Check Exception Automation (CEA) System

Check Exception Automation (CEA) System is a web application which provides the facility to create and resolve the check exception that occurs after the check is successfully deposited to the American Bank. Checks can be deposited via different channels such as ATM, Cash Vault (which is a kind of check dropping box) and via mobile. There are a number of exceptions that may occur after depositing the check such as missing signature, wrong amount, altered check, duplicate check and missing amount. The older check exception resolution process was manual process. The goal of this project is to automate the check resolution process with no or very little human involvement. This project is implemented using all the advanced technologies such as Java 1.7, Spring 3.1, Spring Security, Apache CXF web services and JQuery. This documentation describes the project plan which explains the requirements with timelines and the methodology used for project life cycle. It also briefly explains about the meeting plans and team building activities during the project development. Furthermore, it explains the problems existed in older system and the benefits expected from the new system. Moreover, this document also covers the basic technical as well as architectural aspects of the project. The project is implemented on agile methodology which is different than traditional waterfall model. This document also explains the interaction strategy and interaction flow among the development teams and business partners

Clinical significance of ovarian stromal blood flow in assessment of ovarian response in stimulated cycle for in vitro fertilization

Background: Several ultrasound parameters have been examined to predict the ovarian response to gonadotropins. The only parameter that has been conclusively proven to predict ovarian response is the antral follicle count. It has been suggested that ovarian blood flow may play a crucial role in the development of ovarian follicles. The present study was planned to prospectively analyse the effect of ovarian stromal blood flow on ovarian responsiveness in terms of number of oocytes retrieved in stimulated cycle for IVF.Methods: Fifty subjects between 22 to 37 years of age with male factor, tubal factor or unexplained infertility underwent controlled ovarian stimulation by the standard “Long protocol”. Ovarian stromal blood flow was recorded on baseline transvaginal sonography on day 2 or 3 of cycle and was correlated with number of oocytes retrieved in IVF cycle.Results: The ovarian stromal blood flow was found to be negatively correlated with age. The number of follicles formed in a subject after stimulation with gonadotropins was negatively correlated with ovarian stromal resistance index and pulsatility index.Conclusions: Ovarian blood flow predicts ovarian responsiveness and hence provides a non-invasive and cost effective prognostic factor of IVF outcome

Hypergonadotropic hypogonadism: looking beyond ovarian senescence

Gonadotropin resistant ovary syndrome (GROS) is a rare cause of primary infertility where ovarian reserve is present but they fail to respond to gonadotropin stimulation. This condition can be easily confused with premature ovarian insufficiency (POI) if thorough workup is not done as in both the cases serum FSH is high, but ovarian reserve is normal in GROS and low or absent in POI. So, we are presenting this case of GROS. A 28-year-old lady presented with oligomenorrhoea since menarche and primary infertility. On workup her serum FSH and LH levels were markedly elevated, serum estradiol was normal. Markers of ovarian reserve, ante Mullerian hormones (AMH) and antral follicle count (AFC), were normal. Her autoantibody assay was also normal. She did not respond to stimulation with high doses of gonadotropins (uHMG). Hypergonadotropic hypogonadism is not always POI. We should not miss diagnosis of GROS where it is possible to have own biological child by in vitro maturation of immature oocytes, whereas in POI donor oocyte is the only fertility option

Genome-wide identification, organization and phylogenetic analysis of Dicer-like, Argonaute and RNA-dependent RNA Polymerase gene families and their expression analysis during reproductive development and stress in rice

<p>Abstract</p> <p>Background</p> <p>Important developmental processes in both plants and animals are partly regulated by genes whose expression is modulated at the post-transcriptional level by processes such as RNA interference (RNAi). Dicers, Argonautes and RNA-dependent RNA polymerases (RDR) form the core components that facilitate gene silencing and have been implicated in the initiation and maintenance of the trigger RNA molecules, central to process of RNAi. Investigations in eukaryotes have revealed that these proteins are encoded by variable number of genes with plants showing relatively higher number in each gene family. To date, no systematic expression profiling of these genes in any of the organisms has been reported.</p> <p>Results</p> <p>In this study, we provide a complete analysis of rice Dicer-like, Argonaute and RDR gene families including gene structure, genomic localization and phylogenetic relatedness among gene family members. We also present microarray-based expression profiling of these genes during 14 stages of reproductive and 5 stages of vegetative development and in response to cold, salt and dehydration stress. We have identified 8 Dicer-like (<it>OsDCLs</it>), 19 Argonaute (<it>OsAGOs</it>) and 5 RNA-dependent RNA polymerase (<it>OsRDRs</it>) genes in rice. Based on phylogeny, each of these genes families have been categorized into four subgroups. Although most of the genes express both in vegetative and reproductive organs, 2 <it>OsDCLs</it>, 14 <it>OsAGOs </it>and 3 <it>OsRDRs </it>were found to express specifically/preferentially during stages of reproductive development. Of these, 2 <it>OsAGOs </it>exhibited preferential up-regulation in seeds. One of the Argonautes (<it>OsAGO2</it>) also showed specific up-regulation in response to cold, salt and dehydration stress.</p> <p>Conclusion</p> <p>This investigation has identified 23 rice genes belonging to DCL, Argonaute and RDR gene families that could potentially be involved in reproductive development-specific gene regulatory mechanisms. These data provide an insight into probable domains of activity of these genes and a basis for further, more detailed investigations aimed at understanding the contribution of individual components of RNA silencing machinery during reproductive phase of plant development.</p

Magnetically retrievable Ce-doped Fe3O4 nanoparticles as scaffolds for the removal of azo dyes

Considering the significant impact of magnetically retrievable nanostructures, herein, Fe3O4 and Ce-doped Fe3O4 nanoparticles were employed as scaffolds for the removal of the Reactive Black 5 (RB5) azo dye. We synthesized the Ce-doped Fe3O4 nanoparticles via hydrothermal treatment at 120 °C for 10 h with varying cerium concentrations (1.5–3.5%) and characterized them using basic techniques such as FTIR and UV-visible spectroscopy, and XRD analysis. The retention of their magnetic behaviors even after cerium amalgamation was demonstrated and confirmed by the VSM results. FESEM and EDX were used for the morphological and purity analysis of the synthesized nanoabsorbents. XPS was carried out to determine the electronic configuration of the synthesized samples. The porosity of the magnetic nanoparticles was investigated by BET analysis, and subsequently, the most porous sample was further used in the adsorption studies for the cleanup of RB5 from wastewater. The dye adsorption studies were probed via UV-visible spectroscopy, which indicated the removal efficiency of 87%. The prepared Ce-doped Fe3O4 nanoabsorbent showed the high adsorption capacity of 84.58 mg g−1 towards RB5 in 40 min. This is attributed to the electrostatic interactions between the nanoabsorbent and the dye molecules and high porosity of the prepared sample. The adsorption mechanism was also analyzed. The kinetic data well-fitted the pseudo-first-order model, and the adsorption capability at different equilibrium concentrations of the dye solution indicated monolayer formation and chemisorption phenomena. Furthermore, the magnetic absorbent could be rapidly separated from the wastewater using an external magnetic field after adsorption

Prospective assessment of mental and physical health of maternal near-miss women: A low-middle-income country's experience

Background: Traumatic birth experience is an unaddressed arena, especially in Asian women, with several societal stigmas lingering around. Aim: A study was undertaken to simultaneously assess the post-partum mental and physical health follow-up of maternal near-miss (MNM) women and compare it with women of uneventful deliveries. Materials and Methods: The prospective cohort study enrolled 88 MNM women (case cohort) and 80 women with an uneventful peri-partum period (control cohort) at the same time. The participants were followed up with Edinburgh Postnatal Depression Scale (EDPS), PTSD Checklist – Civilian Version (PLC-C), and a 36-item short-form-survey form over 6 months after the delivery. Results: The case group had higher mean EPDS and PLC-C scores, with poor quality of life (QOL) performance, compared to the control group at 6 weeks and 3 months, and 6 months follow-up (P < 0.05). At the sixth-week follow-up visit, the study observed that 28 (31.8%) women from the case group required a psychiatry consultation compared to the control group with only two (2.5%) participants (P < 0.001). At 3 months, an evident difference was noted on various QOL parameters, such as limitations due to physical health and emotional problems, energy fatigue, general health, and health change parameters between the two groups (P < 0.05). The difference persisted at 6-month follow-up as well for limitations due to physical health, energy fatigue, and general health parameters only (P < 0.05). Conclusion: There is an urgent need for a multi-departmental collaborative approach at the hospital level and policy-making decisions at higher levels for the mental health of Asian women facing MNM events

F-Box Proteins in Rice. Genome-Wide Analysis, Classification, Temporal and Spatial Gene Expression during Panicle and Seed Development, and Regulation by Light and Abiotic Stress

F-box proteins constitute a large family in eukaryotes and are characterized by a conserved F-box motif (approximately 40 amino acids). As components of the Skp1p-cullin-F-box complex, F-box proteins are critical for the controlled degradation of cellular proteins. We have identified 687 potential F-box proteins in rice (Oryza sativa), the model monocotyledonous plant, by a reiterative database search. Computational analysis revealed the presence of several other functional domains, including leucine-rich repeats, kelch repeats, F-box associated domain, domain of unknown function, and tubby domain in F-box proteins. Based upon their domain composition, they have been classified into 10 subfamilies. Several putative novel conserved motifs have been identified in F-box proteins, which do not contain any other known functional domain. An analysis of a complete set of F-box proteins in rice is presented, including classification, chromosomal location, conserved motifs, and phylogenetic relationship. It appears that the expansion of F-box family in rice, in large part, might have occurred due to localized gene duplications. Furthermore, comprehensive digital expression analysis of F-box protein-encoding genes has been complemented with microarray analysis. The results reveal specific and/or overlapping expression of rice F-box protein-encoding genes during floral transition as well as panicle and seed development. At least 43 F-box protein-encoding genes have been found to be differentially expressed in rice seedlings subjected to different abiotic stress conditions. The expression of several F-box protein-encoding genes is also influenced by light. The structure and function of F-box proteins in plants is discussed in light of these results and the published information. These data will be useful for prioritization of F-box proteins for functional validation in rice