189 research outputs found
Improvement in Opto-Electrical Properties of GaN MSM Photodetector by Contact Work-Function Selection
Overall , this work evaluates the role of different metal contacts in improving electrical properties of GaN MSM (metal-semiconductor-metal) photodetector. The metal contacts were investigated in this work are AI , In, Pt. ITO and ZnO. Prior to the metalization , GaN layer was deposited on m-plane sapphire (AI203) substrate using electron beam (e-beam) evaporator, followed by ammonia annealing treatment to improve 111 -V stoichiometric balance. Subsequently , a metal mask consisting of two terminals, each with 3 inter-digitized fingers was aligned over -9 mm2 of the GaN samples. Contacts on each MSM photodetector were deposited by either RF/DC sputtering. Next each GaN MSM photodetector were annealed at 400 °C for 10 minutes in ambient air to diffuse the metal contact layer into th e GaN layer. The bes t spectral response of th e GaN MSM was observed at -360 nm GaN MSM photodetector with Pt contact shows a Schottky IV curve due to the large contact work -function . On the other hand. ohmic IV curve was observed on the remain ing GaN MSM photodetector IV measurement under dark and illuminated conditions shows a gain of -34 times between bias voltage or 1.5 V to 5.0 V. Responsivity measurement under pulsing UV light illumination was conducted to investigate the rise and fall time for each GaN MSM photodetector
Factors associated with low birthweight in term pregnancies: A matched case-control study from rural Pakistan
Low birthweight (LBW) remains a significant public health problem in Pakistan and further understanding of factors associated with LBW is required. We conducted a hospital-based matched case control study to identify risk factors associated with LBW in a rural district of Pakistan. We found that illiteracy (AOR: 2.68; 95% CI: 1.59 - 4.38), nulliparity (AOR: 1.82; 95% CI: 1.26-2.44), having a previous miscarriage/abortion (AOR: 1.22; 95% CI: 1.06-2.35), having \u3c 2 antenatal care (ANC) visits during last pregnancy (AOR: 2.43; 95% CI: 1.34-2.88), seeking ANC in third trimester (AOR: 3.62; 95% CI : 2.14-5.03), non-use of iron folic acid during last pregnancy (AOR: 2.72; 95% CI: 1.75-3.17), having hypertension during last pregnancy (AOR: 1.42; 95% CI: 1.13-2.20), being anemic (AOR: 2.67; 95% CI: 1.65-5.24) and having postpartum weight o
Exchangeable zinc pool size at birth in Pakistani small for gestational age and appropriate for gestational age infants do not differ but are lower than in US infants
Objectives: Small for gestational age (SGA) infants are more susceptible to infectious morbidity and growth faltering compared to their appropriate for gestational age (AGA) counterparts. Zinc supplementation of SGA infants may be beneficial but the underlying susceptibility to zinc deficiency of SGA infants has not been examined.Methods: In a community-based, observational, longitudinal study in a peri-urban settlement of Karachi, Pakistan, we compared the size of the exchangeable zinc pools (EZPs) in term SGA and AGA infants at birth and at 6 months of age, hypothesizing that the EZP would be lower in the SGA group. To measure EZP size, a zinc stable isotope was intravenously administered within 48 hours of birth (n = 17 and 22) at 6 months (n = 11 and 14) in SGA and AGA infants, respectively. Isotopic enrichment in urine was used to determine EZP.Results: No significant difference was detected in the mean (±standard deviation) EZP between SGA and AGA infants at birth, with values of 9.8 ± 3.5 and 10.1 ± 4.1 mg/kg, respectively (P = 0.86), or at 6 months. Longitudinal EZP measurements demonstrated a significant decline in EZP relative to body weight in both groups at 6 months (P \u3c 0.001). Mean EZP (adjusted for body weight) size at birth for the combined Pakistani groups was significantly lower than AGA infants at birth in the United States (P = 0.017).Conclusions: These results did not support a difference in zinc endowment between SGA and AGA Pakistani infants. They, however, do suggest lower in utero zinc transfer to the fetus in a setting where poor maternal nutritional status may confer a high susceptibility to postnatal zinc deficiency
Histopathological and cholinesterase changes in the gills of Clarias gariepinus as a result of cadmium exposure
Aim : The cholinesterase (ChE) based inhibition and histopathological studies from fish were investigated and represented in this study to develop as one of the great potential biomarkers for heavy metals monitoring. Methodology : In this study, the histopathological study of gills were observed a under microscope. The capability of ChE extracted from the gills of Clarias gariepinus was assessed for declining Cd. ChE was purified through affinity chromatography and continued with the optimisation and inhibition study (IC50) of cholinesterase. Results : Histopathological study of gills was carried out and several changes such as aneurysm, necrosis and lamella fusion were noted. Purification fold obtained from purified enzyme was 1.15 with 30% a yield specific activity 20.726. The optimum temperature for purified AChE was 35°C along with acetylthiocholine iodide (ATC) as a preferable substrate that had the highest Vmax value of 0.5452 U mg'1 and the lowest Km value of 0.0311 mM. The optimum pH was observed to be 10 of Tris-HCl as a medium. Meanwhile, the IC50 of cadmium was 6.808 mg ľ with R2 value of 0.9532. Interpretation : The result of the study can be used as a tool for further developing a biomarker for the detection of heavy metals in aquatic ecosystems. In addition, the baseline data provided can also be used for designing a kit, which would give rapid and accurate result
3D MODELING FOR ROCK ART DOCUMENTATION USING LIGHTWEIGHT MULTISPECTRAL CAMERA
This paper discusses the use of the lightweight multispectral camera to acquire three-dimensional data for rock art documentation application. The camera consists of five discrete bands, used for taking the motifs of the rock art paintings on a big structure of a cave based on the close-range photogrammetry technique. The captured images then processed using commercial structure-from-motion photogrammetry software, which automatically extracts the tie point. The extracted tie points were then used as input to generate a dense point cloud based on the multi-view stereo (MVS) and produced the multispectral 3D model, and orthophotos in a different wavelength. For comparison, the paintings and the wall surface also observed by using terrestrial laser scanner which capable of recording thousands of points in a short period of time with high accuracy. The cloud-to-cloud comparison between multispectral and TLS 3D point cloud show a sub-cm discrepancy, considering the used of the natural features as control target during 3D construction. Nevertheless, the processing also provides photorealistic orthophoto, indicates the advantages of the multispectral camera in generating dense 3D point cloud as TLS, photorealistic 3D model as RGB optic camera, and also with the multiwavelength output
THE SUITABILITY OF TERRESTRIAL LASER SCANNING FOR STRATA BUILDING
During the recent years, the used of terrestrial laser scanning (TLS) is becoming rapidly popular because of its ability in several applications, especially the ability to observe complex documentation of complex building and observe millions of point cloud in three-dimensional in a short period. Users of strata plan usually find it difficult to translate the traditional two-dimensional (2D) data on maps they see on a flat piece of paper to three-dimensional (3D). The TLS is able to record thousands of point clouds which contains very rich of geometry details and made the processing usually takes longer time. In addition, the demand of strata survey work has made the surveyors need to obtain the data with full of accuracy and time saves. Therefore, the aim of this study is to study the limitation uses of TLS and its suitability for strata building survey. In this study, the efficiency of TLS Leica C10 for strata building survey was determined in term of its accuracy and comparing with Zeb-Revo Handheld Mobile Laser Scanning (MLS) and the distometer. The accuracy for scanned data from both, TLS and MLS were compared with the Distometer by using root mean square error (RMSE) formula. Then, the 3D model of the building for both data, TLS and MLS were produced to analyze the visualization for different type of scanners. The software used; Autodesk Recap, Autodesk Revit, Leica Cyclone Software, Autocad Software and Geo Slam Software. The RMSE for TLS technique is 0.001m meanwhile, RMSE for MLS technique is 0.007 m. The difference between these two techniques is 0.006 m. The 3D model of building for both models did not have too much different but the scanned data from TLS is much easier to process and generate the 3D model compared to scanned data from MLS. It is because the scanned data from TLS comes with an image, while none from MLS scanned data. There are limitations of TLS for strata building survey such as water and glass window but this study proved that acquiring data by TLS is better than using MLS
THREE-DIMENSIONAL RECORDING AND PHOTOREALISTIC MODEL RECONSTRUCTION FOR VIRTUAL MUSEUM APPLICATION – AN EXPERIENCE IN MALAYSIA
In recent years, museums are utilizing the ability of virtual reality (VR) technologies to visualize their collections in three-dimensional (3D) environment. The demands for 3D digitization of cultural heritage have increase greatly to facilitate the development of virtual museum. Among the available techniques, the use of laser scanning for digital recording and 3D reproduction of the heritage sites and archaeological artefacts are technically more reliable due to its rapid and high resolution data capture. However, the suitable 3D laser scanners used greatly depend on the level of details and size of an object. This research used medium and close-range type of laser scanners to digitally record the heritage objects. The aim of this research was to develop methodology framework for digital recording and 3D reproduction of archaeological artefact and heritage sites in Malaysia by using terrestrial laser scanning technology. Besides, this research focused on the reconstruction of photorealistic 3D models based on the colour information yield by close-range photogrammetry. The colour descriptions were obtained either by built-in camera or externally integrated camera on the laser scanner. For better colour descriptions, external images were captured by independent Nikon D300s digital camera. The geometric model accuracy of A’Famosa and terracotta Buddha statuette was in 5 mm and 0.41 mm respectively. 3D flythrough animation was rendered by using the coloured point clouds model. The development of 3D Virtual Walkthrough Museum (3DVWM) utilized the 3D PDF document and SCENE WebShare platform to offer realistic visualization experience to the visitors where the reality-based models could be manipulate in 3D geometric aspects and use of metric analysis. Thus, 3DVWM can facilitate the virtual museum application in Malaysia and enable wider visitors to virtually appreciate the cultural heritage in Malaysia. Thus, this indirectly stimulates the tourism industry in our country
Gaze–mouse coordinated movements and dependency with coordination demands in tracing.
Eye movements have been shown to lead hand movements in tracing tasks where subjects have to move their fingers along a predefined trace. The question remained, whether the leading relationship was similar when tracing with a pointing device, such as a mouse; more importantly, whether tasks that required more or less gaze–mouse coordination would introduce variation in this pattern of behaviour, in terms of both spatial and temporal leading of gaze position to mouse movement. A three-level gaze–mouse coordination demand paradigm was developed to address these questions. A substantial dataset of 1350 trials was collected and analysed. The linear correlation of gaze–mouse movements, the statistical distribution of the lead time, as well as the lead distance between gaze and mouse cursor positions were all considered, and we proposed a new method to quantify lead time in gaze–mouse coordination. The results supported and extended previous empirical findings that gaze often led mouse movements. We found that the gaze–mouse coordination demands of the task were positively correlated to the gaze lead, both spatially and temporally. However, the mouse movements were synchronised with or led gaze in the simple straight line condition, which demanded the least gaze–mouse coordination
Maternal vaccination against COVID-19 and neonatal outcomes during Omicron: INTERCOVID-2022 study
Background: In early 2023, when Omicron was the variant of concern, we showed that vaccinating pregnant women decreased the risk for severe COVID-19-related complications and maternal morbidity and mortality. Objective: This study aimed to analyze the impact of COVID-19 during pregnancy on newborns and the effects of maternal COVID-19 vaccination on neonatal outcomes when Omicron was the variant of concern. Study design: INTERCOVID-2022 was a large, prospective, observational study, conducted in 40 hospitals across 18 countries, from November 27, 2021 (the day after the World Health Organization declared Omicron the variant of concern) to June 30, 2022, to assess the effect of COVID-19 in pregnancy on maternal and neonatal outcomes and to assess vaccine effectiveness. Women diagnosed with laboratory-confirmed COVID-19 during pregnancy were compared with 2 nondiagnosed, unmatched women recruited concomitantly and consecutively during pregnancy or at delivery. Mother-newborn dyads were followed until hospital discharge. The primary outcomes were a neonatal positive test for COVID-19, severe neonatal morbidity index, severe perinatal morbidity and mortality index, preterm birth, neonatal death, referral to neonatal intensive care unit, and diseases during the neonatal period. Vaccine effectiveness was estimated with adjustment for maternal risk profile. Results: We enrolled 4707 neonates born to 1577 (33.5%) mothers diagnosed with COVID-19 and 3130 (66.5%) nondiagnosed mothers. Among the diagnosed mothers, 642 (40.7%) were not vaccinated, 147 (9.3%) were partially vaccinated, 551 (34.9%) were completely vaccinated, and 237 (15.0%) also had a booster vaccine. Neonates of booster-vaccinated mothers had less than half (relative risk, 0.46; 95% confidence interval, 0.23-0.91) the risk of being diagnosed with COVID-19 when compared with those of unvaccinated mothers; they also had the lowest rates of preterm birth, medically indicated preterm birth, respiratory distress syndrome, and number of days in the neonatal intensive care unit. Newborns of unvaccinated mothers had double the risk for neonatal death (relative risk, 2.06; 95% confidence interval, 1.06-4.00) when compared with those of nondiagnosed mothers. Vaccination was not associated with any congenital malformations. Although all vaccines provided protection against neonatal test positivity, newborns of booster-vaccinated mothers had the highest vaccine effectiveness (64%; 95% confidence interval, 10%-86%). Vaccine effectiveness was not as high for messenger RNA vaccines only. Vaccine effectiveness against moderate or severe neonatal outcomes was much lower, namely 13% in the booster-vaccinated group (all vaccines) and 25% and 28% in the completely and booster-vaccinated groups, respectively (messenger RNA vaccines only). Vaccines were fairly effective in protecting neonates when given to pregnant women ≤100 days (14 weeks) before birth; thereafter, the risk increased and was much higher after 200 days (29 weeks). Finally, none of the neonatal practices studied, including skin-to-skin contact and direct breastfeeding, increased the risk for infecting newborns. Conclusion: When Omicron was the variant of concern, newborns of unvaccinated mothers had an increased risk for neonatal death. Neonates of vaccinated mothers had a decreased risk for preterm birth and adverse neonatal outcomes. Because the protective effect of COVID-19 vaccination decreases with time, to ensure that newborns are maximally protected against COVID-19, mothers should receive a vaccine or booster dose no more than 14 weeks before the expected date of delivery
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