Π°Ρ
ΠΈ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΡ ΡΠ°Π·Π²ΠΈΡΠΈΡ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΡΠ½ΠΎ-ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ Π½Π°ΡΠΊΠΈ Π² ΡΠ΅Π»ΠΎΠΌ
Biochemical composition of tomato fruits of various colors
Tomato (Lycopersicon esculentum Mill.) is an economically important and widely cultivated vegetable crop that is consumed both fresh and processed. The nutritional value of tomato fruits is related to the content of carotenoids, polyphenols, sugars, organic acids, minerals and vitamins. Currently, there is a growing interest in the qualitative and quantitative increase in the content of health-promoting compounds in tomato fruits. VIR Lycopersicon (Tourn.) Mill. genetic resources collection includes 7678 accessions of one cultivated and nine wild species, which in turn provides ample opportunities for searching for information on the variability of the content of biologically active substances and searching for sources with a high content of them in the gene pool. Our work presents the results of the study of 70 accessions of cultivated and wild tomato on the main biochemical characteristics: the content of dry matter, ascorbic acid, sugars, carotenoids, chlorophylls and anthocyanins. As the basis for the selection of accessions for the study, accessions with various colors of fruits, including new accessions with varying content of anthocyanin, were taken. As a result of this study, the amplitude of variability in the content of dry matter (3.72β8.88 and 9.62β11.33 %), sugars (1.50β5.65 and 2.20β2.70 %), ascorbic acid (12.40β35.56 and 23.62β 28.14 mg/100 g), titratable acidity (0.14β0.46 and 0.33β0.48 %), chlorophylls (0.14β5.11 and 2.95β4.57 mg/100 g), carotenoids (0.97β99.86 and 1.03β10.06 mg/100 g) and anthocyanins (3.00β588.86 and 84.31β152.71 mg/100 g) in the fruits of cultivated and wild tomatoes, respectively, was determined. We have determined correlations between the content of dry matter and monosaccharides (r = 0.40, p β€ 0.05), total sugars (r = 0.37, p β€ 0.05) and ascorbic acid (r = 0.32, p β€ 0.05); the content of ascorbic acid and carotenoids (r = 0.25, p β€ 0.05). A high dependence of the content of chlorophyll a and b among themselves (r = 0.89, p β€ 0.05), as well as between the content of chlorophyll b and anthocyanins (r = 0.47, p β€ 0.05), the content of Ξ²-carotene (r = 0.26, p β€ 0.05) and the content of monosaccharides (r = β0.29, p β€ 0.05) has been noted. We have identif ied tomato accessions with a high content of individual chemical substances, as well as with a complex of traits that can be used as sources in breeding for a high content of dry matter, sugars, ascorbic acid, pigments and anthocyanins
Non-financial motivation practices: Megafon and Nestle
The article examines factors which influence the effectiveness of employee motivation, as well as presents the main aspects that need to be taken into account to develop the optimal system of financial and non-financial motivation of employees in international companies. At the same time, a comparative analysis of existing employee motivation practices is provided, using the example of two giant companies: Megafon and Nestle
ΠΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΡΡ ΠΏΠΎΡΡΠ΅Π±Π½ΠΎΡΡΠ΅ΠΉ ΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΠ΅Π»Π΅ΠΉ ΡΠ΅Π½ΡΡΠ°Π»ΡΠ½ΠΎΠΉ Π½Π°ΡΡΠ½ΠΎΠΉ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊΠΈ ΠΊΡΡΠΏΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΠΌΡΡΠ»Π΅Π½Π½ΠΎΠ³ΠΎ Π³ΠΎΡΠΎΠ΄Π° Π΄Π»Ρ ΠΎΠΏΡΠΈΠΌΠΈΠ·Π°ΡΠΈΠΈ Π΅Ρ Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΠ½ΠΎ-ΡΠ΅ΡΡΡΡΠ½ΠΎΠΉ Π±Π°Π·Ρ
Scientific libraries as an essential part of science, education, sociocultural and industrial complex of a region (big academic or industrial city) are engaged in developing information and communication environment. Therefore, systematic developing of library and information space is vital. Within the framework of the project βRegional scientific libraries in the changing science and education environmentβ (Fundamental Studies Program of the Russian Academy of Sciences, 2022β2026), the State Public Scientific and Technical Library of the Russian Academy of Sciences Siberian Branch has been designing the model to adapt regional libraries to modern communications and new methods of scientific publications dissemination within the context of social transformations and changing paradigm of library acquisition of scientific literature and information resources, the services provided to specialists in science and education and meeting their information needs, modified user preferences, behavior and reading styles, and the concept of libraries interaction in building and using their document resources. The authors focus on the science and education space and library and information infrastructure of Novosibirsk (big science and education center) and Western Siberia (Tomsk, Kemerovo Regions and Altay Kray) and, for comparison purposes, that of Chelyabinsk, the large industrial center in the Urals.The authors characterize in brief Chelyabinsk industrial, science and academic specialization and its library system (based on the monitoring findings), as well as the primary results of the study of library users information needs (survey based); they also examine the compliance of document resources of Chelyabinsk Regional Universal Scientific Library to the user information needs to update the conceptual model of library and information services offered to students and specialists.ΠΠ°ΡΡΠ½ΡΠ΅ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊΠΈ, ΡΠ²Π»ΡΡΡΡ Π½Π΅ΠΎΡΡΠ΅ΠΌΠ»Π΅ΠΌΠΎΠΉ ΡΠ°ΡΡΡΡ Π½Π°ΡΡΠ½ΠΎΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ, ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎ-ΠΊΡΠ»ΡΡΡΡΠ½ΠΎΠ³ΠΎ ΠΈ ΠΏΡΠΎΠΌΡΡΠ»Π΅Π½Π½ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ° ΡΠ΅Π³ΠΈΠΎΠ½Π° (ΠΊΡΡΠΏΠ½ΠΎΠ³ΠΎ Π½Π°ΡΡΠ½ΠΎΠ³ΠΎ ΠΈΠ»ΠΈ ΠΏΡΠΎΠΌΡΡΠ»Π΅Π½Π½ΠΎΠ³ΠΎ ΡΠ΅Π½ΡΡΠ°), ΡΡΠ°ΡΡΠ²ΡΡΡ Π² ΡΠΎΠ·Π΄Π°Π½ΠΈΠΈ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎ-ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠΎΠ½Π½ΠΎΠΉ ΡΡΠ΅Π΄Ρ. ΠΡΠΎΠ±Π»Π΅ΠΌΠ° ΡΠΈΡΡΠ΅ΠΌΠ½ΠΎΠ³ΠΎ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΡΠ½ΠΎ-ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π° ΠΊΠΎΠ½ΠΊΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΡΠ΅Π³ΠΈΠΎΠ½Π° ΠΏΠΎΠΏΡΠ΅ΠΆΠ½Π΅ΠΌΡ Π°ΠΊΡΡΠ°Π»ΡΠ½Π°.Π Ρ
ΠΎΠ΄Π΅ Π²ΡΠΏΠΎΠ»Π½Π΅Π½ΠΈΡ Π½Π°ΡΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΠ΅ΠΊΡΠ° Β«ΠΠ°ΡΡΠ½Π°Ρ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊΠ° ΡΠ΅Π³ΠΈΠΎΠ½Π° Π² ΡΡΠ»ΠΎΠ²ΠΈΡΡ
ΠΌΠ΅Π½ΡΡΡΠ΅ΠΉΡΡ Π½Π°ΡΡΠ½ΠΎ-ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΡΠ΅Π΄ΡΒ» (ΠΏΡΠΎΠ³ΡΠ°ΠΌΠΌΠ° ΡΡΠ½Π΄Π°ΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΡΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ Π ΠΎΡΡΠΈΠΉΡΠΊΠΎΠΉ Π°ΠΊΠ°Π΄Π΅ΠΌΠΈΠΈ Π½Π°ΡΠΊ, 2022β2026 Π³Π³.) ΠΠΎΡΡΠ΄Π°ΡΡΡΠ²Π΅Π½Π½Π°Ρ ΠΏΡΠ±Π»ΠΈΡΠ½Π°Ρ Π½Π°ΡΡΠ½ΠΎ-ΡΠ΅Ρ
Π½ΠΈΡΠ΅ΡΠΊΠ°Ρ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊΠ° Π‘ΠΈΠ±ΠΈΡΡΠΊΠΎΠ³ΠΎ ΠΎΡΠ΄Π΅Π»Π΅Π½ΠΈΡ Π ΠΎΡΡΠΈΠΉΡΠΊΠΎΠΉ Π°ΠΊΠ°Π΄Π΅ΠΌΠΈΠΈ Π½Π°ΡΠΊ (ΠΠΠΠ’Π Π‘Π Π ΠΠ) ΠΏΡΠΈΡΡΡΠΏΠΈΠ»Π° ΠΊ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠ΅ ΠΌΠΎΠ΄Π΅Π»ΠΈ Π°Π΄Π°ΠΏΡΠ°ΡΠΈΠΈ Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ Π½Π°ΡΡΠ½ΡΡ
Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊ ΡΠ΅Π³ΠΈΠΎΠ½Π° ΠΊ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΠ΅ ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠΉ ΠΈ Π½ΠΎΠ²ΡΠΌ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½ΠΈΡ Π½Π°ΡΡΠ½ΡΡ
ΠΏΡΠ±Π»ΠΈΠΊΠ°ΡΠΈΠΉ Π² ΠΊΠΎΠ½ΡΠ΅ΠΊΡΡΠ΅ ΡΡΠ°Π½ΡΡΠΎΡΠΌΠ°ΡΠΈΠΉ ΡΠΎΡΠΈΡΠΌΠ°, ΠΏΡΠ΅Π΄ΠΏΠΎΠ»Π°Π³Π°ΡΡΠ΅ΠΉ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠ΅: ΠΏΠ°ΡΠ°Π΄ΠΈΠ³ΠΌΡ Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊ ΠΏΠΎ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠΎΠ½Π΄ΠΎΠ² Π½Π°ΡΡΠ½ΠΎΠΉ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΡ ΠΈ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΡΠ΅ΡΡΡΡΠΎΠ²; ΡΠΈΡΡΠ΅ΠΌΡ ΠΎΠ±ΡΠ»ΡΠΆΠΈΠ²Π°Π½ΠΈΡ ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΡΡΠΎΠ² Π½Π°ΡΡΠ½ΠΎΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ° Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΡΠ½ΠΎ-ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΡΠΌΠΈ ΡΠ΅ΡΡΡΡΠ°ΠΌΠΈ Ρ ΡΡΡΡΠΎΠΌ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΠΏΠΎΡΡΠ΅Π±Π½ΠΎΡΡΠ΅ΠΉ, ΠΌΠΎΠ΄ΠΈΡΠΈΠΊΠ°ΡΠΈΠΉ ΡΠΈΡΠ°ΡΠ΅Π»ΡΡΠΊΠΈΡ
ΠΏΡΠ΅Π΄ΠΏΠΎΡΡΠ΅Π½ΠΈΠΉ ΠΈ ΠΏΡΠ°ΠΊΡΠΈΠΊ ΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΠ΅Π»Π΅ΠΉ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊ; ΠΊΠΎΠ½ΡΠ΅ΠΏΡΠΈΠΈ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ Π½Π°ΡΡΠ½ΡΡ
Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊ ΡΠ΅Π³ΠΈΠΎΠ½Π° ΠΏΡΠΈ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΠΈ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠΈ ΠΈΡ
Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΠ½ΠΎ-ΡΠ΅ΡΡΡΡΠ½ΠΎΠΉ Π±Π°Π·Ρ. ΠΠ±ΡΠ΅ΠΊΡΡ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ β Π½Π°ΡΡΠ½ΠΎ-ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΠ΅ ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²ΠΎ ΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΡΠ½ΠΎ-ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½Π°Ρ ΠΈΠ½ΡΡΠ°ΡΡΡΡΠΊΡΡΡΠ° ΠΠΎΠ²ΠΎΡΠΈΠ±ΠΈΡΡΠΊΠ° (ΠΊΡΡΠΏΠ½Π΅ΠΉΡΠ΅Π³ΠΎ Π½Π°ΡΡΠ½ΠΎΠ³ΠΎ ΠΈ ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ΅Π½ΡΡΠ°), ΡΡΠ±ΡΠ΅ΠΊΡΠΎΠ² ΠΠ°ΠΏΠ°Π΄Π½ΠΎΠΉ Π‘ΠΈΠ±ΠΈΡΠΈ (Π’ΠΎΠΌΡΠΊΠΎΠΉ, ΠΠ΅ΠΌΠ΅ΡΠΎΠ²ΡΠΊΠΎΠΉ ΠΎΠ±Π»Π°ΡΡΠ΅ΠΉ ΠΈ ΠΠ»ΡΠ°ΠΉΡΠΊΠΎΠ³ΠΎ ΠΊΡΠ°Ρ) ΠΈ Π΄Π»Ρ ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ β ΠΊΡΡΠΏΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΠΌΡΡΠ»Π΅Π½Π½ΠΎΠ³ΠΎ ΡΠ΅Π½ΡΡΠ° Π£ΡΠ°Π»Π° β Π§Π΅Π»ΡΠ±ΠΈΠ½ΡΠΊΠ°.Π ΡΡΠ°ΡΡΠ΅ Π΄Π°Π½Π° ΠΊΡΠ°ΡΠΊΠ°Ρ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠ° ΠΏΡΠΎΠΌΡΡΠ»Π΅Π½Π½ΠΎΠΉ, Π½Π°ΡΡΠ½ΠΎΠΉ, ΠΎΠ±ΡΠ°Π·ΠΎΠ²Π°ΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ Π§Π΅Π»ΡΠ±ΠΈΠ½ΡΠΊΠ°, ΡΠΈΡΡΠ΅ΠΌΡ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊ (Π½Π° ΠΎΡΠ½ΠΎΠ²Π΅ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ² ΠΌΠΎΠ½ΠΈΡΠΎΡΠΈΠ½Π³Π°); ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Ρ ΠΏΡΠ΅Π΄Π²Π°ΡΠΈΡΠ΅Π»ΡΠ½ΡΠ΅ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΠΏΠΎΡΡΠ΅Π±Π½ΠΎΡΡΠ΅ΠΉ ΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΠ΅Π»Π΅ΠΉ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊ (ΠΏΠΎ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ°ΠΌ Π°Π½ΠΊΠ΅ΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ), ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΡΡΠΎΠ²Π½Ρ ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΠΈΡ Π΄ΠΎΠΊΡΠΌΠ΅Π½ΡΠ½ΠΎ-ΡΠ΅ΡΡΡΡΠ½ΠΎΠΉ Π±Π°Π·Ρ Π§Π΅Π»ΡΠ±ΠΈΠ½ΡΠΊΠΎΠΉ ΠΎΠ±Π»Π°ΡΡΠ½ΠΎΠΉ ΡΠ½ΠΈΠ²Π΅ΡΡΠ°Π»ΡΠ½ΠΎΠΉ Π½Π°ΡΡΠ½ΠΎΠΉ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΠΊΠΈ ΠΈΡ
ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΡΠΌ ΠΏΠΎΡΡΠ΅Π±Π½ΠΎΡΡΡΠΌ Π΄Π»Ρ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠ΅ΠΉ ΡΠ°Π±ΠΎΡΡ ΠΏΠΎ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠ΅ ΠΊΠΎΠ½ΡΠ΅ΠΏΡΡΠ°Π»ΡΠ½ΠΎΠΉ ΠΌΠΎΠ΄Π΅Π»ΠΈ Π±ΠΈΠ±Π»ΠΈΠΎΡΠ΅ΡΠ½ΠΎ-ΠΈΠ½ΡΠΎΡΠΌΠ°ΡΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ»ΡΠΆΠΈΠ²Π°Π½ΠΈΡ ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΡΡΠΎΠ² ΠΈ ΡΡΠ°ΡΠ΅ΠΉΡΡ ΠΌΠΎΠ»ΠΎΠ΄Π΅ΠΆΠΈ
Endometrial expression of FOX proteins (FOXA1 and FOXA2) in women of reproductive age with different endometrial thickness: prospective cohort comparative study
Aim. To evaluate the expression of FOX proteins (FOXA1 and FOXA2) in the endometrium during the implantation window in women with a history of reproductive dysfunctions with different thickness of the endometrium.
Materials and methods. The prospective cohort comparative study was conducted. The main group included patients with "thin" endometrium (7 mm according to ultrasound on preovulatory days; n=52), the comparison group consisted of women with normal endometrial thickness (7 mm according to ultrasound; n=62; women of both groups with reproductive dysfunctions of unknown reason), the control group included 16 healthy fertile women. Aspiration biopsy of the endometrium was performed on the 68 days after ovulation, as well as venipuncture to obtain a sample of peripheral blood to determine the levels of sex steroids (estradiol E2 and progesterone P). A combined histological and immunohistochemical study of endometrial biopsies was performed.
Results. All women had ovulatory values of progesterone P16.1 nmol/l (68 days after ovulation) and normoestrogenemia (E2, pmol/l) in the blood. E2/P was similar in all groups (p0, 05). A pronounced expression of FOXA1 was noted in women with thin endometrium significantly more often (p0.05) with various hormone-receptor characteristics of the endometrium (42% n=22 out of 52) compared with healthy participants (0%; n=0). Reduced FOXA2 expression in the uterine mucosa was significantly more often detected on 68 days after ovulation in women with "thin" endometrium (56% n=29 of 52) than in women with normal endometrial thickness, both in women from the comparison group and in healthy women from the control group (p0.05). In a generalized analysis of the expression of FOX proteins in the endometrium on days 68 after ovulation, it was generally found that every second (50%; n=57 out of 114) women with a history of reproductive disorders (with a reduced and normal M-echo value) expression of proteomic markers differed from healthy women. In the case of "thin" endometrium, more than two thirds of patients (71%; n=37 out of 52) showed differences in endometrial expression of FOX proteins compared with women without a burdened reproductive history.
Conclusion. In the majority of women (71%) with a thin endometrium and a history of reproductive dysfunctions, the expression of FOX proteins in the endometrium differed from the control group. Overall, endometrial expression of FOX proteins, which is likely to be different from healthy women, in patients with reproductive dysfunctions of unknown origin is a significant predictor of reproductive failure. At the same time, such an isolated indicator as M-echo value 7 mm according to ultrasound data is not an absolute prognostic marker of endometrial receptivity disorders
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