Development and assessment of a digital X-ray software tool to determine vertebral rotation in adolescent idiopathic scoliosis

BACKGROUND CONTEXT: The amount of vertebral rotation in the axial plane is of key importance in the prognosis and treatment of adolescent idiopathic scoliosis (AIS). Current methods to determine vertebral rotation are either designed for use in analogue plain radiographs and not useful in digital images, or lack measurement precision and are therefore less suitable for the follow-up of rotation in AIS patients.PURPOSE: This study aimed to develop a digital X-ray software tool with high measurement precision to determine vertebral rotation in AIS, and to assess its (concurrent) validity and reliability.STUDY DESIGN/SETTING: In this study a combination of basic science and reliability methodology applied in both laboratory and clinical settings was used.METHODS: Software was developed using the algorithm of the Perdriolle torsion meter for analogue AP plain radiographs of the spine. Software was then assessed for (1) concurrent validity and (2) intra-and interobserver reliability. Plain radiographs of both human cadaver vertebrae and outpatient AIS patients were used. Concurrent validity was measured by two independent observers, both experienced in the assessment of plain radiographs. Reliability-measurements were performed by three independent spine surgeons.RESULTS: Pearson correlation of the software compared with the analogue Perdriolle torsion meter for mid-thoracic vertebrae was 0.98, for low-thoracic vertebrae 0.97 and for lumbar vertebrae 0.97. Measurement exactness of the software was within 5 degrees in 62% of cases and within 10 degrees in 97% of cases. Intraclass correlation coefficient (ICC) for inter-observer reliability was 0.92 (0.91-0.95), ICC for intra-observer reliability was 0.96 (0.94-0.97).CONCLUSIONS: We developed a digital X-ray software tool to determine vertebral rotation in AIS with a substantial concurrent validity and reliability, which may be useful for the follow-up of vertebral rotation in AIS patients. (C) 2015 Elsevier Inc. All rights reserved.</p

The innervation of the cervical facet joints - an anatomical and histological approach

INTRODUCTION: Cervical facet joint pain syndrome accounts for a great amount of cervical pain worldwide. This study aims to provide updated knowledge of cervical facet joint innervation with new anatomical findings. MATERIALS AND METHODS: Twenty-seven cervical facet joints and their innervating structures were dissected from five halves of three human neck specimens. Histologic staining was used to confirm that the samples were nervous tissues, and all samples were documented with photography. RESULTS: Histology: Thirty-six assumed facet joint branch samples were obtained and stained. Twenty-two of these were confirmed to be nervous tissue. Therefore, 61% of the samples were identified as facet joint branches. Of all samples, 28% were not nerves. Dissection: At least one medial branch was clearly identified at each dissected cervical level. At some cervical levels, more than one medial branch was found. Anatomical differences, such as a plexus-like innervation in the high cervical region, were observed. Direct facet joint branches were also discovered. These branches originate directly from the dorsal root of the spinal nerve and were independent from medial branches during their direct pathway toward the facet joint. CONCLUSION: Direct cervical facet joint branches were identified and a more diverse innervation pattern than previously described of the cervical facet joints was found. This article is protected by copyright. All rights reserved

10. Thoracic pain.

Approximately 5% of the patients referred to outpatient pain clinics suffer thoracic pain. Thoracic pain in this article is limited to thoracic radicular pain and pain originating from the thoracic facet joints. Thoracic radicular pain is characterized by radiating pain in the localized area of a nervus intercostalis. The diagnosis of thoracic facet pain should be considered if the patient complains of paravertebral pain that is aggravated by prolonged standing, hyperextension, or rotation of the thoracic spinal column. Based on the analyses of the results in the literature combined with experience in pain management, symptoms, assessment, differential diagnosis, and treatment possibilities of thoracic radicular pain and thoracic facet pain are described and discussed. Conservative treatment consists of medications according to the World Health Organization pain ladder. Transcutaneous electrical nerve stimulation is an option. Physical therapy is usually applied in the form of manual therapy. Interventional treatment may be considered when conservative treatment fails. For thoracic radicular pain, the available evidence on efficacy and safety supports recommendation (2 C+) of pulsed radiofrequency treatment of the ganglion spinale (DRG). If this treatment has a short-lasting effect and the pain is segmental, then radiofrequency treatment of the ganglion spinale (DRG) can be performed. Recommendation (2 C+) is applicable. However, extensive skills are required to perform this procedure above the level of Th7. This treatment should take place in specialized centers. For thoracic facet pain, radiofrequency treatment of the ramus medialis of the thoracic rami dorsales is recommended (2 C+).</p

Anatomy of abdominal anterior cutaneous intercostal nerves with respect to the pathophysiology of anterior cutaneous nerve entrapment syndrome (ACNES): A case study

Introduction: Anterior Cutaneous Nerve Entrapment Syndrome is allegedly caused by entrapment of an intercostal nerve in a fibrous ring in the rectus abdominis muscle leading to neuropathic pain. Surgical release of the strained nerve (neurectomy) obtains adequate pain relief in 70% of patients. Standard anatomy texts and previous research however might underestimate the complex network of nerve branches in the abdominal wall, leading to suboptimal treatment results and misguided pathophysiology. Material and methods: One fresh frozen cadaver with no gross previous pathology was dissected to map the course of intercostal nerves from the lateral abdominal wall to their nerve terminals in the subcutis of the anterior abdominal wall. Histology was performed to differentiate between nerve tissue and fascia. Special attention was payed to fibrous ring like structures. Results: Five major neurovascular bundles were identified (T8-T12). Fibrous rings were not found intramuscularly but in the posterior rectus sheath, if present. Multiple neural interconnections at the lateral border of the posterior rectus sheath were found. Per dermatome several small branches perforated the rectus abdominis muscle. Conclusions: The trajectory of nerves in the abdominal wall appears to be more complex than previously suggested, which should be addressed when for instance a neurectomy is performed. : The trajectory of nerves in the abdominal wall is more complex than previously suggested, which should be addressed when a neurectomy is performed in patients with Anterior Cutaneous Nerve Entrapment Syndrome (ACNES). Keywords: Intercostal nerve, Abdominal wall, Pain, ACNES, Entrapment, Neurectom

Mechanoreceptors observed in a ligamentous structure between the posterior horn of the lateral meniscus and the anterior cruciate ligament

Purpose A histological study of a structure between fgvbthe posterior horn of the lateral meniscus and the anterior cruciate ligament. Methods Bilateral fresh-frozen cadaveric knees of two male donors (age 71 and 76 years) with no history of prior knee injury were examined. All dissections were performed by one experienced orthopaedic surgeon. Haematoxylin and Eosin staining was used to reveal tissue morphology. Goldner trichrome staining was used to evaluate the connective tissue. S100 and PGP 9.5 labelling were used for immunohistochemical analysis. Results In all cadaveric knees, a structure between the posterior horn of the lateral meniscus and the anterior cruciate ligament was identified. Histological analysis confirmed the ligamentous nature of this structure. Furthermore, Golgi tendon organs were observed within the ligamentous structure. Conclusion This is the first study showing the presence of mechanoreceptors within the ligamentous structure between the posterior horn of the lateral meniscus and the anterior cruciate ligament. The ligamentous structure could contribute to stability of the knee by providing proprioceptive input, while preservation of the ligamentous structure might ensure a better functional outcome after surgery

Carpal Tunnel Syndrome

Carpal tunnel syndrome (CTS) is a common disorder. In the majority of cases, patients with CTS can be diagnosed by means of appropriate history taking. Nerve conduction examination of the nervus medianus is the most important additional diagnostic test and is the best predictor of symptom severity and functional status in idiopathic CTS. Treatment option depends on the severity of the symptoms and the degree of functional daily limitations. If few limitations are present, splinting or corticosteroid injections are preferred. Surgical interventions are reserved for the more severe conditions resulting in significant disability. Interventional pain treatment such as pulsed radiofrequency could be an addition to the future treatment options for CTS

The Sc-GAP makeover flap:eliminating the need for position changes in gluteal flap breast reconstruction

Background The gluteal region is one of the many alternative donor sites for autologous breast reconstruction. However, the harvest of the gluteal flap is rather difficult, and the major drawback of gluteal flaps has been the need for position changes for flap harvest and inset. A new approach of a gluteal flap is introduced, based on the septocutaneous perforators of the superior gluteal artery: the septocutaneous gluteal artery perforator (Sc-GAP) makeover flap. Methods A prospective study was performed in Maastricht University Medical Center between January 2018 and December 2019. Patients who underwent a Sc-GAP makeover flap breast reconstruction in the Maastricht University Medical Center and have had preoperative magnetic resonance angiography (MRA) of the abdomen between January 2018 and June 2019 were included. Results Nine patients underwent breast reconstruction with thirteen Sc-GAP makeover flaps, of which nine flaps were innervated. Indications were the abdomen not being available as a donor site (n = 4) or the flank region was preferred as a donor site by the patient (n = 5). The total operative time was 430 min on average (range 311-683). Mean flap weight was 638 g (range 370-1004) and the mean ischemia time was 53 +/- 9.96 min. Coupler size used was 2.0-2.5 mm. All flaps survived. Conclusion The Sc-GAP makeover flap overcomes the disadvantages of the conventional gluteal flaps, especially by eliminating the need for position changes during the reconstruction procedure. It is a reliable flap that provides sufficient volume and good esthetic outcomes. Level of evidence: Level IV, therapeutic study