7th Drug hypersensitivity meeting: part two

No abstract availabl

An adult-onset egg allergy

World Allergy and Asthma Congress of the European-Academy-of-Allergy-and-Clinical-Immunology and World-Allergy-Organization -- JUN 22-26, 2013 -- Milan, ITALYWOS: 000325142905180European Acad Allergy & Clin Immunol, World Allergy Or

Characteristics of sensitization to cockroaches in patients with respiratory allergy in Izmir, Turkey

Cockroach (CR) infestation is an important cause of sensitization in allergic individuals. We investigated the prevalence and the characteristics of sensitivity to CRs in patients with respiratory allergy in Izmir. Three hundred and fifty-four patients with allergic rhinitis and/or asthma responded to a questionnaire and were prick tested with CR extract as well as with extracts of other household allergens. One hundred and twenty-eight of these patients (36.2%) were sensitized to CRs; sensitivity was 1.4 times more frequent among men compared to women. The prevalence of asthma was 39.1% in the group of individuals sensitized to CRs and 28.8% in the non-sensitized group (95% confidence intervals (CI) 1.005-2.508; P = 0.047). Moderate, persistent asthma was reported more often in patients sensitized compared to patients not sensitized to CRs (30% versus 18%). In patients with allergic rhinitis, the mean time before they became asthmatic was less in the group sensitized compared to those not sensitized to CRs (2.8 ± 3.4 versus 4.5 ± 5.2 years, P = 0.045). More than half the patients sensitized to CRs were also sensitized to cats (68.9%), to dog dander (62.1%) and to Dermatophagoides pteronyssinus (59.8%). We conclude that allergy to CRs is present in a large number of atopic individuals in Izmir. The existence of allergy to CRs seems to shorten the delay in the onset of asthma in patients with allergic rhinitis. © 2004 Elsevier SAS. All rights reserved

Chlamydia pneumoniae arthritis in a patient with common variable immunodeficiency

WOS: 000228578300013PubMed ID: 15875533Background: Arthritis is an important and sometimes life-threatening complication in patients with common variable immunodeficiency (CVID). Objective: To describe a patient with CVID and arthritis due to Chlamydia pneumoniae, which is usually regarded as a respiratory tract pathogen and has not previously been detected in the synovial fluid by cell culture technique. Methods: Routine bacteriologic, virologic, mycologic, and tuberculosis cultures were performed. The patient's synovial fluid was examined for fastidious organisms that might be causative pathogens of arthritis, such as chlamydiae, and special cell culture methods were used. Serologic tests were performed to determine viral and bacteriologic etiology. Results: The patient had a history of recurrent respiratory tract infections, and the latest exacerbation was followed by arthritis. Cytologic examination of the fluid yielded abundant lymphocytes. Chlamydia pneumoniae was detected in synovial fluid specimens by cell culture technique. Her nasopharyngeal swab and sputum culture specimens were also positive for this pathogen. She was diagnosed as having arthritis caused by C pneumoniae and was given antibiotherapy. Conclusion: Chlamydia pneumoniae should be kept in mind as a causative pathogen in patients with CVID and arthritis, especially when effusion fluid is full of lymphocytes rather than polymorphonuclear cells and no organism is grown on routine cultures